Has anyone successfully used reformulated Euthy... - Thyroid UK

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Has anyone successfully used reformulated Euthyrox?

HashimotosSucks profile image

I just received my new order. The seller has replaced my usual brand with Euthyrox without informing me. I have read horror stories about how it stopped working for people after they added mannitol. In France, Merck even had to bring the old formula back. It seems many patients saw their TSH increase and free T4 drop on it. I am not sure it would be a good idea to even try it. Has anyone here taken the new Euthyrox without your health deteriorating?

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HashimotosSucks
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14 Replies
CreakingGate47 profile image
CreakingGate47

You say “the seller”

Am I to assume this is a private source?

HashimotosSucks profile image
HashimotosSucks in reply toCreakingGate47

Yes.

HashimotosSucks profile image
HashimotosSucks in reply toCreakingGate47

How is that relevant to my question?

CreakingGate47 profile image
CreakingGate47 in reply toHashimotosSucks

It may not be relevant. The seller I use stopped stocking it for some reason and says it’s not now available.

That’s all.

CreakingGate47 profile image
CreakingGate47 in reply toHashimotosSucks

Old post - but may be of interest.

healthunlocked.com/thyroidu...

HashimotosSucks profile image
HashimotosSucks in reply toCreakingGate47

Interesting! Yes, I think I should avoid even trying Euthyrox. I cannot find one single report of it working for anyone.

CreakingGate47 profile image
CreakingGate47 in reply toHashimotosSucks

It doesn’t sound as though it’s a recent reformulation though.

HashimotosSucks profile image
HashimotosSucks in reply toCreakingGate47

No, it’s from 2020 or 2021. I have used other brands (Unipharma, Levotiron) but all legit sellers have disappeared. I then found Berlthyrox, a German brand, which also worked well, but now it is also unavailable. It seems only Euthyrox/Eutirox is available without a prescription now.

HashimotosSucks profile image
HashimotosSucks in reply toHashimotosSucks

I complained, and am told by seller that Berlthyrox (by Berlin Chemie) has recently been reformulated to contain mannitol so identical to Euthyrox.  helvella , I know you have a list somewhere, have you heard of this?

helvella profile image
helvella in reply toHashimotosSucks

Sounds very questionable to me. The 2020 product information (which was the same in 2013 - so no changes in all those years) says (in German):

Die sonstigen Bestandteile sind:

CalciumhydrogenphosphatDihydrat, Mikrokristalline

Cellulose, Carboxymethylstärke Natrium (Typ A)

(Ph. Eur.), Dextrin (aus Maisstärke), langkettige Partial

glyceride

By automatic translation that is:

The other ingredients are:

Calcium hydrogen phosphate dihydrate, microcrystalline cellulose, sodium carboxymethyl starch (type A)

(Ph. Eur.), dextrin (from corn starch), long-chain partial glycerides

So, no lactose, no mannitol. Why on earth would they change to include a questionable excipient?

However, I have no special access. Changes could have occurred since 2020. But German pharmacies are generally quite good at updating the information they make available. And 2020 is the most recent I can find. If there has been a change, I suspect it would have to have been within the past few months for it not to have appeared on German sites.

I'd ask for evidence before believing them. Like a copy of the product documentation which clearly says it contains mannitol. Seems that mannitol is Mannit in German.

HashimotosSucks profile image
HashimotosSucks in reply tohelvella

Thank you, I will look into it! My last order was in December and it was fine.

HashimotosSucks profile image
HashimotosSucks in reply tohelvella

I found an official site where it says Berlthyrox was reformulated in early 2022 and its name was changed to L-Thyrox BC. Below from Google translate (I guess that since I have been taking Berlthyrox, they have been selling the old version which is no longer available):

The excipients calcium hydrogen phosphate dihydrate, dextrin (from corn starch), sodium glycolate, and long-chain partial glycerides have been replaced with cysteine ​​hydrochloride monohydrate, pregelatinized starch, corn starch, magnesium oxide, and talc. The active ingredient, levothyroxine sodium, remains unchanged.

helvella profile image
helvella in reply toHashimotosSucks

And not the same as Merck Euthyrox!

I hadn't found any mention of the rename but that would explain why I didn't find anything more recent.

HashimotosSucks profile image
HashimotosSucks in reply tohelvella

Sorry, it’s L-Thyroxin BC!

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