Can thyroid S be used under tongue?: Hi all, hope... - Thyroid UK

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Can thyroid S be used under tongue?

DizzyD profile image
12 Replies

Hi all, hope everyone is well.

Usually, i take Efra under tongue and it dissolves pretty quickly. I have ran out of Efra....cannot source them, so now using Thyroid S. Does anyone know if it can be taken under tongue?

Would really apprecciate some feedback

Thank you

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DizzyD profile image
DizzyD
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12 Replies
pennyannie profile image
pennyannie

Hello DD:

The new production and current stock available of Thyroid S has a slightly harder shell coating than prior to 2020 and some forum members have found they can get by crushing or biting the tablet - but it's not as easy as it once was -

I don't have this issue and have always swallowed my NDT as per instructions :

Hopefully others will be around and tell you for sure :

DizzyD profile image
DizzyD in reply to pennyannie

Yes just cut one and it does have hard shell so that rules out any chance of it melting under tongue. How long, before and after eating food, is it best to take NDT?

My gut health is not that great so i am concerned about NTD being absorbed.

pennyannie profile image
pennyannie in reply to DizzyD

Well the general rule is take on an empty stomach and wait and hour before any food or drink other than water -

I have always take mine in the middle of the night at a toilet break around 2-3 am - as I did Levothyroxine :

FallingInReverse profile image
FallingInReverse in reply to pennyannie

Penny - do you know if the patient insert on NDT says to swallow (ie, not designed to be sun-lingual?) just like Levo?

pennyannie profile image
pennyannie in reply to FallingInReverse

Thyroid S is from Thailand and there is no patient insert in any language :

FallingInReverse profile image
FallingInReverse

I have lots of personal experience/input on Levo/T4 and Lio/T3 sublingual.

Why do you want to take yours sublingual?

Also, I know nothing about how NDT might be different.

greygoose profile image
greygoose

All thyroid hormone tablets are designed to be swallowed because

a) they need stomach acid to detach them from the fillers in the pill

b) the molecules are too large to pass the blood/mucus barrier.

If you let it dissolve under your tongue, all that happens is it is slowly swallowed and ends up in the stomach, anyway, it doesn't go directly into the blood as with medication that is designed to be taken sublingually. And if you eat straight after, the risk is that the thyroid hormone will bind with some of the ingredients of what you eat/drink and will be lost. There was a good post about that just recently, but I can't find it.

healthkiwi profile image
healthkiwi

I'm probably not being very helpful but I'm pretty blasé about taking Thyroid-S. I was told many years ago that the faff that's required for taking synthetic Levo is not necessary when using NDT / DTE. NDTs / DTEs are the complete thyroglobulin molecule . That is a complex molecule and has to go through various enzyme and peptide processing steps to release the actual thyroid hormone wrapped within the molecule . So it is broken down and absorbed much further down the digestive tract (and we can't really know what other food may be in process there also .) NDTs/ DTEs therefore are naturally 'slow release' in our system. I think at some time I heard that the hard casing round Thyroid-S is to ensure the thyroid molecules get down to the correct part of the digestive tract before being released / absorbed for use.

I think of it this way: when NDTs were introduced, they were a supplement to replace eating chopped up bits of actual raw thyroid gland which was the earlier treatment - i.e. food. Not a synthetic purified chemical, which is fussy about what other chemicals are present.

Personally my habit is get up, get 3 tablets, crunch a bit then swallow (I don't know why I crunch, it's now just habit ) then have breakfast and lots of coffee. Works for me.....

Susieg1 profile image
Susieg1 in reply to healthkiwi

I take Armour thyroid, I get up, take 1 tablet, crunch it a bit swallow, go to the bathroom then have black tea with milk and a tsp of monkfruit, half an hour or so after I take the Armour thyroid. Do you think this is okay? My TSH is almost nothing, but I don't have any symptoms. My FT3 and FT4 are in range.

healthkiwi profile image
healthkiwi in reply to Susieg1

Sorry, I don't know. I'm only able to tell my own experience. If you have no problems, isn't that OK for you?

Paquita profile image
Paquita in reply to Susieg1

It is said that polyfenols interact with thyroid meds. They are in black tea and coffee. I'm not too strict with this, but you might want to test for yourself if there is a difference.

Paquita profile image
Paquita

It doesn't dissolve, as others have said. I did not have much effect of the latest ones with the harder coating, so I now thoroughly chew the tablets and have more effect now. You can add some dextrose for better absorption.

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