I've been taking 25mg of Levothyroxine to support my remaining thyroid for about 8 mths. The endo guy increased it to 50mg per day in April. I gradually noticed that my skin was changing. The fronts of my forearms are feeling rough and grainy, likewise the skin across the back of my shoulders and front of my chest. If I massage my head it feels like I have sand in my hair. I've tried skin scrubs but these don't make any difference; also tried good moisturisers. My facial skin is also now very dry and prone to outbreaks of spots. My problem in going back to gp with this is that I can't prove it's Levo and can't see a good alternative to Levothyroxine available. I'm also taking iron supplement, calcichew D and B12 injections. I started the B12 injections at same time as increase in thyroid meds. The dilemma is pinning down which med is causing the problem. Have other Levo users experienced skin problems?