Another blood test, just more questions! - Thyroid UK

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Another blood test, just more questions!

Yoll profile image
Yoll
8 Replies

Here are the latest results taken as per guidelines on this site. They seem fine to me, of course the TSH is very low which always alarms the GP.

I take 100 mcg Levo and 15mcg Lio

I was on 75mcg Levo and was moved to 100mcg on trial basis.

I have lost a lot of the digestive issues I have had for years since on T3 and I had lost my insomnia but since I have been on 100mcg I now have one very bad night in 4. Which is manageable but frustrating.

Should I stay on a 100mcg? or do alternated days 100/75 and see if that help?

Does this blood test tell me that I don't have Hashimoto's?

It does look like I need to up my Vit D but I wasn't taking any supplements when I had the test.

What should optimal Folate results be??

Thank you for all for always being so helpful

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Yoll
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8 Replies
SeasideSusie profile image
SeasideSusieRemembering

Yoll

Should I stay on a 100mcg? or do alternated days 100/75 and see if that help?

You can try, when on combination hormone replacement it's all about gradual tweaking of individual doses to find your sweet spot. However, lowering your dose of Levo is likely to lower your FT4 level and it's already quite low. Some of us on combo replacement are fine with low FT4 as long as FT3 is in the upper part of it's range, some of us need both FT4 and FT3 fairly well balanced in the upper part of their ranges to feel well, it's just something we have to find out for ourselves.

Does this blood test tell me that I don't have Hashimoto's?

Is it your first antibody test? If you've had antibodies tested before and they were over range then you have Hashi's, and because antibody levels fluctuate then a lower level another time doesn't mean that you don't have Hashi's. But if this is your first antibody test then both TPO and Tg levels are low and don't suggest Hashi's, but it is possible to have Hashi's without raised antibodies.

It does look like I need to up my Vit D but I wasn't taking any supplements when I had the test.

It's a pretty good level at 95.4nmol/L, the Vit D Society and Grassroots Health both recommend a level of 100-150nmol/L with a recent blog post on Grassroots Health recommending at least 125nmol/L. If you want you could supplement during the winter months at maybe 2,000iu D3 daily (plus D3's important cofactors - magnesium and Vit K2-MK7) then retest at the end of March to see if you need to adjust the dose, continue or stop for the summer months.

What should optimal Folate results be??

Folate is recommended to be at least half way through it's range. Medichecks range is 3.89-19.45 so you're looking at 12 plus with that range.

Yoll profile image
Yoll in reply toSeasideSusie

Thank you for such a prompt reply.

All my symptoms get mixed up with the menopause symptoms so I never know which is one it the culprit! I have started a little hormone replacement , but having had breast cancer my GP is not too keen , so the t4/ t3 combo has helped in many areas and not in others, started in June 2021. may be I'll try a bit more T4. Body weight ratio 100mcg should have been OK.

In Aug 2020 TgAB -12 TgOab - 100. Retested in Feb 2021- by the NHS ENDO didn't ask for TgAB just did TgOab which was 31 didn't ask for T3 either!!! If it isn't Hashimoto's going gluten free wouldn't help! I have never been able to get an answer to the Hashimoto's!

As my exGP said " we only treat the symptoms, not the cause of these symptoms" what a mad way to go about things

I will go back on my B12 +Folate and D3 +K2. Magnesium I hesitate as it was well above range the last time I checked.

Thank you for your help

SeasideSusie profile image
SeasideSusieRemembering in reply toYoll

Yoll

Body weight ratio 100mcg should have been OK.

I wouldn't take too much notice of that. We need what we need. The amount of Levo (only) based on weight is an estimate for a starter dose of Levo when first diagnosed, in some cases, to be adjusted as necessary.

In Aug 2020 TgAB -12 TgOab - 100

Do you mean TPO antibodies (thyroid peroxidase) were 100? We usually see the range for TPO antibodies either <34 or <60, so it may well be that those were over range which confirms Hashimoto's, the fact that they're lower now doesn't mean you don't have Hashi's, once over range then you have Hashi's regardless of any other results at a later date because antibodies fluctuate, that's the nature of Hashi's.

If it isn't Hashimoto's going gluten free wouldn't help!

It might, you could be gluten intolerant or gluten sensitive, trying a gluten free diet might help and it might not.

I have never been able to get an answer to the Hashimoto's!

Your GP or endo wouldn't be bothered anyway, they tend to dismiss antibodies and all it means is that the cause of your hypothyroidism is autoimmune, the immune system attacks the thyroid and gradually destroys the thyroid. Hashi's isn't treated, it's the resulting hypothyroidism that is, so the treatment will be the same. It's just that with Hashi's then it's likely that as and when the antibodies fluctuate so will symptoms and test results, you can go from stable to a false hyper state then swing back to hypo or stable again.

As my exGP said " we only treat the symptoms, not the cause of these symptoms" what a mad way to go about things

Well, that's sort of right with hypothyroidism. Whether it is autoimmune (Hashi's) or primary hypothyroidism, the thyroid doesn't work properly so doesn't produce enough thyroid hormone ergo symptoms of hypothyroidism. The only thing that can be done is to replace the missing natural thyroid hormone with synthetic thyroid hormone and the symptoms of hypothyroidism should resolve once optimally medicated.

Magnesium I hesitate as it was well above range the last time I checked.

Testing magnesium is unreliable. About 99% of magnesium is stored in bone, muscles and soft tissues, leaving about 1% in the blood. So testing what's in the blood isn't giving an accurate picture of our magnesium status.

A red cell magnesium test is the better indicator of magnesium status, not the standard serum magnesium test.

If you want to read the science, this information is from this article:

ncbi.nlm.nih.gov/pmc/articl...

SlowDragon profile image
SlowDragonAdministrator

How long have you been on 100mcg levothyroxine

Do you always get same brand levothyroxine at each prescription

If anything, you might want a slight INCREASE in levothyroxine…..perhaps 112mcg twice week initially…..retest in 6-8 weeks

Yoll profile image
Yoll

I was on 100mcg for year (Northstar) then I when private and was started on T3 and reduced the T4 to 75mcg . then was asked to go back to 100mcg for 6 weeks trial, which I found very hard to do as every time I had digestive issues, so I stopped. Now I have manage the 6 weeks the digestive issues have disappeared, but the insomnia has return 1 night out of 4 so not as bad as before but not as good as with 75mcg. which really confuses me.Add to that menopause symptoms and you have a bag of worms.

I'll try and stay on 100mcg and add 12mcg twice a week . I'm hoping I'll get there in the end!

Thank you for your help

Moog77 profile image
Moog77 in reply toYoll

This is interesting. You found the increase from 75mcg to 100mcg tough? But persevered?

Yoll profile image
Yoll in reply toMoog77

well ! Yes, it sounds mad but I wasn't sure if it was the medication or the food I was eating as it was over the summer and I was eating out or with friends which doesn't always agree with me! so it was all trial and error in the end it paid off as my digestion is great at the moment

Moog77 profile image
Moog77 in reply toYoll

I'm struggling with the same increase but I'm on t4 only. Feel worse before feeling better I think. Seems to be par for the course!

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