T3 Dosing times

[k8sykes1977]

Hi all,

I recently listened to an excellent podcast from Dr Amie Hornaman about timings and taking thyroid hormone to get the most out of the medication. Ie taking only with water and 1hr each side of eating or drinking anything (other than water). It has triggered me to be much more stringent on taking my meds. I have very poor gut health so will affect absorption at the best of times.

I also believe i have peripheral resistance too but that’s a different story. And I think I need to be taking T3 100% correctly to assess this more

I normally take 3x 40mcg T3 in olive oil capsule compounded by Roseway Labs. but due to all the other medication/supplements I take throughout the day and meal timings, I’m finding it really hard. I’ve even had to resort a few times to taking T3 rectally.

Anyone else taken T3 rectally?

Just wanted to check there’s no issue with taking 2 doses of 60mcg?

I often wake up at 3am to pee so could take a dose then and again at 7am. Do you think that would be ok?

Also Dr Amie Hornamen also said she’s against compounded T3 because she has never seen it work successfully and she always recommends using a normal/generic pharma T3. Anyone else experienced / know of this being correct?

Thanks 🙏🏻

[DippyDame]

The protocol for testing is well known here.

Why do you think you have a form of resistance?

Just asking because I have RTH and need a large dose of T3-only which I take in a single dose at bedtime...that may not suit everyone

I presume you have checked that there are no conflicts with any of the other supplements you are taking, that may be affecting absorption

Resorting to anal dosing seems a tad extreme!

Dosing really depends on what suits us best and gives the best result..often by trial and error.

We also need to be aware of the symptoms of overmedicating

2 doses of 60mcg T3 is a fairly large dose so I assume you understand why you need this amount

I cannot tell you if there might be issues with your dose of 2x60mcg T3 because you haven't explained why/ how you came to this dose

I can tell you, however, that we aim to take the smallest effective dose....not the maximun amount we can tolerate.

Good luck!

[k8sykes1977 in reply to DippyDame]

Thanks for your response. I’m under an excellent endocrinologist. I have history of Lyme, mould, long c’v and a laundry list of other illnesses. I’m definitely in recovery. T3 remains low and remain symptomatic. Zero signs of over medication. Have conversion issues so no good with T4 or NDT. Large dose is needed due to gut issues. We’re trying the liquid t3/olive oil combo to see if absorption improves and to avoid excipients in generic T3. Rectal administration isn’t an issue for me as have progesterone pessaries. Just looking to achieve best absorption.

I take a lot of meds and supplements prescribed by my consultant and these are timed throughout the day. Hence difficult to get the 2hours needed for strict t3 compliance and the rectal route.

Previous consultant suspected THR but did not help with a solution to address this.

I will give it a go doing 2 doses of 60mcg and see if more successful this way. 😃

[SlowDragon Administrator]

3x 40mcg T3 in olive oil capsule

Doesn’t the olive oil impede absorption

Have you tried “ordinary “ T3

[k8sykes1977 in reply to SlowDragon]

I presumed this was a way to improve absorption, especially as it was offered by Roseway, but now I’m not so sure. Will give it a couple months with new dosing until I see my consultant again and then might give generic T3 ago.

Which T3 product is generally better?

[SlowDragon Administrator in reply to k8sykes1977]

Which T3 product is generally better?

Cheapest on private prescription is Thybon Henning 20mcg tablets - £60-£80 per 100 tablets

Lactose and mannitol free. Generally very well tolerated.

Many people cut into 1/4’s to take as 5mcg doses spread through the day

NHS brands 20mcg

Teva - lactose and mannitol free

Morningside - currently difficult to get in many areas of U.K.

Mercury Pharma