CBD oil and Levothyroxine

[Molly139]

I’ve received my first order of Jacob Hooy 2.75% from Holland & Barrett. I want to try it to help with anxiety and just realised I haven’t checked if it’s safe to take with levothyroxine. I can’t ask my GP as they’re closed today. Could anyone advise please

[SlowDragon Administrator]

Anxiety is common hypothyroid symptom

How much levothyroxine are you currently taking

Do you always get same brand levothyroxine at each prescription

What vitamin supplements are you currently taking

When were thyroid and vitamin levels last tested

[Molly139 in reply to SlowDragon]

100mcg of levothyroxine tested 3 months ago bloods took before food. I’m supplementing with vit D, K2 and magnesium.

[SlowDragon Administrator in reply to Molly139]

Do you have the actual results and ranges ?

When were B12, folate and ferritin last tested

[Molly139 in reply to SlowDragon]

July 2020 Thriva resultsB12 139 (37.5-188)

TSH 0.03 (0.27-4.3)

Free T3 4.4 (3.1-6.8)

FT4 26.3 (12-22)

Thyroglobulin antibodies 958.9 (0-115)

Thyroid peroxidose anti 60 (0-34)

Total thyroxine (T4) 154 (59-154)

25 OH Vit D 43 (75-175)

Ferritin 194 (13-150)

Folate 15.2 (8.83-60.8)

November 2020 GP results

TSH 2.8 (0.27-4.3)

Cortisol 412 nmol/L (equal of greater than 350)

Vitamin D 73

[SlowDragon Administrator in reply to Molly139]

So in July your Ft4 was high and Ft3 low

So poor conversion of Ft4 to ft3

Presumably you knew you have autoimmune thyroid disease also called Hashimoto’s diagnosed by high thyroid antibodies

Poor conversion of Ft4 to ft3 is common with autoimmune thyroid disease (Hashimoto’s)

Getting all four vitamins optimal can help improve conversion

Vitamin D was too low can see in November this was much better at 73

Aiming to improve to at least around 80nmol and around 100nmol maybe better

Folate was low

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid) may be beneficial. This can help keep all B vitamins in balance

Difference between folate and folic acid

chriskresser.com/folate-vs-...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Igennus Super B is good quality and cheap vitamin B complex. Contains folate. Full dose is two tablets per day. Many/most people may only need one tablet per day. Certainly only start on one per day (or even half tablet per day for first couple of weeks)

Or Thorne Basic B is another option that contain folate, but is large capsule

IMPORTANT. If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

Have you had coeliac blood test done

Are you now on absolutely strictly gluten free diet

[Molly139 in reply to SlowDragon]

So, if I get my vitamins optimal this will Improve conversion which will improve the anxiety, is that correct? I would prefer to follow this route rather than CBD, which to be honest makes me a bit anxious.

Coeliac test was negative. Regarding gluten free I avoid it but confess to having a little now and again like today I had a hash brown!

[SlowDragon Administrator in reply to Molly139]

Gluten free diet has to be absolutely strictly gluten free to be effective

It takes 4-6 months for gut to recover each time you eat gluten

If TSH is over 2 you likely need further increase in levothyroxine

[SlowDragon Administrator in reply to Molly139]

November 2020 GP results

TSH 2.8 (0.27-4.3)

This suggests now under medicated

You need to get TSH, Ft4 and Ft3 tested together

All thyroid tests should be done as early as possible in morning before eating or drinking anything other than water and last dose levothyroxine 24 hours before test

cheapest option for just TSH, FT4 and FT3

£29 (via NHS private service ) and 10% off down to £26.10 if go on thyroid uk for code

thyroiduk.org/getting-a-dia...

monitormyhealth.org.uk/

[Molly139 in reply to SlowDragon]

Will getting my results optimal improve anxiety? If it will I’ll book a full thyroid and vitamin test tomorrow

[SlowDragon Administrator in reply to Molly139]

Yes

Anxiety is very common when inadequately treated

[Molly139 in reply to SlowDragon]

Thank you so much, you’ve been brilliant. I’ll post my results when I get them and will be returning the CBD!

[SlowDragon Administrator in reply to Molly139]

TSH should be under 2 as an absolute maximum when on levothyroxine

gponline.com/endocrinology-...

Replacement therapy with levothyroxine should be initiated in all patients to achieve a TSH level of 0.5-2.0pmol/L.

NHS England Liothyronine guidelines July 2019 clearly state on page 13 that TSH should be between 0.4-1.5 when OPTIMALLY treated with just Levothyroxine

Note that it says test should be in morning BEFORE taking levothyroxine

Also to test vitamin D, folate, B12 and ferritin

sps.nhs.uk/wp-content/uploa...

Aim is to bring a TSH under 2.5

UK guidance suggests aiming for a TSH of 0.5–2.5

gp-update.co.uk/SM4/Mutable...

Dr Toft, past president of the British Thyroid Association and leading endocrinologist, states in Pulse Magazine,

"The appropriate dose of levothyroxine is that which restores euthyroidism and serum TSH to the lower part of the reference range - 0.2-0.5mU/l.

In this case, free thyroxine is likely to be in the upper part of its reference range or even slightly elevated – 18-22pmol/l.

Most patients will feel well in that circumstance.

But some need a higher dose of levothyroxine to suppress serum TSH and then the serum-free T4 concentration will be elevated at around 24-28pmol/l.

This 'exogenous subclinical hyperthyroidism' is not dangerous as long as serum T3 is unequivocally normal – that is, serum total around T3 1.7nmol/l (reference range 1.0-2.2nmol/l)."

(That’s Ft3 at 58% minimum through range)

You can obtain a copy of the articles from Thyroid UK email print it and highlight question 6 to show your doctor



please email Dionne at

[e-mail]

[Molly139 in reply to SlowDragon]

I’m currently daily supplementing:Vitamin D 4000 iu

K2 MK7 400ug

Cod liver oil with omega 3 1000mg

Calc Carb 30 1 per day from homeopath