I conceived normally in 2019 and had my first child. I developed Hashis after that pregnancy and it was picked up on as I developed secondary infertility. Got pregnant again eventually with TSI treatment. Now I would like to try for a third but the TSI is not working. No money for IVF. I am still struggling with cognitive symptoms on T4 only and have been told not to try combination T4/T3 until I’m done having kids. I can put up with this but since the fertility treatment isn’t working and I feel that my body is not working well on T4 only I can’t help but wonder why on earth wouldn’t I try to actually optimise my thyroid function using combination therapy and would it perhaps help me to conceive? If my brain is not functioning well how do I know my reproductive system is? I get delayed (late) ovulation often. There’s not much else I can try and I’ve been given no reason for the infertility …. I have 2 copies of DIO2 polymorphism.
T3 helped anyone get pregnant? : I conceived... - Thyroid UK
T3 helped anyone get pregnant?
previous post
Dec:
Iron: 11.5 (Ref 9-30)
TSAT: 15% (Ref 10-50)
B12: 359 (Ref 139-651)
Folic Acid: 17.1 (Ref 7-46.4)
Very low vitamin levels need improved to GOOD levels as first steps
Exactly what vitamin supplements are you taking
Aiming for minimum
Ferritin over 70
Serum B12 over 500
Folate at top of range
Vitamin D no result
Aim for at least over 80nmol
Only add one supplement at a time then wait 2 weeks to assess before adding another
Retest thyroid and vitamin levels 2 months after adding last supplement
Meanwhile get
FULL iron panel test for anaemia via Monitor my health or Medichecks
And test TSH, Ft4 and FT3 together
ALWAYS test early morning and last dose Levothyroxine 24 hours before test
do you always get same brand Levothyroxine at each prescription
Are you on gluten free/dairy free diet
Thank you but I didn’t post in relation to those results which are months old. I have since got an iron transfusion, iron and TSAT have come way up, Ferritin is rising slowly, I am supplementing and doing all I can to raise it but it’s hard to get it up, was over 30 on my last check. I take all possible supplements and my vitamin levels are optimal. Thyroid levels are mid range, TSH stays around 1. I am on 100 Eltroxin.
My question was specifically on T3 and fertility.
Supplements currently taking:
Prescribed by fertility doc:
Folic acid
Vitamin D
CoQ10
I also take:
Proceive pre conception multi
B12
Magnesium
Iron + vitamin C
Omega fish oil
Alpha lipoic acid
NAC
Also on:
Aspirin
Steroids
Stims + progesterone etc TSI meds
Steroids frequently lower TSH and/or cortisol
Are you testing cortisol levels
I am only on the steroids for two weeks post ovulation when I’m undergoing treatment so overall it’s not a factor relating to my question. Thanks
Pregnancy
Before even considering TTC levels need to be stable
verywellhealth.com/infertil...
Pregnancy guidelines
NICE guidelines that if hypothyroid or subclinical you should see endocrinologist BEFORE TTC
cks.nice.org.uk/topics/hypo...
See pages 7&8
btf-thyroid.org/Handlers/Do...
Also here - dose increase in levothyroxine as soon as pregnancy test confirms conception
cuh.nhs.uk/patient-informat...
thyroidpharmacist.com/artic...
Low ferritin, low thyroid levels and miscarriage
preventmiscarriage.com/iron...
Low iron and hypothyroid
endocrineweb.com/news/thyro...
Folate and B12 and Neural tube defects and autism
healthunlocked.com/thyroidu...
I do appreciate your reply but I’ve come across all of the above before and this does not relate to my question. I am doing everything I can, gluten free, almost dairy free, no egg whites, low processed food, take my Eltroxin correctly and check my levels correctly, take many many vitamins, antioxidants etc. I don’t know what else more I can do hence why I am now asking about T3.
It’s very difficult, but not impossible to find an endocrinologist prepared to allow T3 during pregnancy
posts that mention T3 and pregnancy
healthunlocked.com/search/p...
What’s your Ft4 and Ft3 results on current dose Levo
Thyroid levels are mid range,
You will very likely need Ft4 higher than mid range if on only Levo …typically Ft4 70-80% through range
If you can go private I know of an endocrinologist based in Bristol (but all consults are done online) who I know prescribes and supports the use of T3 in pregnancy.
I see her and she's fab.
I’m in Ireland. Do they only take UK patients? Could you send me on name?
Will do.
Please add on your profile that you are in Ireland
And age and gender helpful too
Will do and I’ve posted bloods below.
I know nothing about getting and staying pregnant with or without thyroid issues. But if you have the Dio2 polymorphism x 2, you are a poor converter of T4 to T3. So you very likely do need T3. Can you share your last FT4 and FT3 results?
I have the polymorphism from one parent. Trouble is, my GP hadn't got a clue what I was showing him when I took my test results to show him. I had to go to see a private endo to get T3 and I have to pay for it. You probably won't conceive with low FT3 and if you did, the chances of miscarriage are high. Can you ask to see a specialist in pregnancy at the hospital? They should have more idea than your GP.
Thanks, I’ve posted bloods below. I’m learning here but I thought my bloods seemed fine. From my own learning about DIO2 (mainly from Dr Antonio Bianco) the issue won’t show up in bloods but the localised tissue hypothyroidism can still be there, particularly in the brain. I keep getting told my bloods are perfect but then why do I still have symptoms and infertility?!
BLOOD RESULTS:
Results from Jan 25:
TSH : 1 (0.27 - 4.2)
FT4 : 19 (12 - 22)
FT3 : 4.9 (3.1 - 6.8)
Results from Nov 24:
TSH : 1.7 (0.27 - 4.2)
FT4 : 16.3 (12 - 22)
FT3 : 4.6 (3.1 - 6.8)
These were done morning bloods 24hrs since last dose of Eltroxin.
I think you need to increase your fT3 level. This may mean lowering your fT4 a little too as your TSH looks good. As you have the DIO2 polymorphism I don’t think you are converting adequately. Perhaps a little T3 would help.x
Your November results showed:
FT4 43% through range
FT3 40.54% through range
Your January results showed:
FT4 70% through range
FT3 48.65% through range
November showed a decent level of T4 to T3 conversion. January slipped.
The results aren't as bad as I though they might be, but still if optimal for you needs FT3 in the 50-60% range, you need a dose increase of some kind, and T3 is probably the best route given the conversion issues you likely have.
Has anyone felt better on just T4 rather than T4/T3?
Eltroxin and Natural Dessicated Thyroid Queries
Does anyone worry that they’ll never get their medication “optimal”? 
Thyroid UK T3 Survey
Why would you - or why did you change from a T4 & T3 combination to T3 only?
