Normal T3 but T4/TSH abnormal - cause? - Thyroid UK

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Normal T3 but T4/TSH abnormal - cause?

M33R4 profile image
6 Replies

History:

Diagnosed with Hashimoto's since Jan 2019 ; didn't get on with Levothyroxine.

Was taking porcine thyroid from Thailand but supplies stopped over 1 year ago and the current stock they have is overpriced.

Moved onto Metative ii from 12 Aug 2020.

Blood results from 22 Sep 2020 & 16 Apr 2021:

T3= 4.9 pmol/L (Sep 2020 - normal) + 4.4 pmol/L (Apr 2021 - normal)

T4= 12.2 pmol/L (September 2020 - normal) + 10.8 pmol/L (April 2021 - abnormal)

TSH= 0.05 miu/L (Sep 2020 - abnormal) + 0.05 miu/L (Apr 2021 - abnormal)

Current medications/supplements:

Metavive ii - 2 capsules daily (started Aug 2020)

HRT - Estradot and Utrogestan (started July 2020)

Tostran gel (started July 2020)

Multivitamins and minerals

Omega oils

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M33R4
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6 Replies
greygoose profile image
greygoose

Can you give the actual ranges, please. Just saying 'normal' or 'abnormal' is meaningless. I can see your TSH is low, but that's to be expected if taking something that contains T3. Also, when taking T3, your FT4 will be low, because taking T3 lowers T4. But, your FT3 also looks low, so you're probably under-medicated. But, impossible to say for sure without the actual range.

'Normal', when said by a medical person, just means 'in-range'. 'Abnormal' therefore just means below or above range. But neither tell you anything useful about your thyroid status, if you see what I mean. :)

Multi-vitamins are really not recommended on here, for a variety of reasons:

* If your multi contains iron, it will block the absorption of all the vitamins - you won't absorb a single one! Iron should be taken at least two hours away from any other supplement except vit C, which is necessary to aid absorption of iron, and protect the stomach.

* If your multi also contains calcium, the iron and calcium will bind together and you won't be able to absorb either of them.

* Multi's often contain things you shouldn't take or don't need : calcium, iodine, copper. These things should be tested before supplementing.

* Multi's often contain the cheapest, least absorbable form of the supplement : magnesium oxide, instead of magnesium citrate or one of the other good forms; cyanocobalamin instead of methylcobalamin; folic acid instead of methylfolate; etc. etc. etc. This is especially true of supermarket multis.

* Multi's do not contain enough of anything to help a true deficiency, even if you could absorb them.

* When taking several supplements, you should start them individually at two weekly intervals, not all at once as you would with a multi. Because, if you start them all at once, and something doesn't agree with you, you won't know which one it is and you'll be back to square one.

* Most supplements should be taken at least two hours away from thyroid hormone, but some - iron, vit D, magnesium and calcium (should you really need to take it) should be taken at least four hours away from thyroid hormone.

*Vit C should be taken 2 hours away from B12 because it affects how the body uses B12.

*Never take magnesium/zinc/calcium at the same time as they affect the absorption of each other.

*Take zinc and copper separately as zinc affects the absorption of copper.

*Vits A/D/E/K are all fat soluble vitamins, and if taken together can compete for the source of fat. They are best taken away from each other.

* The magnesium you take - and just about everybody needs to take it - should be chosen according to what you want it to do:

Magnesium citrate: mild laxative, best for constipation.

Magnesium taurate: best for cardiovascular health.

Magnesium malate: best for fatigue – helps make ATP energy.

Magnesium glycinate: most bioavailable and absorbable form, non-laxative.

Magnesium chloride: for detoxing the cells and tissues, aids kidney function and can boost a sluggish metabolism.

Magnesium carbonate: good for people suffering with indigestion and acid reflux as it contains antacid properties.

Worst forms of magnesium: oxide, sulphate, glutamate and aspartate.

With a multivitamin, you are just throwing your money down the drain, at best, and doing actual harm at worst. Far better to get tested for vit D, vit B12, folate and ferritin, and build up your supplementation program based on the results. A vitamin or a mineral is only going to help you if you need it, anyway. More of something you don’t need is not better, it's either pointless or even dangerous, as with iodine, calcium, iron or vit D. :)

M33R4 profile image
M33R4 in reply to greygoose

Hi greygoose - many thanks for the effort you've put into your reply. It's much appreciated.

Results attached with the range.

I was in a rush when I posted so my apologies for not being more clear.

I don't take multivitamins but take the following:-

Morning:

Thyroid medication - was Metavive ii

Lunchtime:

Cod liver oil

Vit D 3

Milk thistle

Bedtime:

Ferrous fumarate (for my B-thalassemia trait from birth)

Vit E

Tostran gel - one pea size amount every other day or 3 alternate days a week)

Estradot patch - Tue and Sat

Utrogestan - take for 7 days towards the end of the month to induce menstruation

I don't currently take magnesium but will add this to my bedtime routine.

My B12 was tested in 2019 and the result out of the 37.5 - 188 range was 49.800 pmol/L.

I will also add bitter gourd tablets for my blood sugar (I am not diabetic but ensuring blood sugar is a good thing for someone like me who has a sweet tooth).

Thyroid test results - page 2
M33R4 profile image
M33R4 in reply to M33R4

Continuing thyroid results

Thyroid results - page 1
greygoose profile image
greygoose in reply to M33R4

Sorry for the tirade on multi-vits, but you did say in your original post, that you took them.

So, let's have a look at what you do take.

Lunchtime:

Cod liver oil

Vit D 3

Milk thistle

If you're taking vit D, you also need to take vit K2-MK7. Taking vit d increases the absorption of calcium from food, and the K2 makes sure it gets into the bones and teeth, and doesn't build up in the soft tissues.

Bedtime:

Ferrous fumarate (for my B-thalassemia trait from birth)

Vit E

Tostran gel - one pea size amount every other day or 3 alternate days a week)

Estradot patch - Tue and Sat

Utrogestan - take for 7 days towards the end of the month to induce menstruation

I don't currently take magnesium but will add this to my bedtime routine.

I'm afraid that's just not going to work. Iron has to be taken at least two hours away from everything, except vit C. And, you need the vit C to help with absorption and avoid constipation.

Magnesium shouldn't be taken with any other mineral,

My B12 was tested in 2019 and the result out of the 37.5 - 188 range was 49.800 pmol/L.

If my B12 was that low, I would want testing for Pernicious Anemia. And, it could be lower now. But, get it retested first.

The problem with Metavive is that we can have no idea how much hormone is in it. But, you are obviously under-medicated. Looks like you were having some Hashi's 'hyper' swings in 2019/20, but since August 2020, the trend has been down, and your FT3 never goes over 50% of the range, which is too low. I would say, you need to try increasing your dose.

No point in retesting antibodies, it doesn't give you any extra information. Once you have had them over-range, you have the proof of Hashi's, and that doesn't go away, no matter what the antibodies do. :)

M33R4 profile image
M33R4 in reply to greygoose

Re: NOT taking magnesium with other minerals - do zinc and magnesium not work/complement one another?

greygoose profile image
greygoose in reply to M33R4

No, I know you're not taking magnesium, but you said you were thinking about taking it at bedtime. My point was, iron should not be taken with anything else.

Lots of things complement each other, but that doesn't mean it's a good idea to take them together. They can affect the absorption, one of the other.

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