Thyroid question : Hello all, I am new to here. I... - Thyroid UK

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Thyroid question

Brandyglass profile image
19 Replies

Hello all, I am new to here. I have had my thyroid medication changed to Teva. And now experiencing palpitations, panic attacks plus my fingers. Arms and legs even my buttocks ache and I get a tingling sensation and nerve jumping. Could it be the medication? I've read on here some people are experiencing issues when changing from a different brand.

I was previously on Accord and Wockhart and had no issues for years.

I feel so unwell I am not able to go to work.

Any help would be much appreciated if anyone has had these issues witn Teva and how it was rectified

Thank you

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Brandyglass profile image
Brandyglass
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19 Replies
Buddy195 profile image
Buddy195Administrator

I experienced similar symptoms and filled in a yellow card to report adverse side effects. I then requested GP stated the brands I can tolerate on my prescription, so it doesn’t happen again. So far, my pharmacy has been able to fulfil this 🤞

healthunlocked.com/redirect...

Brandyglass profile image
Brandyglass in reply toBuddy195

Thank you for your feedback. Can I ask if you stopped taking the medication prior to getting an appointment with your doctor? Was it Teva you were on and if so did you have the same symptoms as me ?

Buddy195 profile image
Buddy195Administrator in reply toBrandyglass

Yes it was Teva for me. I did stop taking it, but I had some of my previous prescription left to tide me over for a few days. I had increased anxiety, fast pulse, tremor, palpitations and gastric issues.

Speak with GP practice to re issue a new prescription as soon as you are able.

Buddy195 profile image
Buddy195Administrator

I’ve just realised you are a new member- welcome to the forum !

How long have you been diagnosed with a thyroid condition? Do you have any blood test results to share (please include ranges as these can vary between laboratories)?

Brandyglass profile image
Brandyglass in reply toBuddy195

All bloods came back fine. Sorry I don't have the range.

SlowDragon profile image
SlowDragonAmbassador in reply toBrandyglass

Please add actual results

You are legally entitled to printed copies of your blood test results and ranges.

ALWAYS test thyroid levels early morning and last dose levothyroxine 24 hours before test

The best way to get access to current and historic blood test results is to register for online access to your medical record and blood test results

UK GP practices are supposed to offer everyone online access for blood test results. Easiest option is NHS app, you may need "enhanced access" to see blood results.

If you can’t currently see test results online, simply ask receptionist at GP surgery to give you access. You will need to have photo ID with you.

This currently only applies in England, not across the whole of the UK. Nether Scotland nor N.Ireland have released an NHS app for patients. (Scotland supposedly due in December '24.) Wales has an app, but only for booking appointments, repeat prescriptions and amending personal details

Link re access

patients-association.org.uk...

healthunlocked.com/thyroidu...

In reality some GP surgeries still do not have blood test results online yet

Alternatively ring receptionist and request printed copies of results. Allow couple of days and then go and pick up.

Buddy195 profile image
Buddy195Administrator in reply toBrandyglass

Please be aware that when medics say fine/ normal/within range, this may not be the same as OPTIMAL where you feel most well. That’s why we encourage members to share test results and ranges with us.

Brandyglass profile image
Brandyglass

Thank you so much for this makes me feel I am not alone in this. I will revert to my old medication until I see the doctor.

SlowDragon profile image
SlowDragonAmbassador

Teva upsets many, many people

(Though for a few it’s the best option)

Contact Practice manager /gp pharmacist and request a replacement prescription ASAP

Explain your severe reaction to change in brand of levothyroxine

That you have put in a yellow card report

yellowcard.mhra.gov.uk

That you need urgent replacement levothyroxine

Request a note is added to all future prescriptions “No Teva”

Many people find Levothyroxine brands are not interchangeable.

Most easily available (and often most easily tolerated) are Mercury Pharma or Accord

Mercury Pharma make 25mcg, 50mcg and 100mcg tablets 

Mercury Pharma also boxed as Eltroxin. Both often listed by company name on pharmacy database - Advanz

Accord only make 50mcg and 100mcg tablets. Accord is also boxed as Almus via Boots, 

Wockhardt is very well tolerated, but only available in 25mcg tablets. Some people remain on Wockhardt, taking their daily dose as a number of tablets 

July 2024

Crescent levothyroxine. Dosages: 12.5, 25, 50, 75, 100

(Not yet known if all approved dosages are or will be available).

Excipients: lactose monohydrate, maize starch, croscarmellose sodium, gelatin and magnesium stearate.

Lactose free brands - currently Vencamil or Teva

Vencamil is lactose free and mannitol free. originally only available as 100mcg only, but 25mcg, 50mcg and 75mcg tablets became available Sept 2024

Prior to March 2023 Vencamil was called Aristo

Vencamil often very well tolerated/best option for many people

How to get Vencamil stocked at your local pharmacy

healthunlocked.com/thyroidu...

Posts discussing Vencamil

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu....

Teva makes 12.5mcg 25mcg, 50mcg, 75mcg and 100mcg

Many patients do NOT get on well with Teva brand of Levothyroxine.

Teva is lactose free, but contains mannitol as a filler instead of lactose, which seems to be possible cause of problems. Mannitol seems to upset many people, it changes gut biome 

Helpful post about Teva

healthunlocked.com/thyroidu...

Posts that mention Teva

healthunlocked.com/search/p...

Teva poll

healthunlocked.com/thyroidu...

Relatively new ……Hillcross brand

This is a box, rather than a brand. 50mcg and 100mcg are Accord brand….but beware 25mcg is Teva brand

Helpful post about different brands

healthunlocked.com/thyroidu...

List of different brands available in U.K.

thyroiduk.org/if-you-are-hy...

Once you find a brand that suits you, best to make sure to only get that one at each prescription.

Watch out for brand change when dose is increased or at repeat prescription.

Government guidelines for GP in support of patients if you find it difficult/impossible to change brands

gov.uk/drug-safety-update/l...

If a patient reports persistent symptoms when switching between different levothyroxine tablet formulations, consider consistently prescribing a specific product known to be well tolerated by the patient.

academic.oup.com/jcem/artic...

Physicians should: 1) alert patients that preparations may be switched at the pharmacy; 2) encourage patients to ask to remain on the same preparation at every pharmacy refill; and 3) make sure patients understand the need to have their TSH retested and the potential for dosing readjusted every time their LT4 preparation is switched (18).

And here

pharmacymagazine.co.uk/clin...

Discussed here too

healthunlocked.com/thyroidu...

Get bloods retested 6-8 weeks after getting back on your previous brands of Levo

Brandyglass profile image
Brandyglass in reply toSlowDragon

Thank you for your reply I will speak with the doctor. Thankfully I have some of my old meds to tied me over.

SlowDragon profile image
SlowDragonAmbassador

Looking at your (brief) profile info …..you are now only on 50mcg levothyroxine?

You are likely not on high enough dose levothyroxine

Some of your symptoms could be due to inadequate dose levothyroxine

Bloods should be retested 6-8 weeks after each dose change or brand change in levothyroxine

For full Thyroid evaluation you need TSH, FT4 and FT3 tested

Also both TPO and TG thyroid antibodies tested at least once to see if your hypothyroidism is autoimmune

Very important to test vitamin D, folate, ferritin and B12 at least once year minimum

Low vitamin levels are extremely common when hypothyroid, especially with autoimmune thyroid disease and especially if on inadequate dose Levo

About 90% of primary hypothyroidism is autoimmune thyroid disease, usually diagnosed by high TPO and/or high TG thyroid antibodies

Autoimmune thyroid disease with goitre is Hashimoto’s

Autoimmune thyroid disease without goitre is Ord’s thyroiditis.

Both are autoimmune and generally called Hashimoto’s.

Significant minority of Hashimoto’s patients only have high TG antibodies (thyroglobulin)

NHS only tests TG antibodies if TPO are high

20% of autoimmune thyroid patients never have high thyroid antibodies and ultrasound scan of thyroid can get diagnosis

In U.K. medics hardly ever refer to autoimmune thyroid disease as Hashimoto’s (or Ord’s thyroiditis)

Essential to test vitamin D, folate, ferritin and B12

Lower vitamin levels more common as we get older

For good conversion of Ft4 (levothyroxine) to Ft3 (active hormone) we must maintain GOOD vitamin levels

What vitamin supplements are you taking

VERY important to test TSH, Ft4 and Ft3 together

What is reason for your hypothyroidism

Autoimmune?

Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins

Post all about what time of day to test

healthunlocked.com/thyroidu...

Testing options and includes money off codes for private testing

thyroiduk.org/testing/

Medichecks Thyroid plus BOTH TPO and TG antibodies and vitamins

medichecks.com/products/adv...

Blue Horizon Thyroid Premium Gold includes BOTH TPO and TG antibodies, cortisol and vitamins

bluehorizonbloodtests.co.uk...

Medichecks and BH also offer private blood draw at clinic near you, or private nurse to your own home…..for an extra fee

Only do private testing early Monday or Tuesday morning.

Tips on how to do DIY finger prick test

support.medichecks.com/hc/e...

If you normally take levothyroxine at bedtime/in night ...adjust timings as follows prior to blood test

If testing Monday morning, delay Saturday evening dose levothyroxine until Sunday morning. Delay Sunday evening dose levothyroxine until after blood test on Monday morning. Take Monday evening dose levothyroxine as per normal

SlowDragon profile image
SlowDragonAmbassador

In January I was prescribed a higher dosage of Teva. I got palpitations that require a hospital visit. My bloods were fine however I am suffering from mild palpitations now this has been dropped to 50g

How much levothyroxine were you taking before dose was increased

Please add test results from before increase and after dose

TSH, Ft4 and Ft3

If been left long time on too low a dose often necessary to increase VERY Slowly

And definitely don’t change brands …..otherwise you don’t know if issue is brand change or dose change

If need to increase slowly

Eg from 75mcg up (eventually) to 100mcg ….you might need to add 12.5mcg twice a week initially (cutting a 25mcg tablet in half) - giving 87.5mcg twice a week

Wait 6-8 weeks…..then increase by another 12.5mcg 2 days a week…..so on 87.5mcg 4 days and 75mcg 3 days

Wait 6-8 weeks…..then increase to 87.5mcg every day

Wait 6-8 weeks then probably get bloods retested before moving on to increasing further

I ache all over and I am getting muscle and twitches in my hands arms and legs.

Joint pain and aching …..Could be low vitamin D

Pins and needles low B12

Muscle twitches low magnesium

All common when hypo and especially if dose has been reduced

Brandyglass profile image
Brandyglass in reply toSlowDragon

I was on 75 when I was fine had a blood test which indicated it should be raised to 100 and a different brand that's when the issues started. This has now been dropped to 50 and the symptoms have not changed. Will go back to the doctors.

Thank you for the advice.

SlowDragon profile image
SlowDragonAmbassador in reply toBrandyglass

What were your results when on 75mcg

What were results 2-3 months after being on 100mcg

Absolutely essential to test and maintain GOOD vitamin D, folate, B12 and ferritin as well

As you are now only on 50mcg likely increase in hypo symptoms

how long have you been on only 50mcg ?

Brandyglass profile image
Brandyglass in reply toSlowDragon

Only been on it a few days as they first thought 100 was to much I don't have the levels. In my head I think it's the brand not the amount now that could be causing the issues. I'll see what the doctor has to say.

SlowDragon profile image
SlowDragonAmbassador in reply toBrandyglass

how long were you on 100mcg

Dose should never be reduced by 50mcg per day

Suggest you go back on 75mcg if you have enough tablets until you see GP or get new prescription

SlowDragon profile image
SlowDragonAmbassador in reply toBrandyglass

Get hold of all your test results and always keep good records yourself of what dose you were on at each test

Brandyglass profile image
Brandyglass in reply toSlowDragon

👍

judburke profile image
judburke

I too have problems with Teva - it makes my hair fall out.

I have it on my prescription "not Teva" but I now ask the pharmacist to open the bag and check it each time I pick it up as they don't always read that instruction. One time when I got it home it was clearly Teva and I hadn't checked before leaving. The 2nd time they checked and gave me the "Harris" brand mentioned above as its not easily identified that it is in fact Teva when you open the box.

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