Has anyone had Stem cell Therapy? I listened to a seminar locally recently and it sounds interesting...

[greatjohn]

I found it interesting...but also see it called "nonsense" and "quackery" on some online sites. The testimonials are "too good to believe"...but isn't that what we want...something that's too good to believe? LOL. I was thinking it would help with the muscle, tendon and joint pain that I have from Lupron. Does anyone have experience with it?

John

[ctarleton]

Don't know about the quacks. A San Diego company gave a science-based presentation on their involvement as of Feb 2018. Earlier work involving multiple myeloma. Trying it out for prostate cancer. Currently still working on it with mice. Involves "CAR-T" technology. Might be quite a while before human Phase I, II, III Clinical Trials, I'd guess. See:

poseida.com/2018/02/14/pose...

Charles

[greatjohn in reply to ctarleton]

I'm thinking more of the companies opened now...who inject you with stem cells from placentas...but that was very interesting.

[Tall_Allen in reply to greatjohn]

Trophoblasts? That could be dangerous - there is a kind of cancer called choriocarcinoma that results when trophoblasts go wild. I wrote a novel about that -- Thaw's Hammer

[j-o-h-n in reply to Tall_Allen]

Just a Plug!

Thaw's Hammer Paperback – August 13, 2016

(on Amazon).

by Allen Edel (Author)

Good Luck and Good Health.

j-o-h-n Friday 03/30/2018 12:08 PM EDT

[greatjohn in reply to j-o-h-n]

I Google the book. It does sound interesting, but other than the author having prostate cancer... I don't see a connection.☮

[Hidden in reply to ctarleton]

CAR-T is not related to stem cells. T cells are well differentiated cells ("leaf" cells), not stem cells.

[greatjohn]

oh...I just read the above comment. Hmmm.

[Hidden]

quackery.

It is impossible to promise, or suggest, wonderful results. There have been no trials.

While there is significant interest in the role of stem cells (as opposed to "leaf" cells), it is not at all clear how to taget them (cancer stem cells). Just injecting you with healthy stem cells is severly disconnected from medical practice, normally understood.

There are prostate cells that have gone back up the differentiation chain in order to metastasize. You can read more under the term EMT or endothelial mesenchymal transition. It seems to be a part of CTCs =circulating tumor cells. But the area is murky to the bese of my knowwwledge. People do announce good and bad ranges for CTC's, and CellSearch is one machine that is used as a detector.

[greatjohn]

I was thinking of their use more for the pain that lupron causes in muscles and tissue and tendons and joints.... Not as a cure for cancer.

[Tjc1]

I looked into it for ED kinda veered toward lots of money or very little results. So for cancer definately not ready yet.

[greatjohn]

Thanks! ~~I'm leaning away from it. My pain from lupron in the joints, tendons and muscles is what I was hoping it might offer relief from. It IS expensive...about 3500.00 per injection. Guess I'll just keep on keeping on....with the status quo. ~~John

[JLS1]

Thought you might be interested in this:

Using stem cells to generate an immune attack against cancer

by Arlene Weintraub | Feb 15, 2018 2:41pm

fiercebiotech.com/research/...

[greatjohn in reply to JLS1]

hmm...I think there is hope for "the miracle" on the horizon....sound so promising. Happy Easter/Passover/Weekend

John