Hey! I have subclinical hypo and hashi (tpo 124) i have been on levo 3 months trying to get it under 2,
It was 3.3 - 4 weeks ago, 5.5 originally in January. My dose was upped to 75mg and i have another test in 2 weeks.
My Vit D was low end in January and i have been supplementing for almost 3 months.
B12 was also top end of 300 so also been taking b12 and b complex aswell as folate, selenium and lots of diet changes.
i ovulate each month confirmed by bbt and a blood test, how can this be stopping me getting pregnant if i am ovulating ?
I cant find anything online that explains other than it disrupts ovulation which isnt the problem for me so is it really this thats impacting my fertility?
I know nobody tell me what the problem is but i am trying to understand why all the research/info just states it impacts fertility through preventing ovulation (which isnt always the case)
Thanks
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Nat2021
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You don’t need any obvious gut issues at all to still find gluten free diet reduces symptoms and many, many Hashimoto’s patients find it slowly reduces TPO antibodies
Poor gut function with Hashimoto’s can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.
According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but a further 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal
Before considering trial on gluten free diet get coeliac blood test done FIRST just to rule it out
If you test positive for coeliac, will need to remain on gluten rich diet until endoscopy (officially 6 weeks wait)
If result is negative can consider trialing strictly gluten free diet for 3-6 months. Likely to see benefits. Can take many months for brain fog to lift.
If no obvious improvement, reintroduce gluten see if symptoms get worse.
The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported
In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned
Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.
You can ovulate and not get pregnant due to reasons such as PCOS or low sperm count, but if you've only been medicating Levo for 3 months then hormones and system axes are more likely still levelling.
The complex hormonal interplay usually allows scope of small variations in healthy women but for those who have experienced larger deficiencies/elevations there’s a journey back to a normalised communication with the pituitary gland. Also long term hormonal imbalance can result in issues such as loss of progesterone receptor site sensitivity for example, or follicle sensitivity to FSH, just as thyroid hormone levels represent only blood levels and not cellular which could be deficient.
If TSH rises with corresponding prolactin then levels of much needed LH for egg release can become suppressed, which also discourages the high progesterone levels required to prepare the uterus lining for the fertilised egg. You also need enough FSH to secrete enough oestrogen in a negative feedback loop so the egg can be implanted, whilst too much oestrogen risks elevated TBG binding too much thyroid hormone and that TSH rising again.
Also regarding Hashimotos, there are members who say thyroid antibodies don’t matter because they are only there to mop up mess created by prolific WBC’s attacking the thyroid gland, but their presence makes many unwanted changes in our body, namely inflammation. Because of the further immune changes naturally instigated in pregnancy or even by our monthly 28 day cycle, this Hashi inflammation can become troublesome and even influence conception and retention of pregnancy by elevating TH cells (helper cells in first line defence).
Therefore, you need to be patient as hormones & system axes readjust back to normalised patterns which can take many months, whilst keep building good nutrient/iron levels and reducing bodily inflammation (elevated thyroid antibodies). And keep positive as you have made some amazing changes so far. You just need everything to respond rightly to that wanted falling TSH.
Good luck 🤞
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T Helper (Th) Cell Profiles in Pregnancy and Recurrent Pregnancy Losses: Th1/Th2/Th9/Th17/Th22/Tfh Cells
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