Melatonin and prostate cancer

[Coldwell01]

Has anyone got any information about melatonin being useful as a preventative or as a useful medication in fighting prostate cancer.

[kainasar]

Try to access the Mem Sloan Kettering Cancer Ctr web page for alternative medicine - herbs or use AboutHerbs app.

[Magnus1964]

A good night sleep is always good for cancer. I have been taking it for years.

[Coldwell01]

Yes but I read online that melatonin may stop or slow cancer spread and may prevent the cancer altogether.

[maley2711 in reply to Coldwell01]

are there peer-reviewed studies????? lots of stuff "online". Yes, a secret that the conspiring Docs don't want us to know?

[dadzone43 in reply to Coldwell01]

Yeah. THAT's the information. Anecdotes. Nothing proven. Always couched in "this is the cure they don't want you to know about" It works; it sells.

[rosatt1]

I only use Melatonin to help me sleep at night.

[Ausi]

Here’s a compelling graph from a study I’ve kept, I’ll try and find it and post.

Melatonin

[Ausi in reply to Ausi]

healthunlocked.com/api/redi...

I’m not sure if this link works but as Nal said, as above, Patrick has put out a fair bit on this, pjoshea.

[Garbonzeaux in reply to Ausi]

That graph is probably not specifically for APC, since it appears to show a median survival time of ~12.5 years with melatonin use. A miracle drug for sure, if true.

[Pcnmyy]

The following are links for studies on Melatonin and Prostate Cancer:

pubmed.ncbi.nlm.nih.gov/341...

pubmed.ncbi.nlm.nih.gov/339...

[RonnyBaby]

I've been taking 20 mg - time released - nightly (sometimes more) for years and my results have been favourable (not a cure - don't believe the cure part').

You find it to be beneficial IMO.

[pjoshea13]

healthunlocked.com/advanced...

healthunlocked.com/advanced...

healthunlocked.com/advanced...

-Patrick

[Nous]

hi Coldwell01 ... here's some info that you might find useful ...

"Prostate cancer has high metastatic potential. Men with higher urinary levels of the sleep hormone melatonin are much less likely to develop advanced prostate cancer compared with men with lower levels of melatonin. Melatonin has shown anticancer activity in experimental investigations.Nov. 29, 2020"

"Melatonin impedes prostate cancer metastasis by suppressing MMP-13 expression" ... pubmed.ncbi.nlm.nih.gov/332... ... i myself take Melatonin 10mg at bedtime ... prescribed by my naturopath ... best wishes ... Nous

[SpencerBoy11]

Been taking for many years, yet I am here.

[Sauerkraut]

I have been taking 60-80mg of melatonin every night for 21 years as it's a strong anti-oxident and I like sleep. Now I have prostate cancer. For prostate cancer it's just another horse paste blither.

[GeorgeGlass]

I tried to increase from 300 mcg (Life extension) to 3 mg, and my sleep has been worse this week. Everyone has different tolerance, but it seems like amounts like 20-50 mg might be too much of a good thing, like many supplements, where a little is helpful, and a lot is toxic. Patrick is usually right about stuff, but I am amazed that he is taking 50 mg without issue. What is it that makes melatonin helpful at slowing prostate cancer? Is it due to sleep improvement or does it directly affect the cancer itself? I'm also a little concerned that melatonin reduced dopamine, which is a mood booster/stress reducer, so if you have the melatonin stay in your system for several daylight hours as well, it could ultimately have a negative effect on your mental well-being, and thus, possibly the cancer growth.

I found this on a website, and it seems like it reflects my response to melatonin, and my reduced sleep quality as I raise the amount levels, albeit I've only tried the 3 mg for four days. 3mg was the amount used in the Russian study that claimed that it slowed or reduced prostate cancer.

Here's the article quote:

"How much melatonin do you need?

Most people overdo it with melatonin by taking upward of 10 milligrams or more prior to bed and then claim it doesn’t work. Taking too much melatonin can actually cause rebound insomnia —either rendering the supplement ineffective or worse, exacerbating your already sleepless nights further.

You only need tiny doses of melatonin to support your natural sleep cycle. As little as 1-3 mg about an hour before you go to bed can boost your melatonin by 20 times. If it still doesn’t work for you, it’s likely your sleep problems have other causes and need further investigation by a doctor.

What should I do if melatonin doesn’t work?

While melatonin can be helpful in some cases to regulate the sleep cycle, supplementing with a pill does not need to be your first line of defense against sleepless nights. For many of our Parsley Health members with sleep issues, establishing a nightly routine which includes dimming the lights, refraining from using screens an hour before bed, and setting the stage for rest actually helps to prepare their mind and body for the onset of sleep.

If melatonin doesn’t work for you, or worse, melatonin is keeping you awake, our doctors and health coaches help provide insight around tools such as meditation, deep breathing, and journaling that can help to manage stress levels prior to hitting the pillow. Studies show mindfulness-based stress reduction practices such as these help to improve the quality, duration, and onset of sleep even in those with diagnosed sleep issues.

Even if you’ve tried meditation, melatonin, and mindfulness without any improvement to your sleep, our team of doctors regularly help our members to dive deeper to find the root cause of sleep disturbances—analyzing things such as hormones, the gut microbiome, and cortisol levels to address any underlying imbalances that may be making you prone to poor sleep."

[CurrentSEO]

I take 50-60mg a night for approximately a year. Sleep is good and no side effects.