Is consuming soya milk not advised? Under activ... - Thyroid UK

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Is consuming soya milk not advised? Under active thyroid

CharlyMae profile image
15 Replies

Hey,

I am a huge soya fan and drink around 400ml a day, not including other products.

I am dairy free and soya was my go to. It has been for years.

Should I stop drinking it? The doctor hasn’t advise any diet changes but I keep reading about it.

Thanks :)

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CharlyMae profile image
CharlyMae
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15 Replies
greygoose profile image
greygoose

Soy is a very bad thing to consume for everybody - it is not a health food - but especially for hypos. So many things wrong with it, I don't know where to begin. So, I'll start with this post from earlier:

healthunlocked.com/thyroidu...

But, the main problem for hypos is that it impedes the uptake of thyroid hormone by the cells. So, you can have good levels in the blood but will still be hypo because it's not getting into the cells.

I would give it up if I were you.

Buddy195 profile image
Buddy195Administrator

Are you vegan or dairy free CharleyMae? If so, could you swap to almond milk. Some also find benefit with low lactose dairy milk, if traditional dairy milk causes issues/ inflammation.

CharlyMae profile image
CharlyMae in reply toBuddy195

I am allergic to cows milk :)

Karenk13 profile image
Karenk13 in reply toCharlyMae

Same I switch between Oat milk and Soy milk as they both have the best consistencies especially in coffees 😊

SlowDragon profile image
SlowDragonAdministrator

If you stop drinking soya milk, get thyroid levels retested 6-8 weeks later. You may need to adjust your dose levothyroxine

dipsyqueen profile image
dipsyqueen in reply toSlowDragon

Does this include edamame as this seems to be quite common in a mixed veg pack thanks

SlowDragon profile image
SlowDragonAdministrator in reply todipsyqueen

Depends how often you are eating them....once or twice month probably not an issue

Once a day might be

I tend to avoid all soya

Hashihouseman profile image
Hashihouseman

Take an experts view perhaps.....

markvanderpump.co.uk/blog/p...

There may be good reasons to eat soya products and like any potential foodstuff there are pros and cons depending on individual affinities or sensitivities and the way the foodstuff is produced and processed. But it is a food and there is no evidence it causes hypothyroidism, if there was entire Asian nations would see epidemics of soy related thyroid issues.

Yet another myth..... where’s the evidence for it interfering with cellular membrane thyroid transporters?!?

helvella profile image
helvellaAdministrator in reply toHashihouseman

There is at least some here:

Arch Toxicol. 2018; 92(9): 2703–2748.

Published online 2018 Aug 21. doi: 10.1007/s00204-018-2279-8

PMCID: PMC6132702

PMID: 30132047

Effects of isoflavones on breast tissue and the thyroid hormone system in humans: a comprehensive safety evaluation

Isoflavones may interact with various different components of the thyroid hormone cascade (Fig. 5). In vitro studies have shown that soy isoflavones themselves can act as a substrate for TPO, i.e., they can be iodinated and, therefore, can act as competitive substrates (Divi et al. 1997). This hypothesis is supported by a human study reporting the detection of iodinated isoflavones in human urine after supplementation with isoflavonoids (see “Isoflavone metabolism and concentrations in plasma and target tissues metabolism”; Sosvorova et al. 2012). Furthermore, in the case of an iodine deficiency, direct inhibition of the enzyme by covalent binding of isoflavones has been reported (Fig. 5, A). The half-maximum inhibition (IC50) of TPO of porcine origin is already reached at a genistein and daidzein concentration of approx. 1–10 µM (Divi et al. 1997). Furthermore, genistein but not daidzein was reported to act as a potent inhibitor of human DIO1 (hDIO1) in vitro (Fig. 5, B), while no effect was observed in the case of hDIO2 and hDIO3 (Renko et al. 2015). Another target of isoflavones might be TTR. Genistein and related (iso)flavones are highly effective in inhibiting the binding of TTR to T4 and T3 (KD = 40 nM, equimolar to T4 binding) in serum and CSF (Fig. 5, C). Thus, they may alter the kinetics and distribution of thyroid hormones in the body (Green et al. 2005; Radovic et al. 2006). At the present time it is being discussed whether isoflavones may also influence the transmembrane transport of thyroid hormones by specifically interacting with individual TTHTs such as MCT8, MCT10, LAT1, LAT2 or OATP1C1 (Fig. 5, D; Braun and Schweizer 2015; Johannes et al. 2016; Kinne et al. 2010). Genistein may even act as a powerful chaperone activator of mutated MCT8 in the Allan–Herndon–Dudley syndrome by rescuing expression of the mutated TTHT and favouring its functional expression in the plasma membrane (Braun and Schweizer 2017). Isoflavones may also impact thyroid hormone metabolism, e.g., by inhibiting sulfotransferases (Fig. 5, E; Ebmeier and Anderson 2004).

Hüser S, Guth S, Joost HG, et al. Effects of isoflavones on breast tissue and the thyroid hormone system in humans: a comprehensive safety evaluation. Arch Toxicol. 2018;92(9):2703-2748. doi:10.1007/s00204-018-2279-8

Hashihouseman profile image
Hashihouseman in reply tohelvella

Thanks for that, it all seems inconclusive and perhaps more a concern if you have subclinical hypothyroidism and are therefore at risk of needing replacement later or are female. pending any better evidence it seems that it you are male and already on replacement therapy soya compounds are of minimal risk and of some benefit.

in reply toHashihouseman

Soy in the southern Hemisphere is totally different to western!

There's is a natural Fermented Soya that removes any badness

While Western Soya is GMO non Fermented cheap stuff treated with Glyphosates etc so loaded with Phytoestrogens that radicalise in the body creating cancer cells.

We can tolerate wheat while Asian Cultures can't they have soy and Rice.

helvella profile image
helvellaAdministrator in reply to

I believe that is not quite the case. For example, soy milk (bought or homemade) apparently is widely consumed in China. One tiny article:

chinasichuanfood.com/how-to...

in reply tohelvella

As i said Asia Soy isn't the same as Western world stuff that is grown Chemically induced with GMO seeds.

Asia has had soya as a staple food for "Years" but not wheat which there bodies can't deal with very well one reason so many struggle with likes of Beer.

Where as were other way round as always had wheat but not Soya.

Soy grown in USA/UK is GMO and "Non" fermented which takes out the nasties like they do in Asia.

Last time i looked China was in southern Hemisphere/Asia!

Got to learn about a lot of this stuff when i did my Sports Coaching Deg's with nutrition

helvella profile image
helvellaAdministrator in reply to

China imports vast quantities of soy - from USA and Brazil - among others.

reuters.com/article/us-chin...

(I think it has now hit 100 million tonnes.)

China is in the northern hemisphere.

World map showing equator
Hashihouseman profile image
Hashihouseman in reply to

I only consume organic/so no glyphosate, and phytoestrogens are good for me! In fact it because of the effect of thyroid replacement on sex hormone binding globulin I need soy! They's also associated with an immune protective effect against covid!

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