Liquid thyroxine allergy!: Sorry long story... - Thyroid UK

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Liquid thyroxine allergy!

MrsHashimot profile image

Sorry long story, please help!

I have been on thyroxine for the past 20 years, but for the last 18 months I have suffered from severe allergic reactions and finally worked out I am allergic to additives in all tablets amongst other things. Finally convinced my doctor to try me on liquid thyroxine. My pharmacy ordered me two bottles, the first being Ten Pharma brand and the second to collect at a later date. The Ten Pharma brand was brilliant and I had no adverse reaction. When I went to pick up the second bottle it was Teva brand, which I wasn’t happy about as Ten Pharma was fine. As soon as I started taking the teva brand I had a severe reaction. The pharmacist is now telling me he is having trouble getting Ten Pharma brand. I haven’t taken any thyroxine for a week now!

Am at my Wits End! Any suggestions, advice, help would be much appreciated x

21 Replies
SeasideSusie profile image


The first thing I would do is contact the makers of Ten Pharma to see if there is any supply problem. If not then maybe ring round other pharmacies to find one who can source it for you.

Email address for Ten Pharma taken from ThyroidUK's main website:

Check out Ten Pharma details on ThyroidUK's main website here:

Scroll down for liquid Levo. You can check out ingredients of all brands to see if there is another one that is identical or near to Ten Pharma.

Thank you! I have tried to do both the things you have suggested! I can’t find a telephone number for ten pharma and it comes up with a supplier called Jenson pharmaceuticals and when I look them up the company has dissolved!😡🤦‍♀️

helvella profile image
helvellaAdministrator in reply to MrsHashimot

Details for almost every company are available on the EMC site:

Ten Pharma (a subsidiary of BCM Specials Ltd)


1, Thane Road West, NG2 3AA


+44 (0)115 968 6464

Medical Information Direct Line

+44 (0)1271 334 609

Customer Care direct line

+44 (0)1271 334 609



+44 (0) 115 959 1098

Medical Information e-mail

MrsHashimot profile image
MrsHashimot in reply to helvella

Thank you sooooo much! I have just spoken to some at Ten Pharma and they are going to ring me back. I’ll let you know what they say x

helvella profile image
helvellaAdministrator in reply to MrsHashimot

Please do! 😀

SlowDragon profile image

As you have Hashimoto’s do you regularly get vitamin D, folate, ferritin and B12 tested?

Gut malabsorption and food intolerances can cause low vitamin levels

Are you on strictly gluten free diet or dairy free diet

I am hypothyroid. I have been doing an elimination diet because of the allergies. I have cut out gluten and lactose

SlowDragon profile image
SlowDragonAdministrator in reply to MrsHashimot

I realise you’re hypothyroid, you have Hashimoto’s

When were vitamin levels last tested

What vitamin supplements are you currently taking

No vitamins being taken as they are usually in tablets and contain the things I am allergic to! What would you recommend please x

SlowDragon profile image
SlowDragonAdministrator in reply to MrsHashimot

Getting tested first ....ALWAYS

Only test thyroid levels after 6-8 weeks on constant unchanging dose and brand of levothyroxine

For full Thyroid evaluation you need TSH, FT4 and FT3 tested. Also EXTREMELY important to test vitamin D, folate, ferritin and B12

Low vitamin levels are extremely common with Hashimoto’s

Ask GP to test vitamin levels NOW

Or test vitamins at next thyroid test

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water .

Last dose of Levothyroxine 24 hours prior to blood test. (taking delayed dose immediately after blood draw).

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Private tests are available as NHS currently rarely tests Ft3 or thyroid antibodies or all relevant vitamins

List of private testing options

Medichecks Thyroid plus antibodies and vitamins

Thriva Thyroid plus antibodies and vitamins By DIY fingerpick test

Thriva also offer just vitamin testing

Blue Horizon Thyroid Premium Gold includes antibodies, cortisol and vitamins by DIY fingerprick test

If you can get GP to test vitamins then cheapest option for just TSH, FT4 and FT3

£29 (via NHS private service ) and 10% off down to £26.10 if go on thyroid uk for code

As for being tested, no. Supposed to go for allergy testing but because of pandemic the appointment was cancelled

SlowDragon profile image
SlowDragonAdministrator in reply to MrsHashimot

High percentage of Hashimoto’s patients develop gluten intolerance, at least over 80%

Lactose intolerance also almost as common

Sometimes lactose intolerance improves after year or two strictly gluten free

Do you know whats in the Teva liquid compared to the Ten one?

SeasideSusie profile image
SeasideSusieAdministrator in reply to MichelleHarris

The second link I gave in my reply above goes to a document which lists all ingredients of all levothyroxine including liquid forms

Thyb profile image
Thyb in reply to MichelleHarris

MichelleHarris Please see my reply below 'underneath SeasideSusie's. Very little difference x

The only difference I can see between Ten Pharma and Teva liquid levothyroxine:-

Teva contains sodium hydroxide- Ten Pharma doesn't

Ten Pharma contains E217, Teva doesn't

Teva contains anhydrous levothyroxine sodium

Ten pharma contains levothyroxine sodium

Is there a difference between 'anhydrous levothyroxine sodium' and levothyroxine sodium?? helvella SeasideSusie

MrsHashimot could you tell me what reaction you had to the Teva liquid levothyroxine please?? MrsHashimot

SeasideSusie profile image
SeasideSusieAdministrator in reply to Thyb


Is there a difference between 'anhydrous levothyroxine sodium' and levothyroxine sodium?? helvella SeasideSusie

Anhydrous just means "without water".

helvella gave an excellent explanation of this this a few years ago which I think reading the whole thread will help:

helvella profile image
helvellaAdministrator in reply to SeasideSusie

I also produced a specific document on this question!

Once it is in a water-based liquid (as oral solutions obviously are!), it will not be anhydrous any longer!

No Rhyme or reason!? I have had allergic reactions to lots of tablets over time. Thought I was allergic to caking agents, preservatives in tablets. Until have allergy tests, will not know definitively. It’s just a matter of trial and error, which is very frustrating and painful! The symptoms start with itching streaming eyes. Red, swollen, itchy hands, ears and chest and then hives. Throat gets tingerly and scratchy and sometimes breathless and dizzy. Not much fun!😩. Will let you know whether I get my medication today. Day 9 without thyroxine!!

helvella profile image
helvellaAdministrator in reply to MrsHashimot

Afraid you have replied to yourself!

I think you meant to respond to Thyb

helvella profile image


I hope you will, or already have, filed Yellow Card reports for all the products you have suffered from.

In the end, it is ONLY feedback from patients which will identify issues. An individual report by an individual patient will do little on its own. But as reports accumulate, they most certainly help. And even a single report means they (whether the MHRA or a pharmaceutical company) can no longer say "We've had no reports about xxxxx"!

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