ODM-201: I can't find much information... - Advanced Prostate...

Advanced Prostate Cancer

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ODM-201

Blair77 profile image
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I can't find much information about its efficacy. Does anyone have information?

Thx

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Blair77
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Here's some information about the two trials currently underway.

ncbi.nlm.nih.gov/pubmed/284...

This drug shows promise to be an improvement over Enzalutamide (Xtandi) so I think a lot of people are watching it. I posted about this a few weeks ago.

Here's something from the article (link above) "One advantage is that darolutamide has been found to block the activity of all tested/well-known mutant ARs in prostate cancer, including the recently identified clinically-relevant F876L mutation that produces resistance to Enzalutamide and Apalutamide."

I don't think there's much information available about it. It's disappointing to me that the Darolutamide (ODM-201) trial for metastatic cancer is only taking patients wth no previous treatment. That leaves out so many people who could potentially benefit from it.

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