I don't think there is much controversy about inadequate iodine intake being an issue.
Plenty of questioning about exactly how much we need, how to test, how we manage iodine intake when taking thyroid hormones, etc. But the basic principle is fairly clear.
When it comes to higher intakes of iodine, there is much, much more controversy. Some practitioners seem to advise intakes of a hundred times the "official" standard requirement of around 150 micrograms a day. Or more.
Personally, I find it stretches my credulity that such high doses are safe and good practice. But that is short of me saying it is definitely not the case.
And we have seen a number of members having issues with high iodine intake in the form of medicines like amiodarone and X-ray/CT contrast agents.
What is clear is that there have been quite a number of papers in the recent past questioning the safety and advisability of "excess iodine". Each paper defines that in its own way. And some papers might simply contain the words and not be relevant. Some papers might even support high doses of iodine.
The search below finds over 32,000 papers but I doubt more than the first few hundred are worth looking through!
This is being posted in the spirit of pointing out some papers exist. And leaving anyone who is interested know of them and to read, if they wish. Beyond my choice of search term, the data is obviously entirely unfiltered. It might include pre-prints, and other lower status papers as well as top quality research papers.
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Excess iodine promotes papillary thyroid carcinoma through the AKT/mTOR pathway
A new LNC89/LNC60-Col11a2 axis revealed by whole-transcriptome analysis may be associated with goiters related to excess iodine nutrition.
Chronic Excess Iodine Intake Inhibits Bone Reconstruction Leading to Osteoporosis in Rats.
Excess Iodine Consumption Induces Oxidative Stress and Pancreatic Damage Independently of Chemical Form in Male Wistar Rats: Participation of PPAR-γ and C/EBP-β.
The Role of Thyroid Hormone Synthesis Gene-Related miRNAs Profiling in Structural and Functional Changes of The Thyroid Gland Induced by Excess Iodine.
Excess iodine exposure acutely increases salivary iodide and antimicrobial hypoiodous acid concentrations in humans.
Protection of Vitamin C on Oxidative Damage Caused by Long-Term Excess Iodine Exposure in Wistar Rats.
Excess Iodine Exposure Acutely Increases Salivary Iodide And Antimicrobial Hypoiodous Acid Concentrations In Humans
SAT-442 The Impact of Chronic Excess Iodine Intake in Adult Mice Behavior
Long-term repetitive exposure to excess iodine induces mitochondrial apoptosis, and alters monoamine neurotransmitters in hippocampus of rats of different genders.
Excess iodine impairs spermatogenesis by inducing oxidative stress and perturbing the blood testis barrier.
Excess iodine intake: sources, assessment, and effects on thyroid function.
Excess iodine-induced lymphocytic impairment in adult rats.
Relationship between excess iodine, thyroid function, blood pressure, and blood glucose level in adults, pregnant women, and lactating women: A cross-sectional study.
Non-immune-related hypothyroidism and its relationship with excess iodine.
Risks of excess iodine intake in Ghana: current situation, challenges, and lessons for the future.
Hypothyroidism in Infants With Congenital Heart Disease Exposed to Excess Iodine.
Effect of excess iodine intake on thyroid on human health.
Consequences of excess iodine.
An investigation into the effects of maternal supplementation with excess iodine on the mechanisms and impacts of reduced IgG absorption in the lamb postpartum.
Effect of Excess Iodine Intake from Iodized Salt and/or Groundwater Iodine on Thyroid Function in Nonpregnant and Pregnant Women, Infants, and Children: A Multicenter Study in East Africa.
A comparative study on the effects of excess iodine and herbs with excess iodine on thyroid oxidative stress in iodine-deficient rats.
Subclinical Hypothyroidism and Elevated Thyroglobulin in Infants with Chronic Excess Iodine Intake.
Effect of excess iodine intake on thyroid diseases in different populations: A systematic review and meta-analyses including observational studies.
The relationship between excessive iodine during pregnancy and adverse pregnancy complications.
Thank you for this information. I did a bit of research when I was “treated” by Sarah Myhill. She insists on everybody taking large doses of iodine but I decided that it is too dangerous a substance to take without good evidence, which I couldn’t find. So I bought the bottle from her but never touched it. I’m glad now, reading the titles of the research papers you found. After all we are receiving iodine everyday in our thyroid hormone tablets.
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