My mum was diagnosed with Microscopic Polyangiitis in May 2014 and initially was treated with high dose prednisolone and several cycles of cyclophosphamide infusion and then went on to Azathioprine and low dose prednisolone and she has been on the latter for over a year now. Her mobility suffered hugely initially and gradually she was able to mobolise with a zimmer frame and then last September (2015) she progressed to using a rollator and was able to get up from her chair and mobilise independently. However, since November 2015 her mobility has retracted and we have seen her consultant and he said her 4 weekly blood checks were fine. She has now hit an all time low depression with not being able to mobilise more than a few feet without having to sit down and I wonder if anyone at all can suggest anything that may help her? We are desperate to get her back to mobilising out to the car to get her socialising but she cannot manage and in the last couple of weeks she has lost her appetite and is sleeping more during the day and appears disinterested in what's going on round about her. My mum is 84 and prior to being diagnosed in May 2014 she was very fit for her age and had never been near a hospital since she had me 50 years ago. It's killing me to see her like this but nobody seems concerned about her apart from my dad and I. Thank you in advance.