I'm new in these parts :). Originally diagnosed with PC 4 years ago. Cancer had spread so surgery was not an option. I went for radiation and, after 8 weeks of radiation and two years of androgen deprivation therapy (adt), I was in pretty good shape with a PSA of .01. A year ago my PSA shot up to 20 and I went back on adt which lowered my PSA to 2. Recently my PSA went to 9 and after a bone scan I was confirmed with metastatic CRPC. Though radiation kicked the crap out of me side effects from adt have been minimal. I'm about to go on Xgeva, Zytiga and Prednisone along with the Lupron I'm already on. Interested in what side effects any of you on these meds might be experiencing.