Hello everyone. My husband and I have joined this forum because of my husband's illness. He has advanced prostate cancer with mets all over his body but no pain and the PSA is at 11 at the moment. He was diagnosed in 2003 and was on different hormone therapies for many years until his PSA shot up to 250 three years ago. He was then put on Aberaterone, which brought the PSA down to under 1. But it has started to go up again and we are now faced with the question: What to do next? Just wait and, should he be in pain ever, treat him with Chemotherapy? Come off the Aberaterone for a while and go back on it again to see if that has any effect? Or try Chemotherapy straight away? We would be very grateful if you could share your experience/your opinion with us. Best wishes, Mel and Paul.