Hi, can someone tell me what normal titre le... - Vasculitis UK
Hi, can someone tell me what normal titre levels are and also what is a protinase 3 antibody level?
ANCA titre of <1/20 is considered negative/normal
There are two protinase 3 tests.
The older PR3 has a negative range of 0-7
The newer PR3s is scored negative for values 0-3
However, please remember positive results aren't always indicative of active disease and vice versa.
Its exact role in the function of the neutrophil is unknown (Wikipedia)
Healthy wishes.
Thanks Martin, I had bloods and a CXR done in mid Feb but its only now I'm getting these back. WG 12 yrs
I have a titre of 1;40 and a strong positive protinase level. Just wondering if I should give my consultant a buzz as I only see him once a year and thats in October
I'm a big believer in taking action asap on every occasion. I have WG too and am one of a number of patients who don't fit the 'standard model' when it comes to test results. The most important indicator for me is simply how I feel and I'm fortunate to have a wonderful local consultant here in Cumbria that respects that. I'm also treated at Addenbrookes where they too are very aware that test results are just a potential part of the picture.
David Jayne recommended I get my bloods tested every couple of months (which I do) and am fortunate to be able to log onto my hospital's Renal View (although I've no kidney involvement) and monitor my own results. I tend to watch for trends e.g. upward moving C-ANCA, CRP and falling IgG levels) and prompt actions before they move out of the normal range (which they rarely do).
I'd certainly contact your consultant if I were in your position unless perhaps the results you have are 'normal' for you?
Hi Martin, I emailed my consultant with the results and he replied with " these results are satisfactory" therefore I am a happy bunny again. Many thanks 
