I got the shock of my life this morning when the lab sent via email a test result. It shows that I have a testosterone level of 81 (range 3-67). I placed a call to my Endo and she agreed a woman my age (63) should not have testosterone levels that high.
Just think all I had planned to discuss with her were the muscle aches and neuropathy I’m experiencing from Tirosint-Sol and Tirosint. Now going down a totally new diagnostic tree. Additional have high Basophils and low Neutrophils.
For Informational purposes: I sent this question to a Second Opinion Endocrinologist at a renown hospital and this is the reply I received.
“I see that your total testosterone is high, but that the free testosterone is normal. This could be due to your recent thyroid hormone excess, which causes the liver to make more Sex Hormone Binding Globulin (SHBG), which is the protein that carries testosterone around in blood. I recommend that the total and free testosterone levels be rechecked in another two months to see if this does not resolve with restoration of normal thyroid status. You should probably also bring this to the attention of your gynecologist.”
Mmm. I think that’s a stretch. Yes, improving thyroid hormone levels would raise testosterone but not to that extent—certainly not to a level that would exceed that found in a pre-menopausal woman. And reading back through previous posts, I can’t see that your thyroid hormone levels have been particularly high in recent months. How high did they go?
There could be something else going on—an adrenal issue potentially or ovarian cyst.
My levels in Feb were out of bound. TSh was .019 , T4 was 2.0, but of course T3 was not optimal and I have a lot of Reverse T3 (28) I believe. I have ovarian cysts that yes I must look into. I now do not have good blood glucose controls and the endo won’t prescribe anything to support.
Found this information. Unfortunately for me, adding T3 may have caused more liver damage.
Have you ever had your cortisol levels checked?
I’m also wondering, giving your collection of symptoms, whether you have a pituitary issue.
24 hr Free Cortisol was 191 out of 65-200. Metabolized Cortisol was 2414 where it should have been between 2750-6500.
My last cortisol check was Dec 2020 and was low in morning. Pregnanediol, Estone, Estradiol, DHEA was below leuteal range and Testosterone 4.39 (2.3-14) on a Dutch Test.
Hi Liel Not saying you do have but google polycystic ovaries. My daughter, wife and mother inlaw have - hence why I know anything .
2. High blood sugar
According to the journal Diabetes Metabolism Research and Reviews, women with high blood sugar levels of type 2 diabetes have higher chances of high testosterone. When insulin increases it can stimulate the ovaries to produce testosterone, especially in women with PCOS. So, to lower your testosterone level naturally, keep your blood sugar level in check.
Testosterone HRT with Levothyroxine 
High DHEA sulfate- any experience?
Help with teenage son with high T3
Low testosterone with thyroid antibodies
2 years post-thyroidectomy - Struggling with Tirosint and finding the right dose
