Hi All, Thanks for the replies, I have now had a blood test done with Medichecks, please could someone look and tell me what I should do now. They show that 3 of the tests are outside of the range, can anybody tell me what these mean, thanks. I did the blood test first thing in the morning before taking any medication, also I am at the moment on 125mg of Levothyroxine.INFLAMATION- 0.6 mg/l (Range 0-5)
IRON STATUS- 115 ug/L (Range 30-400)
VITAMINS- Folate- Serum - 6.0 Range more than 2.9
VITAMIN B12-ACTIVE - 107 pmol/L (Range 25.1-165)
VITAMIN D- 77 nmo/L ( Range 50-200)
THYRIOD HORMONES
TSH -4.75mlU/L ( Range 0.27-4.2) *
FREE T3 4.5pmol/L ( Range 3.1-6.8)
FREE THYROXINE - 14.7pmol/l Range 12-22
AUTOIMMUNITY.
THYOGLOBULIN ANTIBODIES 760.0 IU/mL ( Range 0-115)
Ferritin is recommended to be half way through range so with that range it would be 215. However, I have seen that a good level for a male is 150.
Eating liver once a week will help raise ferritin level, or liver pate, black pudding and other iron rich foods. No more than 200g liver per week due to it's high Vit A content.
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VITAMINS- Folate- Serum - 6.0 Range more than 2.9
This is a bit low. The range is 2.9-14.5 and folate is recommended to be half way through range so that would 9+ so you could make sure you eat lots of folate rich foods.
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VITAMIN B12-ACTIVE - 107 pmol/L (Range 25.1-165)
I always think Active 12 over 100 is OK.
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VITAMIN D- 77 nmo/L ( Range 50-200)
The Vit D Society and Grassroots Health recommend a level of 100-150nmol/L.
To reach the recommended level from your current level, you could supplement with 2,500-3,000iu D3 daily.
Retest after 3 months.
Once you've reached the recommended level then you'll need a maintenance dose to keep it there, which may be 2000iu daily, maybe more or less, maybe less in summer than winter, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. You can do this with a private fingerprick blood spot test with an NHS lab which offers this test to the general public:
Doctors don't know, because they're not taught much about nutrients, but there are important cofactors needed when taking D3.
D3 aids absorption of calcium from food and Vit K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems such as hardening of the arteries, kidney stones, etc.
D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds if taking D3 as tablets/capsules/softgels, no necessity if using an oral spray.
For D3 I like Doctor's Best softgels as it's a good, clean supplement with no excipients, just D3 and extra virgin olive oil to aid absorption, some people use BetterYou oral spray as it's absorbed through the mucous membranes but it does have a lot of excipients
For Vit K2-MK7 I like Vitabay or Vegavero brands.
Magnesium helps D3 to work. We need Magnesium so that the body utilises D3, it's required to convert Vit D into it's active form. So it's important we ensure we take magnesium when supplementing with D3.
Magnesium comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds if taking magnesium as tablets/capsules, no necessity if using topical forms of magnesium.
Don't start all supplements at once. Start with one, give it a week or two and if no adverse reaction then add the next one. Again, wait a week or two and if no adverse reaction add the next one. Continue like this. If you do have any adverse reaction then you will know what caused it.
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THYRIOD HORMONES
TSH -4.75mlU/L ( Range 0.27-4.2) *
FREE T3 4.5pmol/L ( Range 3.1-6.8)
FREE THYROXINE - 14.7pmol/l Range 12-22
These results show that you are undermedicated and need an increase in your dose of Levo. The aim of a treated Hypo patient on Levo only, generally, is for TSH to be 1 or below with FT4 and FT3 in the upper part of their reference ranges if that is where you feel well. Your TSH is way too high, your FT4 is only 27% through range and your FT3 is 37.84% through range.
You need an increase of 25mcg Levo now, retest in 6-8 weeks, I think further increases are inevitable.
Use the following to support your request for an increase in dose if GP doesn't offer one:
Fine tuning of the dose could be necessary in some patients
* aim of levothyroxine treatment is to make the patient feel better, and the dose should be adjusted to maintain the level of thyroid stimulating hormone within the lower half of the reference range, around 0.4 to 2.5 mU/l. If the patient feels perfectly well with a level in the upper half of the reference range, then adjustment is unnecessary
Replacement therapy with levothyroxine should be initiated in all patients to achieve a TSH level of 0.5-2.0pmol/L.
*
Dr Toft, past president of the British Thyroid Association and leading endocrinologist, states in Pulse Magazine (the professional magazine for doctors):
"The appropriate dose of levothyroxine is that which restores euthyroidism and serum TSH to the lower part of the reference range - 0.2-0.5mU/l. In this case, free thyroxine is likely to be in the upper part of its reference range or even slightly elevated – 18-22pmol/l. Most patients will feel well in that circumstance. But some need a higher dose of levothyroxine to suppress serum TSH and then the serum-free T4 concentration will be elevated at around 24-28pmol/l. This 'exogenous subclinical hyperthyroidism' is not dangerous as long as serum T3 is unequivocally normal – that is, serum total around T3 1.7nmol/l (reference range 1.0-2.2nmol/l).*"
*He recently confirmed, during a public meeting, that this applies to Free T3 as well as Total T3.
You can obtain a copy of the article by emailing Dionne at
tukadmin@thyroiduk.org
print it and highlight question 6 to show your doctor.
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AUTOIMMUNITY.
THYOGLOBULIN ANTIBODIES 760.0 IU/mL ( Range 0-115)
Your raised antibodies confirm autoimmune thyroid disease, known to patients as Hashimoto's. Did you know this?
Hashi's is where the immune system attacks and gradually destroys the thyroid, it's the most common cause of hypothyroidism. When the attacks happen the thyroid releases a load of hormone and the antibodies come along and mop up the mess.
Some Hashi's patients have found a gluten free diet helps but there's no guarantee.
Thanks for the reply, I am taking action re your information , ordered coeliac blood test , eating more Liver, ordered some Vd3 soft gels, speaking with doctor re upping levothyroxine.
The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported
In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned
Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.
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