Elevated TPO and gamma globulin

[Miraclesky]

My son' blood test showed high thyroid TPO. Does it mean he has hashimoto? Does hashimoto always lead to hypothyroid ?

His blood test also showed high gamma globulin. Is there a correlation between high TPO and high gamma globulin ?

Thanks in advance.

[SeasideSusie Remembering]

Miraclesky

Raised TPO antibodies suggest Hashimoto's. Hashi's is where the immune system attacks and gradually destroys the thyroid which eventually leads to hypothyroidism. How long it takes isn't really predictable. Treatment wouldn't be offered until the raised antibodies are accompanied by a TSH showing over range (but not necessarily reached 10 which is when Primary Hypothyroidism is diagnosed) or if FT4 goes below range.

Some members with Hashi's have found that adopting a strict gluten free diet can help, although there is no guarantee.

Gluten contains gliadin (a protein) which is thought to trigger autoimmune attacks so eliminating gluten can help reduce these attacks.

You don't need to be gluten sensitive or have Coeliac disease for a gluten free diet to help.

Gluten/thyroid connection: chriskresser.com/the-gluten...

some information about Hashi's:

stopthethyroidmadness.com/h...

stopthethyroidmadness.com/h...

hypothyroidmom.com/hashimot...

thyroiduk.org.uk/tuk/about_...

Supplementing with selenium l-selenomethionine 200mcg daily is said to help reduce the antibodies, as can keeping TSH suppressed.

Hashi's and gut absorption problems tend to go hand in hand and can very often result in low nutrient levels or deficiencies. It's essential to test Vit D, B12, Folate and Ferritin and address any problems. You are welcome to post these results, including reference ranges (plus units of measurement for Vit D and B12), for comment and suggestions for supplementing where necessary.

I'm afraid I can't help with the high gamma globulin.

[Miraclesky in reply to SeasideSusie]

Thanks SeasideSusie, that's very helpful. Sorry to ask another question : Can hashi go into remission ?

[SeasideSusie Remembering in reply to Miraclesky]

Miraclesky

Can hashi go into remission ?

I don't have Hashi's so I can't answer from experience, but symptoms and test results fluctuate with Hashi's. How and when the immune system attacks the thyroid is pretty random so you can have periods of stability (rather than remission) then maybe a false "hyper" episode when the attack causes thyroid hormone to be released, then after that you will be a bit more hypothyroid as a bit more of the thyroid would have been destroyed. There will come a point where the thyroid has been destroyed enough to cause hypothyroidism then that is it, the thyroid wont then be able to produce enough hormone itself and replacement hormone (Levothyroxine) will be needed and as the thyroid can't regenerate replacement hormone is for life.

If you look to the right of the page (on a PC, probably scroll down on another device) you will se TOPICS and one of those is HASHIMOTO'S with over 3,000 posts. It might be worth having a look through some of those as well as the links I gave previously.

[Miraclesky in reply to SeasideSusie]

Thanks for the explanation

[greygoose]

Can hashi go into remission ?

I don't know if you can call it 'remission' as such, but you can have a prolonged period of euthyroidism in between a hyper phase and going back to hypo. That's often when people claim to have 'cured' or 'reversed' their Hashi's by whatever means. But, it doesn't last.

[Miraclesky in reply to greygoose]

Thanks

[SlowDragon Administrator]

He needs FULL thyroid and vitamins tested

For full Thyroid evaluation need TSH, FT4 and FT3 plus both TPO and TG thyroid antibodies tested.

Also EXTREMELY important to test vitamin D, folate, ferritin and B12

Low vitamin levels are extremely common, especially with autoimmune thyroid disease (Hashimoto’s or Ord’s thyroiditis)

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water .

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins

List of private testing options

thyroiduk.org/getting-a-dia...

Medichecks Thyroid plus antibodies and vitamins

medichecks.com/products/adv...

Blue Horizon Thyroid Premium Gold includes antibodies, cortisol and vitamins by DIY fingerprick test

bluehorizonbloodtests.co.uk...

Thriva Thyroid plus antibodies and vitamins By DIY fingerpick test

thriva.co/tests/thyroid-test

If you can get GP to test vitamins and antibodies then cheapest option for just TSH, FT4 and FT3

£29 (via NHS private service ) and 10% off down to £26.10 if go on thyroid uk for code

thyroiduk.org/getting-a-dia...

monitormyhealth.org.uk/

NHS easy postal kit vitamin D test £29 via

vitamindtest.org.uk

If TPO or TG thyroid antibodies are high this is usually due to Hashimoto’s (commonly known in UK as autoimmune thyroid disease).

About 90% of all primary hypothyroidism in Uk is due to Hashimoto’s. Low vitamin levels are particularly common with Hashimoto’s.

Gluten intolerance is often a hidden issue too

Link about thyroid blood tests

thyroiduk.org/getting-a-dia...

Link about Hashimoto’s

thyroiduk.org/hypothyroid-b...

List of hypothyroid symptoms

thyroiduk.org/if-you-are-un...

[Miraclesky in reply to SlowDragon]

Thanks