I am on Levothyroxine (also Liothyronine). I found that in the first years of taking it, I gained weight (about 10kg). I’ve since learned from this forum that that was almost certainly because I was on the wrong dosage. I am in the process of addressing that and I think it’s helping.
Do you have some recent blood tests (with ranges)you could share?
Also, there’s a search function on the forum and you will find lots of posts discussing exactly this problem.
I stacked 20kg with Levo and felt like I'd been run over by a truck for 4 years on Levo. Once I sorted out dosage and a few do's and don'ts I returned to normal weight with NDT. (Natural Desiccated Thyroid). That was 7-8 years ago.
If you go to NDT. Start on a starter dose like 60mg per day. Don't calculate an NDT dosage by converting current Levo and T3 dosage . Always start low and ease your way into NDT. Very easy to over do it, feel great for 3 days , OD and then your world falls apart and everyone blames NDT. You could stay on 60mg forever and you wont die. So start on 45 or 60 and then in 2 months try 75, or even 90. Slowly optimize. You drive NDT by how you feel and not blood tests. You need less in summer and more in winter. Less if you are sitting around, more if you are active or playing sport. You can pull NDT caps apart or cut a Thyroid-S pills with an old school razor blade, to optimize dose.
I took Euthyrox for 3 years. For a while it was fine but probably because my FT3 and FT4 were fine. When I started gaining weight and also had other symptoms of hypothyroidism, my blood tests showed that I was not converting T4 to T3 well. So my endo told me to try Novothyral, which is also from Merck and has both T4 and T3 and that has helped, including with the weight gain.
I live in Switzerland and have been hypo since the birth of my daughter in 2010. I managed to lose and stabilize my weight. I took euthyrox for about 9 years, until Merck changed the formula. My endo suggested that I change to Tirosint- the worst thing I have ever done. I ballooned, almost literally! My hair fell out, my skin became dry, I looked about 8 months pregnant, the list goes on. I eventually figured out that Tirosint was the culprit and changed back to Euthyrox about 18 months ago. I am only just starting to feel myself again!
This is my story, but I have friends who feel great on Tirosint.
I started levothyroxine at 150mcg in 2016 and my weight didn’t change. In March ‘22 I reduced to 125mcg as an endocrinologist added T3 at 10mcg 3 times a day (total 30mcg). At the time I didn’t realise this was a massive starting dose. I lost 7kg over the next 12m and Hv now stablised. I didn’t Hv the weight to lose and now look far too thin.
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