When we returned to the UK, my husband was treated at Addenbrookes for his WG. Up till this time, he had just been on steriods but Addenbrookes put him on Methotrexate and started decreasing his Pred. He's now on 25mg a week of Meth, and was down to 10mg of Pred per day. He keeps having problems with rashes and respiratory system, sinuses etc so he's now gone up to 15mg of Pred a day. It seems that the hoped for result of Meth keeping his WG under control is not working.
He's got a specialist appt on Weds although she admits she doesn't know a lot about WG so we're going to ask to be referred back to Addenbrookes again.
My question really is, have other people been put on one of these immune supprescent drugs, found they don't achieve anything and then changed to something else? I'm sure this is the case, but he's worried that by changing, he might get worse first before starting to improve.
Any comments before we see the specialist would be appreciated.