Very rapid weight gain, dose increase

[Hippocamp]

Hi all, I first posted a few weeks ago as a new GP prescribed T3 but didn't tell me to start low and slow so I just started with 20mg of Thybon for 2 weeks and felt horrendous (so exhausted). TiggerMe suggested that my T4 wasn't optimal (neither was Vit D, Folate, Ferritin) so I stopped the T3 and upped the T4 to 75mg (from 5 days @50 and 2 days @75). I am probably still under-dosed and will need to up it again to 100mg but was hoping to wait for another 4 weeks to retest and see if vitamins etc also improved as I am supplementing all of them now too.

healthunlocked.com/thyroidu...

The thing is that I still feel unbelievably exhausted and have gone up a dress size or even more in the last 3 or 4 weeks and am putting on weight every day. I have been gluten-free for about 6 weeks now.

I was reading on here that people say that week 3/4 of a dose increase is the worst but with weeks 1/2 being so bad for me I cannot imagine how much worse it can get. Literally none of my clothes fit me. Should I increase to 100mg or start the low dose of T3 or just sit this out for another month and hope that my fatigue starts to improve and the weight gain levels out??

[Incoguto]

I'm sorry you're feeling this way.Your conversion seemed to be poor, based on results of ft4 ft3 in your previous post (ft4 being around 50% and ft3 around 20%). If I were you I'd be trying adding t3 (but not 20 mcg!). You could start with 2.5 t3 and see it goes.

You could also increase t4, but with increasing weight seems like a bad idea? Have you gained weight when you added the 20mcg t3 for a few weeks?

[propervinaigrette]

Sorry to hear about your experience. I also have experienced considerable weight gain. Actually, I'm thinking of trying Wegovy since it seems the weight gain can lead to the need for greater medication, and may be contributing to my candida skin problem, and may also be leading me into a Sjogrens diagnosis. I am going to be looking into Wegovy for weight shortly.

[arTistapple]

I have just had a decent consultation with an NHS endocrinologist (at last) and he explained something that turns out may be very important to me. Just taking more Levothyroxine in the hope it drags up your T3 does just not work for some patients.

In fact the precise opposite can happen.

However the ‘Guidelines’ do not allow GPs to do anything else! Unfortunately it was another NHS who put my Levo up to a degree where I became very ill.

If this works for me (combination therapy) I will be extremely pleased. However I have yet to fulfil the experiment.

It’s great you got T3 but unfortunately doctors know even less about this than they do Levo.

You seem to be making too many changes, too many ‘big’ changes in a very short period of time guided by someone who has not got a clue (ultra common). No wonder you are feeling awful.

Looks like you have had some previous good advice from the Forum. Be still, consider it again and see what else you can work on without upsetting your system any further. It all needs untangling.

Recent blood test results?