I have a close friend who has lost about 20 pounds in the past year and I was worried about him and suggested he get to his urologist. So he recently went to his urologist for his colonoscopy and a PSA test. The PSA hadn't changed. It was 1.1, last year was 1.12, the previous year, 1.1 but the colonoscopy showed a polyp. The Dr said because of its location, he wanted to do a biopsy of the prostate where he found three positive samples. He said no treatment, lets just watch and wait. I am concerned because of the weight loss, even though the PSA would never had given him an indication that anything was wrong. Any thoughts? I am trying to get him to go for a second opinion here.