Shytomel duo: Hi guys has anyone heard of or used... - Thyroid UK

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Shytomel duo

Mitch27 profile image
Mitch27
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Hi guys has anyone heard of or used Shytomel NDT? I'm currently on Armour buy it's very expensive and looking fir an alternative. I have previously tried Thyroid S but I'd get bad palpitations on it when I'd need to increase the dose. The best that ever worked was TR Man but unfortunately they stopped producing it 😭😭😭

These are My recent results from my endo who says my dose is "fine" but I don't feel fine πŸ™„

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Mitch27 profile image
Mitch27
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healthkiwi profile image
healthkiwi

Do you mean Cytomel? It's T3 / Lio.

According to the wonderful dopiaza calculator, your FT3 is only 32.43% in range, and your FT4 is in its boots, 10% in range.

No wonder you don't feel "fine"!

Mitch27 profile image
Mitch27 in reply to healthkiwi

Thanks and no not Cytomel. This one is made in India. πŸ™ƒ

Mitch27 profile image
Mitch27 in reply to Mitch27

I can't post the photo of it πŸ™ƒ

healthkiwi profile image
healthkiwi

Ah! Never seen an Indian product mentioned before, but of course they have a huge pharmaceutical industry. Perhaps helvella will know about it.

healthkiwi profile image
healthkiwi

Realised you are asking about SHYTOMEL DUO .I can see it declares similar T4/T3 content as most natural NDTs - 38mcg Levo and 9mcg Lio. Wonder if it's a compounded synthetic, or a natural dessicated extract?

helvella profile image
helvellaAdministratorThyroid UK

UPDATE

I was too focussed on the "Shytomel" and missed the "Duo"!

Levothyroxine 38mcg & Liothyronine 9mcg Tablets

Packaging Size

100 Tablets

Brand

Shytomel Duo 47mg Tablets

Usage/Application

Personal

Packaging Type

Bottle

Ingredient

Levothyroxine 38mcg & Liothyronine 9mcg Tablets

Levothyroxine and Liothyronine (thyroid tablets, USP) for oral use is a natural preparation derived from porcine thyroid glands. They contain both tetraiodothyronine sodium (T4 levothyroxine) and liothyronine sodium (T3 liothyronine) providing 38 mcg levothyroxine (T4) and 9 mcg

The company name appears to be a trader/distributor/exporter rather than manufacturer.

Founded in the year 2016, Kachhela Medex Private Limited is one of the leading Wholesale Trader and Exporter of Alzheimers Medication, Anti Acne Drug and much more.

Will be adding to my Desiccated Thyroid document asap. But information is hard to access.

-----

Shytomel is liothyronine (T3) - not desiccated thyroid.

Appears to be available in dosages of 5, 25 and 100 micrograms.

I have no further information, I'm afraid.

My rest of the world document needs to be updated but the UK and Desiccated Thyroid documents have recently been updated.

helvella's medicines documents (UK and Rest of the World) can be found here:

helvella - Thyroid Hormone Medicines

helvella has created, and tries to maintain, documents containing details of all thyroid hormone medicines in the UK and, in less detail, many others around the world. There is now a specific world desiccated thyroid document.

The link below takes you to a blog page which has direct links to the documents from Dropbox and QR codes to make it easy to access from phones. You will have to scroll down or up to find the link to the document you want.

The UK document contains up-to-date versions of the Summary Matrixes for levothyroxine tablets, oral solutions and also liothyronine available in the UK. Latest updates include all declared ingredients for all UK products and links to Patient Information Leaflets, etc.

helvella.blogspot.com/p/hel...

Mitch27 profile image
Mitch27 in reply to helvella

Thanks a million.. I'm going to order one anyway and see how I get on as it's £20 for 100 as opposed to £220 for Armour..😬I'll keep you updated

helvella profile image
helvellaAdministratorThyroid UK in reply to Mitch27

Please do let me know any further details so I can add to my desiccated thyroid document with accurate information.

And let everyone know how you get ion with it.

Of course, reliability of supply might be an issue. We have seen several desiccated thyroid products come and go over the years. A reliable supply of a decent product at an acceptable price is our holy grail. :-)

Mitch27 profile image
Mitch27 in reply to helvella

They have arrived so I'll start taking them from next week. As you pointed out it's not ndt but contains the same combo t3/t4 so no harm trying it as it was cheap enough. I'll keep you updated πŸ™ƒ

Healthgirl2024 profile image
Healthgirl2024 in reply to Mitch27

I'm having the same problem and saw this Rx on [ redacted source ]. I wanted to try it too. Have you been able to test it yet? Did you like it?

Mitch27 profile image
Mitch27 in reply to Healthgirl2024

I am taking it but haven't had tests yet.. I have added in thyroid s as I was given a bottle.. but still not feeling great. Another lady started taking them as well, will check and see how she is getting on

reikigirl3 profile image
reikigirl3 in reply to Mitch27

Hi Mitch, I am still taking it and feeling fine on it. I have not had a blood test to check T4 or T3 levels yet, but I feel it is working. I have had CFS/ME for 18 years and also now have post covid PoTs too so have fatigue anyway. But I know the feeling of being hypo and I don't have that.

Mitch27 profile image
Mitch27 in reply to reikigirl3

That's good to hear😊 I need to increase my dose and give it a chance as I definitely feel "odd" when taking Thyroid S... what dose are you on ?

pennyannie profile image
pennyannie

Hey there Mitch :

Well that's an unfortunate name - unless I'm pronouncing it wrong !!

So as for your results - how long from your last dose was this blood test and how much Armour do you take - and is this split or you dose once a day ?

Both your T3 and T4 look to be a little low for me -

No thyroid hormone replacement works well until your core strength vitamins and minerals - those of ferritin, folate, B12 and vitamin D are up and maintained at optimal - maybe these need shoring up ?

Mitch27 profile image
Mitch27 in reply to pennyannie

I had been on the dose 6 weeks although had a 4 week break before that as she never got my repeat script to me in time so I was without meds for 4 weeks πŸ™„πŸ™„πŸ™„ I haven't had my ferritin checked recently but last tests in October were OK as this had been quite high ..around 300 previously. Vitamins are OK as I try keep on top of them.

pennyannie profile image
pennyannie in reply to Mitch27

Ferritin can be high because of inflammation which is common if with a thyroid Auto Immune Disease - do you know the reason for your hypothyroidism -

Do you have Hashimoto's ?

Well ideally you need to be on a dose for 6-8 weeks before seeing much improvement in blood tests and blood tests run behind systems by a few weeks - do you feel any improvement ?

Do you track your blood pressure, pulse and body temperature and seen any changes ?

So you dose once a day - at night - so how long was it between last dose and blood draw ?

We generally suggest testing at around 12 hours from last dose - when taking any medication containing T3 -

if this was the case I believe your levels are too low to be optimally medicated.

P.S.

You have tried various brands in the past - how do you see these results compared to those tests taken when you were self medicating ?

Mitch27 profile image
Mitch27 in reply to pennyannie

I left 14 hours between testing. Was always told 15 but that's the time I had to take.I don't remember levels on TR Man but I was pretty hood on it for nearly 2 years and I was having to take 4 grains which I split 2 and 2 morning and night. I literally felt alive on it. Lost 2 stone and just generally felt healthy even though still heavy in weight I felt much much better. I always used to weigh around 60kg until I got hashimoto and weight would go on in stages of about 10kg within about 3-4 weeks... no significant changes in diet... and woukd star like that for about a year then repeat again !!! I'm nose just Iver 100kg and I battle to lose even1kg... I've even contemplated weight loss surgery as I just want yo feel better in myself. I don't want to be skinny.. just less fat πŸ™„ I trued calorie counting, low carbon etc etc but I don't have lots of willpower so find it hard to stick to anything religiously but I do be careful with what I eat. The lethargy is a big part too. And no, no idea what set off the hashimoto... I was on levo for years with low thyroid

pennyannie profile image
pennyannie in reply to Mitch27

Well diets don't work when hypothyroid and under medicated as metabolism is slowed too much and T3 too low to respond in the ' normal ' manner -

Dieting actually down regulates T4 to T3 conversion as the body senses we have gone into starvation mode and holds onto the body fat - and slows down further to preserve ' fat stores ' - is case of famine - as in cave man times.

We do need to consume on a regular basis good fats and calories for good T4 to T3 conversion - so the body receives regular good nutrients to repair and rebuild a strong core strength to support us.

Hashimoto's is an auto immune disease so there is likely a genetic predisposition with someone in your family, possibly a generation away from you with a thyroid health issue

Many forum members find the research of Dr Izabella Wentz helpful - thyroidpharmacist.com

So 4 grains NDT x TR man - would have given you around 36mcg T3 + 152 mcg T4 -

Maybe you would be better on synthetic T3 only - Liothyronine as it would seem to me you are not utilising / converting well the T4 element within the NDT ?

I read the average person needs to find/ convert / make around 50 T3 daily just to function ?

What dose are you currently taking ?

Mitch27 profile image
Mitch27 in reply to pennyannie

Perhaps this is the reason.. I did try t3 once but got terrible hot flushes from it, however might be worth trying again. I have a supply of t3 tiromel from Cyprus. I have read isabella's stories previously. I just get fed up as many out there with advice, including the nice doc on YouTube but can't think of his name..πŸ€” but nothing seems to change for Me. Frustrating. And recently I had a nose op.. as in septoplasty to correct deviated cartilage and that took me 3 months to recover , one infection after another and still not right , then got covid, the bronchitis with laryngitis... and now I have another blood clot.. one thing after another 😭😭😭😭

pennyannie profile image
pennyannie in reply to Mitch27

I'm so sorry - any and all of these issues will have set you back :

We must go low and slow when starting T3 - it's another learning curve and self medicating is not much fun when things do not go to plan as we then get emotional rather than standing back and rethinking.

Was this a fasting blood test and you just had water before the blood draw - even at 14/15 hours these readings would be too low a T3 for me to function well - what dose are you taking ?

Mitch27 profile image
Mitch27 in reply to pennyannie

No not fasting although I'd only had a cup of tea. I'm.on 90mcg

Mitch27 profile image
Mitch27 in reply to pennyannie

I don't split my dose. I take it at night

Mitch27 profile image
Mitch27

Hi All.. my Shytomel has finally arrived from India. I will start taking it in a few weeks when my Armour runs out and let you know how I get on. The name is too funny 🀣

RedApple profile image
RedAppleAdministrator in reply to Mitch27

Not a good idea to wait until your Armour runs out. Try it before you run out, in case it's no good. (Personally the name alone makes me suspicious!).

Mitch27 profile image
Mitch27

🀣🀣 India produce a lot of medications. I checked with my hospital pharmacist before ordering that it's legit 😁

reikigirl3 profile image
reikigirl3 in reply to Mitch27

Hi Mitch, I have just ordered Shytomel too! The Indian pharmacy I ordered it from said it is exactly like Armour. I did ask for a full ingredient's list but they could not give me one. I would really to know what exactly is in it so if you ever find a full ingredients list, please do post it! Also how are you getting on with it? Really hope it is working for you and so glad your hospital pharmacist has given the green light on it too.

helvella profile image
helvellaAdministratorThyroid UK in reply to reikigirl3

Just to point out that there are two products:

Shytomel - which is liothyronine

and

Shytomel Duo which claims to be a desiccated thyroid product.

The company oddly describes this as a 47 microgram product which is the sum of the T4 and T3 content in micrograms. That should be approximately equivalent to 60 milligrams/one grain of most desiccated thyroid products.

You may know this but the possibilities for confusion are great (name, what it is and the available dosage) and I'm thinking about others who may read this thread in the future.

reikigirl3 profile image
reikigirl3 in reply to helvella

Thanks for replying Helvella (sorry only just seen your post), and thank you for pointing this out. My Shytomel Duo arrived yesterday and I am still searching for a full ingredient list. I have always chewed my tablets and this does not taste as pleasant as other I have had. It is a larger flatter white tablet and is harder than my old Thyroid tablet. I feel a little uneasy taking something that I know nothing about, but I will give it a go for a few weeks. I do have some Thiroid S but am not keen on some of the other ingredients in the tablet, but at least I have a back up. So hard when you are doing this on your own! And this has been the only post I have found when searching the internet where somebody is trying it!

helvella profile image
helvellaAdministratorThyroid UK in reply to reikigirl3

Thanks!

Do let me/us know how it goes - and if you get any further information. Obviously I want to put more details in my document!

reikigirl3 profile image
reikigirl3 in reply to helvella

Hi Helvella, I have managed to get a reply from Kachhela Medex Private Ltd. There is no colour agent or coating used and the fillers are starch and dicalcium phosphate. So am hoping that is the full list but who knows! At least it is a start.

helvella profile image
helvellaAdministratorThyroid UK in reply to reikigirl3

Thank you - have put that information into my document.

But it is diabolical that companies don't always make sure this information is in or on every pack!

reikigirl3 profile image
reikigirl3 in reply to helvella

I completely agree, it should be a mandatory requirement

Mitch27 profile image
Mitch27 in reply to reikigirl3

Hi there sorry I seem to have missed these posts 😫 I'm still on them but I do swallow with water, I don't chew them. I've not had any further tests yet but can't say I feel any different 😭 may get a test soon . I feel I probably need a higher dose as I got 90 and that wasn't enough on Armour. I am considering topping up with t3 but no point till I get tested . How long did you wait for delivery as mine took a long time βŒ›οΈ. I am sure there was a list of ingredients in my box but can't find it for love nor money πŸ˜†

reikigirl3 profile image
reikigirl3 in reply to Mitch27

Hi Mitch, no worries at all! I chew mine as read many years ago that if you have gut problems, then chewing in the mouth helps absorption. You could try this if you are not feeling any different? I will get a test done in a few months and see how I am. I must admit I am feeling ok at the moment switching onto them, so they must be similar to the Thiroyd ones I was taking. Mind you it has only been 5 days but I am sure I would feel awful if they were not working. I take 2 1/4 grains every day. [edited by admin] they took a fortnight to arrive. Mine are in a plastic bottle and not a box. Honestly, good luck with taking them and finding the right dose.

Mitch27 profile image
Mitch27 in reply to reikigirl3

Thanks I got the 90mg ones and only taking one a day do maybe u should increase them. I can't remember who I got them fro. But cost me Β£40 ,Β£20 for the tablets 20 postage ..which is fine except taking so long πŸ™„πŸ™„πŸ™„ I know I can get lower doses so might try 90+50 πŸ€·β€β™€οΈπŸ€·β€β™€οΈ

reikigirl3 profile image
reikigirl3 in reply to Mitch27

Mine were cheaper, I got 100 1grain tables for Β£15. I did order them with some other meds as have long covid so my order came to Β£65 with free postage although think the postage is factored in. If you get a pill cutter, you could cut a 90 tablet in half or a quarter and see how you go. And I have had no problems with[edited by admin] and ordered from them a few times now and it always takes 13 or 14 days to arrive so quite reliable.

Mitch27 profile image
Mitch27 in reply to reikigirl3

Thanks a mil.. I've literally just notice the dose is 47 mcg not 90... I'm thinking 90 as Armour was 90...πŸ€¦β€β™€οΈπŸ€¦β€β™€οΈπŸ€¦β€β™€οΈ so I definitely need to increase my dose! It does state its generic Armour .. I'll order 2 bottles next time... πŸ€ͺ I've just been seen Mt long covid clinic as im very breathless since having vovid 18 months ago...

helvella profile image
helvellaAdministratorThyroid UK in reply to Mitch27

The dose of Armour is NOT 90 micrograms. It is 90 milligrams. Because it is the mass of Thyroid USP powder - not the actual thyroid hormone content.

One grain of Armour (60 mg) contains levothyroxine (T4) 38 micrograms and liothyronine (T3) 9. Therefore, one and a half grains/90 mg contains T4 - 57 micrograms and T3 - 13.5 micrograms.

You need to be very careful.

The Shytomel Duo bizarrely adds the T4 and T3 content, in micrograms, as if they are the SAME substance.

60 milligrams (one grain) contains 38 micrograms of T4 and 9 micrograms of T3.

The company oddly describes this as a 47 microgram product which is the sum of the T4 and T3 content in micrograms.

In summary:

If you were on one and a half grains/90 milligrams of Armour, you would likely need around one and a half grains/90 milligrams of Shytomel Duo. With just a very small adjustment, if needed, if that seems slightly too much or too little.

Mitch27 profile image
Mitch27 in reply to helvella

Thank you for clearing that up.. its beyond confusing πŸ˜• 😐 πŸ€¦β€β™€οΈ the annoying factor is I feel better on Armour but the cost is a lot and I definitely know I need a higher dose than 90 according to My last results from the thyroid experts but not the Endo of course... and if the dose goes up so fies the price to around Β£240.. I know it's for 3 months supply but it's still such a lot in one go 😒

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