Hi my pharmacist has managed to get supplies of mercury 50mg levothyroxine. I had been on these for 5 years. But recently they had not been available, so had to change to accord. Have been taking accord now for fours months. And doing ok. My pharmacy now has the mercury and I changed back. But started feeling really off after changing back. With headaches and dizzyness. Has anyone ever experienced this with swopping suppliers. Thankyou
Change of levothyroxine suppliers: Hi my... - Thyroid UK
Change of levothyroxine suppliers
Many of us notice differences between makes. At one point, I was in a similar position to you and decided to go with Accord rather than Mercury Pharma. There wasn't a huge difference for me, but definitely something.
Also, Accord has been more reliably available in the years since.
Relatively few of us do well on a dose as low as 50 micrograms.
I suggest that the change of make might be revealing a continuing under-dosing. Would very much like to see you getting re-rested - TSH and FT4 and FT3 (if possible).
Thank you, doctor phoning me today. Going to ask for blood test to be done. Did seem alot better with accord
The cost of another prescription, so you can switch back to Accord is trivial (the GP time and dispensing fees being more than the cost of the medicine). So ask for at least that.
All the best.
How long have you been left on just 50mcg levothyroxine
When were thyroid and vitamin levels last tested
ALWAYS test thyroid levels early morning and last dose levothyroxine 24 hours before test
Essential to test vitamin D, folate, ferritin and B12 at least once a year
If under medicated on inadequate dose levothyroxine, vitamin levels tend to drop
Low vitamin levels tend to lower TSH
Essential to test Ft4 and Ft3 ….not just TSH
Bloods should be retested 6-8 weeks after each dose change or brand change in levothyroxine
Hi have been on 50mg levothyroxine for about 5years. I have my bloods done if I feel a bit off. They were done about 3month ago. And came back satisfactory. Just a week after having supplier change. I have been having dizzyness in the morning since changing suppliers. GP thought I may had labyrinthitist. But my ear checked out fine. Wondered if the levo meds could cause this. Thankyou
Guidelines on dose levothyroxine are quite clear
GP should increase dose levothyroxine slowly upwards until Ft4 is near top of range and all symptoms gone
Most important results always Ft3 (at least 50-60% through range)
all four vitamins need testing at least annually and maintain at OPTIMAL levels
Being under medicated for thyroid frequently causes low stomach acid levels and poor nutrient absorption, leading to low vitamin levels
OPTIMAL vitamin levels are
Vitamin D at least over 80nmol
Serum B12 at least over 500
Folate and ferritin at least half way through range
Dizziness is frequently low B12
What vitamin supplements are you currently taking
Typical daily dose levothyroxine is 1.6mcg per kilo per day
So unless very petite, likely to need to increase dose SLOWLY upwards in 25mcg steps until on at least 100mcg levothyroxine per day
Hi, which vitamin should I be taking. Having my bloods done next week Thankyou
Am I meant to be taking any vitamin tablets too. Dr never suggested any in 5 years.
Yes GP should test vitamin D, folate, ferritin and B12 at least annually
When hypothyroid we frequently develop LOW stomach acid. This leads to poor nutrient absorption and low vitamin levels
Low vitamin levels tend to lower TSH (all a GP often, inappropriately looks at)
On levothyroxine we MUST have GOOD vitamin levels
EXTREMELY Common on levothyroxine to need to supplement vitamin D and vitamin B complex virtually continuously to maintain OPTIMAL vitamin levels
Approx how old are you
Low vitamin levels are more common as we get older
Low vitamin levels very common if left under medicated
Thyroid levels
They were done about 3month ago. And came back satisfactory
please add actual results and ranges
ALWAYS get actual results and ranges on all blood tests
Always test thyroid levels early morning and last dose levothyroxine 24 hours before test
I have been having dizzyness in the morning since changing suppliers.
Many people find different brands of levothyroxine are not interchangeable
But more likely just needing dose increase in levothyroxine
Approx how much do you weigh in kilo
Levothyroxine doesn’t “top up “ failing thyroid…it replaces it. Essential to be on high enough dose
Typically dose levothyroxine is increased slowly upwards in 25mcg steps until on approx 1.6mcg per kilo per day
A few people need less, some need higher dose
pathlabs.rlbuht.nhs.uk/tft_...
Guiding Treatment with Thyroxine:
In the majority of patients 50-100 μg thyroxine can be used as the starting dose. Alterations in dose are achieved by using 25-50 μg increments and adequacy of the new dose can be confirmed by repeat measurement of TSH after 2-3 months.
The majority of patients will be clinically euthyroid with a ‘normal’ TSH and having thyroxine replacement in the range 75-150 μg/day (1.6ug/Kg on average).
The recommended approach is to titrate thyroxine therapy against the TSH concentration whilst assessing clinical well-being. The target is a serum TSH within the reference range.
……The primary target of thyroxine replacement therapy is to make the patient feel well and to achieve a serum TSH that is within the reference range. The corresponding FT4 will be within or slightly above its reference range.
The minimum period to achieve stable concentrations after a change in dose of thyroxine is two months and thyroid function tests should not normally be requested before this period has elapsed.