I was started on a trial of 5mcg T3 alongside 75mcg T4 four weeks ago due to being highly symptomatic and having a poor conversion rate. My TSH was 0.87 and now it’s 3.6.
Do I keep the T3 at 5mcg and increase my T4 to 100mcg. Or as I’m feeling better on the T3 do I increase my t3 to 2x 5mcg doses throughout the day and stay on 75mcg T4.
Thankyou for any advice, I can’t get hold of my GP.
Sam x
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Sammy333
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Do you have blood results with ranges to share? We can really only go by those.
Get tested after you have been on a stable dose for 6-8 weeks, longer is better. Be sure to test with the recommended protocol.
Recommended blood test protocol: Test at 9am (or as close as possible), fasting, last levo dose 24hrs before the blood draw, last T3 dose 8-12 hours before blood draw & no biotin containing supplements for 3-7 days (Biotin can interfere with thyroid blood results as it is used in the testing process)? Testing like this gives consistency in your results and will show stable blood levels of hormone and highest TSH which varies throughout the day. Taking Levo/T3 just prior to blood draw can show a falsly elevated result and your GP/Endo might change your dose incorrectly as a result.
What supplements are you taking?
5mcgs T3 is a pretty small amount so its likely that will need to be increased.
You said you have been on T3 for 4 weeks. It takes 6-8 weeks for blood levels to stabilise, so you need to retest in 2 weeks at the earliest for an accurate result.
Now that you are on T3 you have to get an FT3 result as TSH becomes irrelevant of dosing correctly. Taking T3 often suppresses TSH.
Follow protocol advised by SlowDragon for the blood test.
obviously the questions and replies from others are things you need to sort, but my remark is - you might find 25mcg too large a reduction for just 5mcg of T3 added.
See how everything goes, but you might need to take 5mcg T3 twice a day or add a little levo back (100, 75 on alternate days).
Not saying this is correct for you, but it’s what I needed. Am well aware that we are all different though.
Making sure all vits and minerals are good as recommended is very important.
I think I am missing something. Since her T4 was close not even close to the top of the range, why would it be reduced? Wouldn't it make more sense to keep the T4 the same and just add a little T3 and go from there? It seems like this will add to the confusion of what works and what doesn't work.
we don't know what fT4 was before it was reduced, it may have been at top of range then .. but even if it wasn't , Endo will just be following the guidelines they are given for starting combination therapy . nearly all guidelines say "reduce levo by 'x'....and replace with 'x' T3... with very little consideration given to where fT4 is in range.
Their main interest is keeping TSH in range, so they reduce Levo as a matter of course because they know adding T3 will lower TSH.
If they were using their own brains , then yes , they wouldn't necessarily need to reduce Levo unless T4 was high in range.... but they are not encouraged to use their own brains.
Yes I was reduced to 50mcg levo as I added in more T3 which made me feel super unwell :/ Iv popped a new post up with all recent reports and what my levels where before t4 supplementation x
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