Xtandi Monotherapy = To Lupron or Cas... - Advanced Prostate...

Advanced Prostate Cancer

21,016 members26,195 posts

Xtandi Monotherapy = To Lupron or Castration

gusgold profile image
12 Replies

I just read a study where Xtandi Monotherapy was equal to Lupron with way less long term side effects

Below meet my pal Gustave having a hippo for lunch...he has killed 300 men...I plan on wrestling Gustave when Xtandi fails...why go out on a morphine drip when you can go out in style.

Gus

i.pinimg.com/736x/af/29/48/...

Written by
gusgold profile image
gusgold
To view profiles and participate in discussions please or .
Read more about...
12 Replies
Dan59 profile image
Dan59

From what I experienced , and what I have read from men who post, IMO the side effects of xtandi are a little worse than lupron. In particular the fatigue. Also adding xtandi when Lupron fails gives more time yet.

youtube.com/watch?v=941N0bn...

gusgold profile image
gusgold in reply to Dan59

Dan,

they were talking in terms of bone and muscle loss and increased lipids

gusgold profile image
gusgold in reply to gusgold

Dan,

when Xtandi fails will Lupron still work

Dan59 profile image
Dan59 in reply to gusgold

That is a good question , I do not know anyone who started xtandi after Lupron.

in reply to Dan59

I don't think it's approved yet for monotherapy, only for MCRPC. My understanding is that trials are underway.

ncbi.nlm.nih.gov/pubmed/276...

IBstan profile image
IBstan in reply to Dan59

I am going to go on Xtandi for 6 mos., shortly following advice of my oncologist. I have a had brachytherapy , radiation and a course of Lupron before these treatments and following these therapies... PSA recently at 11.0 .

rococo profile image
rococo in reply to gusgold

According to dr dr barken lupron worked after casodex monotherapy, might just as well after xtandi. Rocco

BigRich profile image
BigRich in reply to Dan59

I really liked that video.

Thank you Dan.

Rich

Nicnatno profile image
Nicnatno in reply to BigRich

Wait until mama alligator finds out.

tarhoosier profile image
tarhoosier

I am currently on Xtandi, 1-2 40 mg/day and hormone sensitive. No LHRH drug for the last two years. Both my oncologists say that if Xtandi loses effectiveness then LHRH drug will restore low psa. In other words, the reverse of the normal prescribing protocol.

gusgold profile image
gusgold in reply to tarhoosier

that is really good news if Xtandi resistance does not mean castrate resistant

j-o-h-n profile image
j-o-h-n

Do you think the gator or the leopard was on Xtandi Monotherapy?

Good Luck and Good Health.

j-o-h-n Friday 03/16/2018 5:52 PM EDT

You may also like...

Enzalutamide/Xtandi monotherapy as ADT with fewer side effects than Lupron

breast will also help when done before starting with Enzalutamide monotherapy. Another side effect...

Xtandi monotherapy is very effective

that the monotherapy avoids bone loss. Therefore, Xgeva is probably not required. The monotherapy...

Xtandi for castrate resistant PC

I just started Xtandi a couple of weeks ago after becoming castrate resistant. I was on Firagon,...

Memory loss with Lupron and Xtandi

at NIH for checkups and 3-month Lupron until November of 2017, when PSA rose to 2.5 (original was 16

NUBEQA (darolutimide) as MONOTHERAPY (no lupron or similar)?

or will soon be as a monotherapy without first line ADT like casodex or Lupron. One gent says...