se thyroid peroxidase AB cono blood test 1000.... - Thyroid UK

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se thyroid peroxidase AB cono blood test 1000.0 ku/l

Beeclare profile image
16 Replies

hi i have had a blood test taken on 19 july and my thyroid test has come back as 1000.0 ku/l dose this mean i have an overactive thyroid again as i had an overactive thyroid in 2014.

i have recently been diagnosed with ADHD and I’m taking medication could this have caused my thyroid to become overactive?

clare

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Beeclare
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SlowDragon profile image
SlowDragonAdministrator

High thyroid antibodies confirms autoimmune thyroid disease also called Hashimoto’s

Hashimoto’s frequently starts with transient hyperthyroid results and symptoms (possibly what you had previously…..it’s not really overactive…..but as cells in thyroid breakdown, excess thyroid hormones can be temporarily released)

Hashimoto’s will eventually become increasingly hypothyroid as thyroid is attacked and destroyed

About 90% of primary hypothyroidism is autoimmune thyroid disease

Have you had TSH, Ft4 and Ft3 levels tested

Always test thyroid levels early morning, ideally before 9am

Also important to test vitamin D, folate, ferritin and B12

ADHD and Hashimoto’s may be linked

ceril.net/index.php/articul...

healthcentral.com/article/i...

Beeclare profile image
Beeclare in reply to SlowDragon

These are my results Plasma C reactive protein

2.4 mg/L

Se thyroid peroxidase Ab conc

1000.0 ku/L

Serum FSH level

23.4 iu/L

Serum LH level

12.0 iu/L

Serum TSH level

0.01 mu/L

Serum ferritin

268.0 ug/L

Serum free T3 level

9.6 pmol/L

Serum free T4 level

22.7 pmol/L

Serum estradiol level

279.0 pmol/L

SlowDragon profile image
SlowDragonAdministrator in reply to Beeclare

Can you add range on Ft4 and Ft3 results

Request GP test

Vitamin D

Folate

B12

TSI or Trab antibodies for Graves’ disease

Autoimmune hyperthyroid disease

Beeclare profile image
Beeclare in reply to SlowDragon

Last time i had an overactive thyroid I was told I have Graves’ disease and A goitre. I was on Carbimazole medication for 8 months before I had allergic reaction and had to stop they then tested me regularly every month for 6 months and said that the thyroid was back to normal. The consultant at the hospital said it normally takes 12 to 18 months before you can come off the medication and they were most surprised that after only 8 months I was all clear.

I am looking at my blood test results on my my GP app and there are no ranges on there.

I had the blood test on Tuesday and GP called on Friday to say you need to get an appointment asap but we don’t have any today

So i am going to call in the morning to get an appointment x

greygoose profile image
greygoose in reply to Beeclare

That really does sound more like Hashi's than Grave's. Trouble is, very few doctors know the difference, as strange as that may sound! And as soon as they see a low/suppressed TSH leap to the conclusion that it has to be Grave's and put the patient on carbi WITHOUT DOING THE PROPER TESTING! Which is wrong, and very unprofessional, but they just don't have the knowledge to treat thyroid correctly.

If you had Hashi's, and took carbi, your FT4/3 levels would have gone down very quickly, and you would become hypo. So, the fact that you came off the carbi after six months only, really does suggest that it was Hashi's, and not Grave's. But, your doctors were too dim to put two and two together.

Now, your antibodies are high, and so are your FT4/3, but not high enough to suggest Grave's. Those levels really do suggest a Hashi's 'hyper' swing. They will eventually come down by themselves and you will probably become hypo. :)

Beeclare profile image
Beeclare in reply to greygoose

Hi thanks for your reply I don’t know anything about Hashimoto is there medication that can help ? X

greygoose profile image
greygoose in reply to Beeclare

The only thing you can do is replace the thyroid hormones when your thyroid becomes too damaged to make them itself. There is no treatment or cure for Hashi's, I'm afraid.

SlowDragon profile image
SlowDragonAdministrator in reply to Beeclare

Look through old test results on app

See if you can find TSI or Trab antibodies test results

If not been tested, insist GP does test this week

As greygoose said ….we see a small, but steady stream, of initially hyper Hashimoto’s patients misdiagnosed as having Graves’ disease if Graves antibodies aren’t tested …..including Buddy195 , one of admin team on here

It’s also possible (but rare) to have Graves’ disease and Hashimoto’s at the same time

Beeclare profile image
Beeclare in reply to SlowDragon

I have looked and can’t see TSI or TRAB on my blood tests. My Serum free T3 level

9.6 pmol/L

19 Jul 2022

5.1 pmol/L

17 May 2021

My Serum free T4 level

22.7 pmol/L

19 Jul 2022

13.4 pmol/L

17 May 2021

10.9 pmol/L

6 Jul 2020

11.4 pmol/L

21 Sep 2018

11.9 pmol/L

3 Jul 2017

13.1 pmol/L

3 Mar 2016

14.1 pmol/L

28 Sep 2015

20.9 pmol/L

My Serum TSH level

0.01 mu/L

19 Jul 2022

2.71 mu/L

17 May 2021

2.13 mu/L

6 Jul 2020

3.22 mu/L

21 Sep 2018

1.66 mu/L

3 Jul 2017

0.63 mu/L

3 Mar 2016

0.51 mu/L

28 Sep 2015

0.51 mu/L

13 jan 2013

0.01 mu/L

Is there any other results that could help just ask x

SlowDragon profile image
SlowDragonAdministrator in reply to Beeclare

Obviously you need to know the ranges on these results

(Should be Figures in brackets after each result)

Predominately Ft4 is low ….This STRONGLY suggests Hashimoto’s, not Graves’ disease (assuming you weren’t taking Carbimazole)

Beeclare profile image
Beeclare in reply to SlowDragon

Thanks for your reply. Is there anything i can do as i have been struggling to sleep i spent most of my time tossing and turning 4 week of not much sleep is exhausting me I also have been having hart palpitations and I feel sick most of the day. I am seeing my GP at 3:30 should I ask to be referred to endocrinology ? X

SlowDragon profile image
SlowDragonAdministrator in reply to Beeclare

What dates were you taking Carbimazole

Request GP test

Vitamin D

Folate

B12

TSI or Trab antibodies for Graves’ disease (Autoimmune hyperthyroid disease)

Are you currently taking any Carbimazole or propranolol (beta blocker) ?

Beeclare profile image
Beeclare in reply to SlowDragon

Hi i am not on any meds yet the HP have referred me to endocrinology on Friday last week and I’ve been told I have a 2 to 3 week wait. I have asked fir blood test and on the form it say bone Profile vitamin D folate vitamin B12

I also got the GO to print the Results and I now have the ranges so

Free T3 is 9.6 pmol/L 2.40-6.00pmol/L

Thyroid peroxidase Ab conc > 1000.0 ku/L 0.00- 5.60 ku/L

Serum TSH <0.01 mu/L 0.35-5.00 mu/L

Free T4 22.7 pmol/L 9.00- 22 pmol/L

Serum ferritin 268 ug/L 10.00-200.00ug/L

Thanks for all your advice x

SlowDragon profile image
SlowDragonAdministrator in reply to Beeclare

So if not on any medication these results suggest Hashimoto’s

Very high thyroid antibodies suggests Hashimoto’s rather than Graves’ disease. It’s also possible to have mildly raised TPO antibodies with Graves’ disease

I have relaid these results out by date

Not sure if I have correct results on correct date …it was confusing

19 Jul 2022

TSH 0.01 mu/L ( 0.35-5.00 )

Ft4 22.7 pmol/L (9 -22) only just over range

Ft3 9.6 pmol/L (2.4-6.0) High

Likely a temporary Hashimoto’s flare as thyroid breaks down

17 May 2021

TSH 2.71 mu/L ( 0.35-5.00 )

Ft4 13.4 pmol/L (9 - 22)

Ft3 5.1 pmol/L (2.4 - 6.0)

6 Jul 2020

TSH 2.13 mu/L ( 0.35-5.00 )

Ft4 10.9 pmol/L (9 - 22)

21 Sep 2018

TSH 3.22 mu/L ( 0.35-5.00 )

Ft4 11.4 pmol/L (9-22)

3 Jul 2017

TSH 1.66 mu/L ( 0.35-5.0)

Ft4 11.9 pmol/L (9-22)

3 Mar 2016

TSH 0.63 mu/L ( 0.35-5.0)

13.1 pmol/L (9 - 22)

28 Sep 2015

TSH 0.51 mu/L ( 0.35-5.0)

14.1 pmol/L (9-22)

13 Jan 2013

TSH 0.51 mu/L ( 0.35-5.0)

Ft4 20.9 pmol/L (9-22)

Beeclare profile image
Beeclare in reply to SlowDragon

Thanks for your reply can i ask why is the TSH so low <0.01 the range says (0.35-5.00)Whats dose this mean ? X

SlowDragon profile image
SlowDragonAdministrator in reply to Beeclare

TSH 0.01 mu/L ( 0.35-5.00 )

Ft4 22.7 pmol/L (9 -22) only just over range

Ft3 9.6 pmol/L (2.4-6.0) High

Because Ft3 is over range

TSH is the message from pituitary to tell thyroid to work

Because you have (temporary) excess hormones, probably due Hashimoto’s, pituitary is not sending any messages to thyroid

This temporary excess thyroid hormones is called a Hashimoto’s flare. Caused by sudden breakdown of cells in thyroid releasing excess thyroid hormones.

After each flare thyroid becomes a little more damaged and increasingly hypothyroid

Read about Hashimoto’s here

thyroiduk.org/if-you-are-hy...

thyroidpharmacist.com

drhedberg.com

The main problem is medics frequently just look at low TSH…..assuming it’s Graves’ disease (autoimmune HYPERTHYROID)

Your results suggest Hashimoto’s

It’s possible but rare to have Hashimoto’s and Graves at same time.

To confirm Graves’ disease GP or endocrinologist must test TSI or Trab antibodies

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