Blood test results : Repeated blood tests ordered... - Thyroid UK

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Blood test results

Bluenose69 profile image
17 Replies

Repeated blood tests ordered by my GP trying to compare private ones I had a month ago with different ranges,I had both done at 9am and only glass of water can someone help please?

12th February 2024 repeat GP tests January 2024 Medichecks private test

B12 344 range (187-883.00ng/L B12 active 60. 37.5- 150 pmol/L

Folate 7.4 ug/L (3.10-20.50 ug/L. Folate 7.17. 3.89-26.8 ug/L

TSH 3.3 muL. (0.4-4.90 ). mu/L. TSH 4.76. 0.27-4.2 mlU/L

*GP said these are normal* *Medichecks red flagged Thyroid*

My cholesterol was high said I need to go on statins.

Thank you

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Bluenose69 profile image
Bluenose69
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SlowDragon profile image
SlowDragonAdministrator

Medichecks full thyroid results Feb 2024

TSH 4.76 range 0.27-4.2

Free T4 (fT4) 13.6 pmol/L (12 - 22) 16.0%

Free T3 (fT3) 3.9 pmol/L (3.1 - 6.8) 21.6%

Obviously very low

You need BOTH TPO and TG antibodies tested

Meanwhile

Work on improving low B12 and folate

Low B12 symptoms

b12deficiency.info/signs-an...

methyl-life.com/blogs/defic...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a separate B12 supplement

A week later add a separate vitamin B Complex 

Then once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.

If Vegetarian or vegan likely to need ongoing separate B12 few times a week

Highly effective B12 drops

natureprovides.com/products...

Or

B12 sublingual lozenges

uk.iherb.com/pr/jarrow-form...

cytoplan.co.uk/shop-by-prod...

B12 range in U.K. is too wide

Interesting that in this research B12 below 400 is considered inadequate

healthunlocked.com/thyroidu...

Low folate

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

healthline.com/nutrition/fo...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule)

Thorne currently difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

Igennus B complex popular option too. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose

Post discussing different B complex

healthunlocked.com/thyroidu...

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg) and continue separate B12

Post discussing how biotin can affect test results

healthunlocked.com/thyroidu...

helvella.blogspot.com/p/hel...

greygoose profile image
greygoose

12th February 2024 repeat GP tests January 2024 Medichecks private test

B12 344 range (187-883.00ng/L B12 active 60. 37.5- 150 pmol/L

You can't compare a serum B12 with an active B12 result. They're not testing the same thing.

Folate 7.4 ug/L (3.10-20.50 ug/L. Folate 7.17. 3.89-26.8 ug/L

Not a lot of difference, but both too low. Folate should be in double figures, at least over mid-range.

TSH 3.3 muL. (0.4-4.90 ). mu/L. TSH 4.76. 0.27-4.2 mlU/L

Were both tests done at the same time of day?

Are you on thyroid hormone replacement? If so, you need an increase in dose. There is a slight difference, but neither of them are 'normal'. What he means is, they're in the normal range. But still too high. Should be around 1.

*GP said these are normal* *Medichecks red flagged Thyroid*

My cholesterol was high said I need to go on statins.

No, you don't need to go on statins. Hypos shouldn't go on statins because the side-effects are worse for hypos. And women shouldn't take them, anyway. They lower your sex hormones.

What you need is your FT3 tested - didn't you have that done with your Medichecks test? I bet it's too low. High cholesterol is a hypo symptom, not a disease that needs drugs.

Bluenose69 profile image
Bluenose69 in reply togreygoose

Here are the he last three tests over the past year with Medichecks different range for B12 and folate.I was also told by them that my red cells appear enlarged.My mother had under active thyroid.

February 2023 January 2024 February 2024

TSH 2.95 T3 4. TSH 3.19 T3. 3.42. TSH. 4.76. T3. 3.9

B12 active 56(37.5-188) B12 active 60 (37.5-150)

Folate 15.9(8.83-60.8). Folate 7.17(3.89-26.8)

greygoose profile image
greygoose in reply toBluenose69

The ranges are regulated by the machine that the lab uses for the assay. If they change machines, the range changes too. But, if you work out the percentages through the range of your results, you'll probably find they're more or less the same.

What are the ranges for the T3?

Bluenose69 profile image
Bluenose69 in reply togreygoose

The ranges for T3 are. 3-1 to 6-8 4.1-6.8 3.1-6.8

I have never been treated for a thyroid issue and because of this I was wondering if this could have a detrimental effect on my health.Also can you have large blood cells if you have an under active thyroid please.?

TiggerMe profile image
TiggerMeAmbassador in reply toBluenose69

Large blood cells common with hypo's

Bluenose69 profile image
Bluenose69 in reply toTiggerMe

Thank you I really am so confused my GP says in normal range but you lovely people say it’s not.Do you think I should have the antibodies test please?

TiggerMe profile image
TiggerMeAmbassador in reply toBluenose69

Your TSH has been increasing over the years which suggests that your thyroid is under attack or could just be failing... if you look at your Medichecks results you will likely see that you have had your antibodies tested..

These are my results as I have Ord's (no goitre) whereas my Sister and Brother aren't showing any antibodies yet both have failing thyroids

Was your Mothers referred to as Hashimoto's?

If you know it's autoimmune then often changing your diet can help, gluten or dairy free, the hormone replacement you receive is the same

Antibodies results
greygoose profile image
greygoose in reply toBluenose69

I really am so confused my GP says in normal range but you lovely people say it’s not.

GPs don't understand ranges, and they don't know that 'in-range' is not the same as 'euthyroid' or 'optimal'.

Yes, it's in what is laughingly called the 'normal range', you don't have to spend seven+ years in med school to see that. But it's where within the range that the result falls that counts. A TSH of over 3 is technically hypo. But, because the range goes up to 4+ doctors think 3+ has to be 'normal'. It isn't. A truly euthyroid TSH would be around 1.

To better understand ranges - and maybe share with your doctor - have a look at this article:

The normal range: it is not normal and it is not a range

ncbi.nlm.nih.gov/pmc/articl...

DippyDame profile image
DippyDame

GP needs to go back to med school!

These results are not optimal...forget the word "normal", it means nothing and is an unhelpful conclusion

No need for statins!

You are hypothyroid/ undermedicated hence high cholesterol...and possibly other symptoms

thyroiduk.org/signs-and-sym...

I suspect your vit D is still too low...needs to be at least 100nmol/L but ideally closer to 150 for hypos.

Supplement with vit D + vitK3....the K3 helps ensure the calcium in the system goes to the hard tissues ( bones and teeth) rather than to soft tissues causing blood vessel calcification.

Bluenose69 profile image
Bluenose69 in reply toDippyDame

Thank you for your help and advice I’m not on any medication for Thyroid or B12 could this be why I ache all over especially bones and joint pain.?My vitamin D is 75.

DippyDame profile image
DippyDame in reply toBluenose69

Yes!

The following labs show that you are hypothyroid

Diagnostic test( ie before medication) TSH should be close to 2.....even 1.

At 4.76 you are hypothyroid with very low thyroid hormone levels as is evidenced by the labs below

Both Frees should be approaching 75% through their respective ranges.....not 16.0% and 21.6%!!

VitD, vit B12, folate and ferritin ....greygoose has explained this. These nutrients need to be optimal to support thyroid function. You need to raise your levels with good supplements

Medichecks results Feb 2024....copied from SlowDragon's post above

TSH 4.76 range 0.27-4.2

Free T4 (fT4) 13.6 pmol/L (12 - 22) 16.0%

Free T3 (fT3) 3.9 pmol/L (3.1 - 6.8) 21.6%

We always advice that antibodies TG and TPO are tested at least once to check for thyroid autoimmune disease/ Hashimoto's

Your GP needs to prescribe Levothyroxine...starting dose 50mcg, test again after 6/8 weeks on a steady dose.

Repeat test and increase by 25mcg until symptoms resolve.

This should help -

thyroiduk.org/if-you-are-un...

See a GP again explain why you think you are hypothyroid ( using info provided in this post) and including your list of symptoms ... see checklist in the above link.

Make a note of all you wish to say/ ask it acts an an aide memoir

You may need to be politely insistent!

With correct medication you should feel much better.

Good luck!

Bluenose69 profile image
Bluenose69 in reply toDippyDame

Thank you so much I always remember my mom saying she felt like a hypochondriac before she was finally diagnosed with hypothyroidism that’s exactly how I feel now hopefully with your knowledge and help I can get help.Our GP’s in the Uk don’t seem to know much about B12 and Thyroid they go by the numbers and not the symptoms I’ve heard this so much on these forums.

Sparklingsunshine profile image
Sparklingsunshine in reply toBluenose69

Yes doctors have turned into little more than call centre staff, reading stuff off computer screens all day. Blood tests are all these days, symptoms have very much taken a back seat.

DippyDame profile image
DippyDame in reply toBluenose69

You're welcome

Forgot to refer to large red blood cells

nhs.uk/conditions/vitamin-b...

I still feel like a hypochondriac if I have to speak to medics....after decades!

I have a form of thyroid hormone resistance and need high dose T3 which I self medicate....I'm sure my GPs think I travel by broomstick!!

The lack of knowledge re thyroid disease is staggering.

And... if they insist on treating by TSH this is your argument against that -

thyroidpatients.ca/2021/07/...

Please keep us posted. We're all in this thyroid mess together so just ask us if you need help.

Bluenose69 profile image
Bluenose69 in reply toDippyDame

Hi I went to see my GP and showed her the print outs from what you said.Also included the thyroid TSH,T3 results from Medichecks showing a rise in my TSH.No matter what I said she said we have to go by NHS guidelines and my recent blood test shows TSH 3.3 and normal .I tried nicely to explain what you had said about large blood cells and high cholesterol could possibly due to thyroid issues.She said well you need to go back to Medichecks and get them to treat you.I can’t do that I’ve only got a pension so fed up x

DippyDame profile image
DippyDame in reply toBluenose69

Good grief....but not surprising!

No wonder you are fed up.

Her response that you need to go back to Medichecks for treatment smacks of sarcasm

Can you see another GP?

In your shoes I would be making a complaint to the Practice Manager at the surgery....put it in writing!

You feel unwell, you did not get a fair hearing, the GP's response was insensitive and unhelpful and left you feeling depressed.....er, NO, don't mention depressed, they'll just give you antidepressants!!!

You feel, in addition to the lab results, that your lived experience/symptoms makes you a reliable witness to the condition which is making you unwell

You provided evidence that you are hypothyroid/ undermedicated

You wish an appointment with another GP who is knowledgeable about thyroid disease.

They forget ( or don't know) that symptoms are a recognised part of diagnosis .

she said we have to go by NHS guidelines

Perhaps this GP needs to read and understand the following NHS guidelines, and learn to use informed professional judgement rather than relying on a list of numbers!

Guidelines inform clinical practice but don’t dictate it. They do not replace clinicians’ knowledge and skills. Doctors are expected to be familiar with nationally recognised guidelines that are relevant to their specialty, as well as local guidelines. This does not mean they cannot depart from guidance when they consider it to be in the patient’s interests to do so.

bmj.com/content/350/bmj.h84....

Good luck!

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