Was I seeing things or did I read that there’s more than one type of T3 that the body makes

[Noelnoel]

If so, can you please post the link

Thank you

[Lalatoot]

There are different manufacturers of T3if that is what you mean.

T3 in tablet form is liothyronine. T3 is also contained in NDT (natural dessicated thyroid)

Then there are different measures of t3 - total T3, FT3 (free t3) and RT3 (reverse T3)

[Noelnoel in reply to Lalatoot]

Thank you Lalatoot. I edited the question because what I actually meant was: the different types of T3 the body makes. I read it on here I think but it could’ve been somewhere else I suppose

[helvella Administrator]

noelnoel,

I am not 100% sure what you mean by that question. But I'll take a guess and hope - if I am wrong, let me know.

Almost all T3 as medicine, often called liothyronine, is in the form of the sodium salt of triiodothyronine - liothyronine sodium.

pubchem.ncbi.nlm.nih.gov/co...

One make of liothyronine is in the form of the hydrochloride of triiodothyronine - liothyronine hydrochloride. This is Thybon Henning.

pubchem.ncbi.nlm.nih.gov/co...

There is almost nothing I have ever found which suggests any real-world difference between the two forms. A few people have reported that they feel different on Thybon Henning than on other makes. Trouble is, it is very hard to pin that change in feeling on this very small chemical difference rather than, for example, the other ingredients.

The absolute amounts of sodium and hydrochloride are truly tiny and absolutely dwarfed by the quantities in our diets (even a very low salt / low sodium diet).

[Noelnoel]

Thank you hellvella, I edited the question because what I actually meant was: the different types of T3 the body makes. I read it on here I think but it could’ve been somewhere else I suppose

[DippyDame in reply to Noelnoel]

The body only makes one form of T3 which is called triiodothyronine.

The T3 that is manufactured and taken exogenously is called liothyronine

Liothyronine is available in different strengths, and is available with different brand names - Tiromel, Cynomel etc

This might help -

yourhormones.info/hormones/...

[Noelnoel in reply to DippyDame]

Thank you DippyDame, I’ll read it when less bogged down with facts and counter facts. According to the naturopath there is more than one type of T3 the body produces. I’ve emailed him and hopefully he’ll explain it to me in the simplest of terms

[tattybogle]

i don't think so.

I think naturally produced T3... is T3, no different forms.

I have read here about there being different sorts of TSH. or at least different strength's of TSH (kind of !) produced at different times of day ?

And i have read about T3 having a different 'half life' in hyperthyroidism / hypothyroidism and euthyroidism. (it lasts longer in the body in hypo , and shorter in hyper)

But i'm pretty sure i've never read anything here about actual different sorts of natural T3.

Unless you mean rT3 ? (reverse T3) which is like T3 but made the opposite way round so it doesn't fit on the receptors and therefore can't activate them (sort of- forgive the unscientific explanation)

[Noelnoel in reply to tattybogle]

Thank you tattyboogle. I definitely saw somewhere that the body makes different types of T3. I wish now that I’d paid more attention but at the time I just didn’t have the headspace to take it on

[tattybogle in reply to Noelnoel]

i've got a bad habit of bookmarking interesting things 'for later' but not labelling them , so now i've got about 150 bookmarked science papers that i've no idea what snippet of information i saved them for.

doh !

If i DO ever come across something about different sorts of T3. i'll remember someone asked .......

but i won't remember who

[Noelnoel in reply to tattybogle]

Hilarious!

[Noelnoel in reply to tattybogle]

I do that sort of thing ALL the time

[helvella Administrator in reply to tattybogle]

Do you happen to use Microsoft Office? Do you have OneNote?

An extremely useful tool for storing snippets. And, if you copy even a word from a webpage, it adds the link it came from. Pictures. Text. Tables.

[tattybogle in reply to helvella]

I really don't know how to respond to that , other than to say

UG.. ME PUSH POINTY ARROW WITH UM FINGR... MAGIC BOX SHOW ME PRETTY PICTURE... UG!

(you have no idea how impressed my kids are that i can copy and paste now , i don't even know if i 'have' Microsoft anything, and if you asked me to find their Office , i'd maybe go and look in the phone book....)

[Noelnoel in reply to helvella]

Thank you hellvella. What tattyboogle says below could easily be me but those tools you mention sound extremely handy. I’ll investigate

[tattybogle in reply to tattybogle]

Some bit's of this might interest you Noelnoel ,

thyroidpatients.ca/2019/11/...

[humanbean]

Are you thinking of Reverse T3?

When there is an excess of T4 in the body it gets converted to Reverse T3. This doesn't have any active effect in the body and is quickly converted to T2 then T1 and then is excreted.

[Noelnoel in reply to humanbean]

possibly, humanbean. Thoroughly confused right now but hopefully, I’ll know more later today

[greygoose]

Are you thinking about jimh111 's references to the different deiodinases that convert T4 to T3 under different circumstances? Perhaps he'll pop along and explain that - because I can't! lol

[Noelnoel in reply to greygoose]

Thank you gg, I’m beginning to doubt what I saw. I might’ve forgotten all about it had the naturopath I spoke today, not mentioned the types of T3 found in the body. I then said to him, funny you should say that because I read about it somewhere. He then asked me to find the source and send him the link because I think it’s either a fairly new discovery or not much talked about. I’ve emailed him to ask for more info because it was just a comment made in passing and I didn’t revisit it

Again, it was because I can barely understand the workings of one T3, never mind several

Not sure if I can mention his name here

[greygoose in reply to Noelnoel]

Oh, I think he must mean Free T3, bound T3 and rT3. I've never heard of any other type of T3.

[Noelnoel in reply to greygoose]

gg, it’s entirely possible. Hopefully, I’ll find out today

[helvella Administrator in reply to Noelnoel]

Feel free to let me know by Private Message.

[juma34]

There are indeed two types of T3 the body makes. The first form is 3,5,3'-Triiodothyronine (short name: T3) - it's the the metabolic active form of T3. en.wikipedia.org/wiki/Triio...

The second form is 3,3’,5’-triiodothyronine (short name: rT3 or reverse T3). It's a isomer of T3 and is the metabolic inactive form of T3.

en.wikipedia.org/wiki/Rever...