T3 Dosing times

[k8sykes1977]

Hi all,

I recently listened to an excellent podcast from Dr Amie Hornaman about timings and taking thyroid hormone to get the most out of the medication. Ie taking only with water and 1hr each side of eating or drinking anything (other than water). It has triggered me to be much more stringent on taking my meds. I have very poor gut health so will affect absorption at the best of times.

I also believe i have peripheral resistance too but that’s a different story. And I think I need to be taking T3 100% correctly to assess this more

I normally take 3x 40mcg T3 in olive oil capsule compounded by Roseway Labs. but due to all the other medication/supplements I take throughout the day and meal timings, I’m finding it really hard. I’ve even had to resort a few times to taking T3 rectally.

Anyone else taken T3 rectally?

Just wanted to check there’s no issue with taking 2 doses of 60mcg?

I often wake up at 3am to pee so could take a dose then and again at 7am. Do you think that would be ok?

Also Dr Amie Hornamen also said she’s against compounded T3 because she has never seen it work successfully and she always recommends using a normal/generic pharma T3. Anyone else experienced / know of this being correct?

Thanks 🙏🏻

[DippyDame]

The protocol for testing is well known here.

Why do you think you have a form of resistance?

Just asking because I have RTH and need a large dose of T3-only which I take in a single dose at bedtime...that may not suit everyone

I presume you have checked that there are no conflicts with any of the other supplements you are taking, that may be affecting absorption

Resorting to anal dosing seems a tad extreme!

Dosing really depends on what suits us best and gives the best result..often by trial and error.

We also need to be aware of the symptoms of overmedicating

2 doses of 60mcg T3 is a fairly large dose so I assume you understand why you need this amount

I cannot tell you if there might be issues with your dose of 2x60mcg T3 because you haven't explained why/ how you came to this dose

I can tell you, however, that we aim to take the smallest effective dose....not the maximun amount we can tolerate.

Good luck!

[k8sykes1977 in reply to DippyDame]

Thanks for your response. I’m under an excellent endocrinologist. I have history of Lyme, mould, long c’v and a laundry list of other illnesses. I’m definitely in recovery. T3 remains low and remain symptomatic. Zero signs of over medication. Have conversion issues so no good with T4 or NDT. Large dose is needed due to gut issues. We’re trying the liquid t3/olive oil combo to see if absorption improves and to avoid excipients in generic T3. Rectal administration isn’t an issue for me as have progesterone pessaries. Just looking to achieve best absorption.

I take a lot of meds and supplements prescribed by my consultant and these are timed throughout the day. Hence difficult to get the 2hours needed for strict t3 compliance and the rectal route.

Previous consultant suspected THR but did not help with a solution to address this.

I will give it a go doing 2 doses of 60mcg and see if more successful this way. 😃

[SlowDragon Administrator]

3x 40mcg T3 in olive oil capsule

Doesn’t the olive oil impede absorption

Have you tried “ordinary “ T3

[k8sykes1977 in reply to SlowDragon]

I presumed this was a way to improve absorption, especially as it was offered by Roseway, but now I’m not so sure. Will give it a couple months with new dosing until I see my consultant again and then might give generic T3 ago.

Which T3 product is generally better?

[SlowDragon Administrator in reply to k8sykes1977]

Which T3 product is generally better?

Cheapest on private prescription is Thybon Henning 20mcg tablets - £60-£80 per 100 tablets

Lactose and mannitol free. Generally very well tolerated.

Many people cut into 1/4’s to take as 5mcg doses spread through the day

NHS brands 20mcg

Teva - lactose and mannitol free

Morningside - currently difficult to get in many areas of U.K.

Mercury Pharma

[Mobilepirate]

Just saw you got replies and measured your levels, got a bit concerned for a second...

Rectally adminstration of drugs augments a lot absorption... Inot an expert and im seeking for insight regarding my doses, as i take levo and starting T3, i have no thyroid due to thyca.

You should measure your levels, imo you shouldnt do that at all... Its bioavaliable orallly, .. you might end up in the hospital with thyrotoxicosis, i think you're taking to high doses, thyrotoxicosis its a concerning thing that can kill you ..

If you have issues with absorption, i think that If doing this you should lower the ammount due to the fact that rectally adminstration augments a lot absorption of substances.

It seems that limolene or geraniol If mixed with stuff augments absorption, I take limolene and geraniol without issues for some time already, but i dont take It paired with t3 ..you shouldnt use those rectally aswell, might burn specially If not dilluted, sublingually Its fine, and maybe might augment absorption of t3 , not sure, Its an assumption. I guêss that holding sublingually would work, but i think you should try with lower doses instead of holding that ammount of 30 mg sublingually, maybe 5 mg, as It will augment absorption... With selegiline which i dont take the absorption augments 5 times..

Good luck with lyme stuff, i have chronic issues, diffrent but sucks a lot.

[k8sykes1977 in reply to Mobilepirate]

Hi,

thanks for your reply and concerns. I've had thyroid disease for nearly 40 years and very awear of signs to watch out for regarding overmedication and undermedication. Been on t3, with or without t4/NDT for 35 years. The rectal route works fine for me and this is only something I do occassionally when needed to get my dose in and to be away from food and other meds. Since my og post my doc has said rectal delivery is no problem to do. I find 60mcg is too big to do sublingual.

I'm definitely preferring taking 2 doses of 60mcg as easier to manage. Generally dose 1 at 3:30am and dose 2 and 8am. Or 7am and 11:30am.

I will be interested to see how my t3 levels are in Sept when I re do my bloods. And more importantly, how I will be feeling after 6 weeks of a better dosing routine.

Thanks again.