Results at first glance seem a bit contradictory as to whether TSH rises or falls with fluoxitine,... but there is clearly an acknowledged association with thyroid function , even if it's quite small..
" Patients with normal thyroid function who were treated with fluoxetine demonstrated a significant reduction of T(3) after 15 and 30 days of treatment (p = 0.034 and p = 0.011) and a significant reduction of T(4) throughout the intervention period (p = 0.04 after 15 days; p = 0.015 after 30 days; and p = 0.029 after 90 days). However, all thyroid parameters remained within the euthyroid range."
Given that you have TPOab, and they are monitoring your TSH every 6 months.. i think it's likely that lower T3 /4 will not help you feel better than you do now.
So do a lot more reading before you agree to take it, because since you are currently stuck waiting for your TSH to rise enough for a diagnosis , if it did lower your TSH , it will just mean it takes longer to get diagnosed.
(having said that, since you are nowhere near getting diagnosed at the moment , i suppose it's possible that it might help with depression, you wouldn't know unless you tried it...But before you do, at least get GP to acknowledge that it may affect your TSH.)
Also it was in the news recently that NHS have now acknowledged that Antidepressant's can be hard to withdraw from.
Hi thank you for a detailed reply. I had no idea it could lower TSH levels.
I don't really want to ask my gp about that to be honest. I think i know the response. 'Don't worry about that, there's nothing wrong with your thyroid'
It was actually a rheumatologist that recommended the 6 monthly tests via gp based on high antibodies. I think if it was up to the gp they wouldn't bother.
Trust me, if the GP didn't want to bother, they wouldn't agree to testing 6 monthly , regardless of who suggested it . They are testing every 6 months because they Know that you are more likely than some one without significant high TPOab to become hypothyroid at some point.( >1000 is significant) This is not a matter of GP opinion .. it's a matter of fact..... one that even the NHS acknowledge and have put in their recent thyroid diagnosis and treatment guidelines. So he may say "there's nothing wrong with your thyroid" and that may be true at the moment.. but he's supposed to be keeping an eye on your TSH in case it goes up .. so whether there is anything wrong with your thyroid at the moment is irrelevant to that.
And prescribing something that may affect what he's supposed to be monitoring is something he should be aware of.
Hopefully he already is aware if it , but there 's no harm in you checking he is ... in fact it would be daft not to.
So don't let them make you feel stupid / or a nuisance for pointing it out if you want to.
Discuss it , he'll then have to write something about what was discussed in your notes... If you don't discuss it , your notes will just say "prescribed antidepressants" and it will say that forever , which will not help with getting prescribed levo if your TSH does go slightly over range ... The next GP will see "antidepressants" and think .. oh but this lady was depressed before so that is probably all that is wrong with her now, so even though her TSH is a bit over range i still don't think it's her thyroid that's the problem.
So .. be a nuisance .. make then write something like .. "she has agreed to try flouxitine but was concerned it may affect her TSH"
Crikey ...i've just realised it's "prozac"Did they discuss with you how careful you have to be to come of this really slowly due to withdrawal effects ?
I haven't done enough reading to find a good bit to send for notes .. but as far as i know, anything you send them on paper has to be put in your notes.. so even a hand written note that said "Dr Doctor x , i am concerned that taking 'x' could affect my TSH and may delay any future diagnosis of hypothyroidism" would end up in there.
There is a shopping list in my NHS notes , cos i'd written points to raise with Doctor on the back ... GP asked if she could keep it to remind her.... years later i discover both sides of note were scanned into NHS notes .... Reminders of my symptoms on one side .. Onions /Post Office /Gas Bill /Bog Roll , on the other lol
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.