Antihistamines ?

[Calceolaria]

Over recent years, I seem to have developed hay fever type symptoms and I’d just pop some loratidine or whatever. Now I hear this might not be ideal for hypo people. Quercetin is mentioned as a helping supplement.

Thoughts anyone please?

[Lily905]

Quercetin is good it helped my hay fever. But I find taking a teaspoon of local unpasteurised honey every day works better for me.

[Calceolaria in reply to Lily905]

Thank you. I’d forgotten about that!

[Hedgeree]

Hi Calceolaria,

Some on the forum use Fexofenadine Hydrochloride brand name 'Allevia' You can also get the generic one which is cheaper.

I don't know which brands of antihistamines are suitable for those with hypothyroidism but I take the 'Allevia' ones as they are lactose free and don't upset my tum. Hope that helps? 🙂

[Calceolaria in reply to Hedgeree]

Thank you very much. I also have early kidney issues so have to check everything twice!

[catpotter44]

I couldn't stand antihistaminesas they just made me more stuffy. I find excellent relief from quercetin, as well as teas such as rooibos and nettle.

[Calceolaria in reply to catpotter44]

Thank you. I have rooibos and will resurrect it!

[Calceolaria in reply to catpotter44]

How much quercetin do you take btw? I read it also may have protective qualities re kidneys.

[catpotter44 in reply to Calceolaria]

I take 500 (cant remember if that mcg or mg...but it'll be obvious). I think i have read before that you can taor more, but I'm not 100% sure, so you'd need to check.

As for kidney benefits, I'm not sure.

I hope you can find some relief!

[Calceolaria in reply to catpotter44]

Thank you so much.

[Watamu]

Hi Calceolaria, I have suffered histamine intollerance for years but never knew what it was, found that I couldn't tolerate wine unfortunately, then other foods caused problems. It was there all year round but worse when the pollen count was high. Not just stuffed up nose, dizziness, itchy eyes etc. but a general feeling of flue type symptoms. there was very little information about histamine problems a few years ago but now it seems to be everywhere. Some of the issues mirror my hashimotos symptoms and it can be difficult to separate the two. I tried Loratadine several years ago but it zonked me out, I slept for several hours during the day. I had bought six boxes of the stuff. Luckily I still have them and in desperation I have started using them again, I take half a tab (5mg in the morning and 5 just before bed). I have been doing this for a week now and definitely feel better, have been able to do some gardening late afternoons. I also started taking T3 just over a year ago so whether the addition of T3 helps me to metabolise the Loratadine?? who knows. I grasp at anything which relates to Hashimotos and histamine intollerance. I watched a very good YouTube video a while ago with Dr. John Campbell and Dr. Tina Preece. She has a daughter who suffered badly and no one was able to find out her problem until some medic suggested MCAS (mast cell activation syndrome). This seems to be connected to all sorts of immune conditions. Have a look at it. Loratadine is ok to take with Hashi - I did a google search

These are results for is Loratadine ok to take with hashimoto's

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Yes, loratadine (Claritin) is generally considered safe to take with Hashimoto's disease. It's a common antihistamine used to manage allergy symptoms, and it doesn't have any known major drug interactions with the medications typically used to treat Hashimoto's, such as levothyroxine.

Elaboration:

• Loratadine and Hashimoto's:

Hashimoto's is an autoimmune thyroid disorder that can sometimes lead to increased histamine levels, potentially contributing to allergic reactions. Loratadine is an antihistamine, which works by blocking histamine receptors, thus reducing allergy symptoms.

• • Levothyroxine and Loratadine:

Levothyroxine is a synthetic thyroid hormone used to treat Hashimoto's and other forms of hypothyroidism. There are no known significant drug interactions between levothyroxine and loratadine.

• • Safety and Other Considerations:

Loratadine is generally considered safe for use, but some people may experience drowsiness or other side effects. If you have any concerns about taking loratadine with your Hashimoto's medication, it's always best to consult with your doctor or pharmacist.

• • Other Antihistamines:

Other antihistamines like fexofenadine (Allegra) and cetirizine (Zyrtec) are also commonly used and generally safe to take with thyroid medications.

• • Histamine and Hashimoto's - Dr. Izabella Wentz, Pharm D

The Histamine and Thyroid Connection. Those with thyroid imbalances, including Hashimoto's, may be more susceptible to histamine i...

Thyroid Pharmacist

nhs.uk

Allergies and Thyroid Disorders - Wyndly

26 Feb 2025 — Managing Hashimoto's can help alleviate allergy symptoms and improve overall health. ... Autoimmune thyroid disorders l...

Also more info -

Medications for the Treatment of MCAS

Medications, as we mentioned, provide symptom relief and act as a diagnostic tool in the beginning. Some common MCAS medications include:

• Emergency Medications – Adrenaline-based interventions, such as epinephrine (EpiPens) open the airways and work to address anaphylaxis.

• Mast cell stabilizers – Medications, such as ketoifen and sodium cromoglicate, stabilize mast cells and reduce the release of mediators.

• Mediator blockers – Mediator blockers, such as H1 and H2 antihistamines (diphenhydramine, loratadine, ranitidine, or famotidine), anti-leukotrienes, and anti-prostaglandins, help block the effects of mast cell mediators.

• Corticosteroids – Corticosteroids, such as prednisone, help to reduce inflammation.

• Vitamin & Mineral Supplements – Vitamins, such as vitamins C & D, Magnesium, and probiotics contribute to mast cell stabilization, preventing inflammatory responses, and the production, regulation, and breakdown of histamines.

• Omalizumab – This medication blocks the binding of IgE to receptors and helps reduce mast cell reactivity and sensitivity, helping to reduce the risk of anaphylactic reactions.

Hope this info is helpful and you feel some relief. High pollen time is a pain, just when the weather is warming up we can't enjoy the sun.

[Calceolaria in reply to Watamu]

Thank you so much for all of that interesting and valuable information from your own research. I have speed read it through and will spend some time with it. I’m glad that you may have found a way to relieve your current symptoms.

[Watamu in reply to Calceolaria]

Glad to help. Do find time to look at that YouTube. Tina Preece was on our local TV station during Covid, she is a very knowledgable woman, also specialised in menopause issues. I think she left the NHS because she felt restricted.

[Watamu in reply to Calceolaria]

Also I did try Quercetrin in 2023, then had liver problems which resolved themselves. I'd stopped all supplements in case they had adverse effects. Was also taking huge doses of vit C , this was before I had found out that citrus fruits are high in histamine, so still trying to find vitimin C supplements compatible with histamine intollerance. its a minefield out there. This useful list of Histamine Compatibility foods i got from the video.

Swiss Interest Group Histamine Intolerance - then go to Food Compatibility List Histamine

This is amazing, lists all foods which may cause a problem. But of course everyone is different and lots of these foods I have no problem with. I used to be able to eat oranges then I think I overloaded on them when making fresh orange juice and couldn't tolerate them. May give them another go soon. I love oranges. Apparently we have a limit as to how much histamin we can tolerate, a bit like a bucket of water, when it reaches a certain limit and we go over that we have a problem. I'm just aware of what foods are a problem to me and eat very little of them, or abstain altogether for a while, then give them another go. Its encouraging to know that we don't have to avoid these foods for ever, we can slowly start to reintroduce them and see what our tolerance level is. Good luck.

[Calceolaria]

Gosh, even more amazing info! Thank you.

[mothsballs]

I have been looking into taking quercetin as an antihisamine, but a study by the NIH said it was a thyroid inhibitor along with CoQ10, so I have been put off.Maybe it needs to be viewed with caution.

[Calceolaria in reply to mothsballs]

Thanks for this. I’ll give it a miss then!