Should I or shouldn't I decrease Levothyroxine? - Thyroid UK

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Should I or shouldn't I decrease Levothyroxine?

saritadelmar profile image
18 Replies

Below are the results of my TSH, FT4, and FT3 from a blood draw on July 6, 2022. It was drawn before 9 am and that was 26 hours after the last morning dose of my daily dose of 75 mcg of Levothyroxine and 5 mcg of Liothyronine.

TSH, 0.14 L -- 0.40 - 4.50 mIU/L

Free T4, 1.3 -- 0.8 - 1.8 ng/dL

Free T3, 3.1 -- 2.3 - 4.2 pg/mL

My Endo asked me to lower only my Levo by skipping one dose of it once a week. She said the TSH is too low. I feel fine, other than some palpitations that I have experienced for years.

I am open to any comments and suggestions. Thank you in advance!

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saritadelmar
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18 Replies
SeasideSusie profile image
SeasideSusieRemembering

Saritadelmar

If you feel fine there is no need to change anything. Your TSH is going to be low because you take T3, that's just what it does. FT3 is well within range so you are not overmedicated. Why change anything just to satisfy a number that your endo wants to see?

saritadelmar profile image
saritadelmar in reply toSeasideSusie

What are the symptoms of overmedication? How does it affect the heart when overmedicated? Thanks in advance

FancyPants54 profile image
FancyPants54 in reply tosaritadelmar

You aren't over medicated with those results. And you feel fine, so that's another big indicator that you are not over medicated.

For me, over medication makes my resting heart rate go up a bit (it's harder to tell for me because I have an arrhythmia that gives me a high and irregular rate anyway, but I can see a different trend if I'm taking too much medication. I am also miserable, have loose bowels and terrible fatigue. The fatigue is in my limbs, and in my head. I am good for nothing.

saritadelmar profile image
saritadelmar in reply toFancyPants54

Thank you for the detailed response on symptoms of overmedication. Could your arrhythmia be caused by your dosage? I have an arrhythmia and the cardiologist said it could be caused by dosage, but he doesn't get involved with changing anything like my Endo. Certainly is a complicated matter. I should probably share these posts with my Endo, she has known I am influenced by this forum, and usually is respectful. I'll ask her what her opinion is about the low TSH not being a problem as long as T4 and T3 are within range and that I am feeling well. I am curious now what she will say about it. Thanks for sparking my thoughts.

FancyPants54 profile image
FancyPants54 in reply tosaritadelmar

My Afib long proceeded me using any kind of thyroid hormone. So no, it's not caused by T3. Too much T3, over range T3 and too little, low or below range T3, can cause Afib. Doctors only seem to have heard about the "too much" scenario and they don't understand how to measure it properly, 12 hours after a dose, and they don't know how to interpret the bloods.

TSH was invented to help diagnose hypothyroidism, it was never meant to be used to monitor doses. If you take any T3 medication, you need to closely monitor your FT3 level.

Buddy195 profile image
Buddy195Administrator

Forum advice is to ensure that last Levothyroxine dose is 24 hours before the blood draw and last dose of T3 is 8 hours before. Next time you test do remember to split your T3 the day before your test (eg take 2.5mcg Lio 16 hours before the test and 2,5mcg Lio 8 hours before the test).

Taking T3 often suppresses TSH so your endocrinologist should take this into account and look at FT3/ FT4 levels. If you feel well and these are within range, I would not consider reducing your Levothyroxine.

saritadelmar profile image
saritadelmar in reply toBuddy195

Thank you for the reminder to split the T3 and last dose 8 hours before the test.

SlowDragon profile image
SlowDragonAdministrator

Also, when were vitamin D, folate, ferritin and B12 levels last tested

What vitamin supplements are you currently taking

Do you have autoimmune thyroid disease (hashimoto’s)

Are you on strictly gluten free diet

saritadelmar profile image
saritadelmar in reply toSlowDragon

I am strictly gluten-free and have Hashimotos.

The following were tested on the same day as TSH etc., July 6. I only take a 2,000 to 4,000 IU of vitamin D3 supplement (not always regularly) and once in a great while B-Complex.

Ferritin -- 56 -- 16-288 ng/nL

Vit B-12 -- 402 -- 200-1100 pg/mL

Folate, serum 8.4 -- ng/mL reference range Low 3.4 -5.4, Borderline 3.4- 5.4, Normal 5.4

Vit D -- 25-OH -- 20-30

Thank you for any comments on these!

SlowDragon profile image
SlowDragonAdministrator in reply tosaritadelmar

Sorry, what’s your vitamin D result

B12 and folate could be better

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

chriskresser.com/folate-vs-...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Thorne Basic B or Jarrow B Right are recommended options that contains folate, but both are large capsules. (You can tip powder out if can’t swallow capsule)

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate methyl folate supplement and continue separate B12

Low B12 symptoms

b12deficiency.info/signs-an...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a B12 supplement as well as a B Complex (to balance all the B vitamins) initially for first 2-4 months.

once your serum B12 is over 500 (or Active B12 level has reached 70), stop the B12 and just carry on with the B Complex.

B12 sublingual lozenges

amazon.co.uk/Jarrow-Methylc...

cytoplan.co.uk/shop-by-prod...

healthunlocked.com/thyroidu...

How other member saw how effective improving low B vitamins has been

healthunlocked.com/thyroidu...

Ferritin better at least over 70

Look at increasing iron rich foods in your diet

saritadelmar profile image
saritadelmar in reply toSlowDragon

Thank you for all the info, I'll be studying all of this.

My Vit D results are:

Vitamin D Status 25-OH

Vitamin D range:

Deficiency: <20 ng/mL

Insufficiency: 20 - 29 ng/mL>

Optimal: or + 30 ng/mL

Thank you in advance for any comments on these results.

SlowDragon profile image
SlowDragonAdministrator in reply tosaritadelmar

Sorry ….should have realised, you’re not in U.K.

Vitamin D, aiming to improve to 40ng/ml in USA units

(that’s 100nmol in U.K. units)

How much vitamin D are you currently taking

jimh111 profile image
jimh111

Leaving 26 hours since the last L-T3 dose will give false fT3 and TSH figures. However, you take so little L-T3 it will make negligible difference.

Reducing your L-T4 by 1/7 will make a small difference, you could try it to keep your endo on board but I get the impression they are fiddling around to justify their salary.

saritadelmar profile image
saritadelmar in reply tojimh111

The Endo fears I will be thrown into Afib by T3 because I mentioned palpitations. The small amount of T3 I take has actually lessened my palpitations. Thank you for your thoughts.

FancyPants54 profile image
FancyPants54 in reply tosaritadelmar

That's absolute nonsense! Take it from one who lives with permanent Afib. My Afib is worse if my T3 drops too low. The heart needs T3. These endos know so little about this. It's not right.

saritadelmar profile image
saritadelmar in reply toFancyPants54

Wow, that's encouraging. Do you mind my asking your dosage? And do you have an idea of the actual cause of your Afib? Once in a great while my heart speeds to 140 a minute but doesn't last more than an hour. A heart monitor picked up the recurring fast beats that usually are no longer than 11 beats. Happens a few times during the night.

FancyPants54 profile image
FancyPants54 in reply tosaritadelmar

I probably inherited my Afib. Dad had it, so did at least one brother and sister of his and one of his brother's children. Mine was not kicked off by anything in particular when it was still spasmodic events.

I am currently on 45mcg T3 and 25mcg Levothyroxine. But I'm a long standing work in progress trying to get my thyroid hormone to actually reach the cells and do their job.

saritadelmar profile image
saritadelmar in reply toFancyPants54

Thank you for giving me some background history. Helps when comparing others with ourselves. I hope you find your perfect "spot."

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