Hello I live in the US and my dearest friend has just been diagnosed with GPA. She is 56 years old and has never been sick a day in her life. Last year she seemed to be getting colds that would last for a couple days then would go away. Nothing to alarming, however just in the past few months she developed a presistant dry cough and crushing fatigue along with painful joints. She just brushed it off as beeing over stressed and the symptoms would go away but came back more until she went in to a doctor who did every test under the sun. Then suddenly she became very sick and went to the emergency. They kept her for two weeks doing a CT scan and scaring the hell out of her with comments of inopperable lung cancer and saying she had Pnumonia witch she never had. Then the gave her a biopsy of the lung and sent her home with a bunch of antibiotics. The biopsy came back with no cancer and they said they were not able to figure out what was wrong. Mean while she lay there getting sicker and sicker not eating and wasting away for a week until her brother took her to a different hospital where the on call emergency doc looked at her and right away knew what it was. They got her in a room and checked her kidneys witch were at 4 percent she was almost dead. She had to have s blood transfusion and dyalisis. They did a kidney biopsy and blood tests and it came back positive for Wegengers GPA. Now she is on dyalisis three times a week as well as the treatment. My question is it possible to reverse the kidney damage with the drugs and be able to get of the machine or is it pretty much that for life or a transplants? I want so badly to give her some positive feed back thank you for any help or any story's you might have. Still very hopeful.