Looking for further reading/research on low TSH

[Lilacsocks]

Hello again,

Firstly, thanks for all the info so far!

I have previously posted my results and thyroid background in another thread. I take thyroxine following RAI

I was wondering if anyone knew of further reading/information/research on low but not suppressed TSH (I'm at 0.08), specifically in pregnancy and the safety of this. Or some good websites I might get more info.

Thanks again.

[diogenes Remembering]

I believe this paper is on TUK files.

Thyroid 2017 Apr;27(4):484-490. doi: 10.1089/thy.2016.0426. Epub 2017 Feb 6.

Biochemical Markers Reflecting Thyroid Function in Athyreotic Patients on Levothyroxine Monotherapy

Mitsuru Ito 1 , Akira Miyauchi 1 , Mako Hisakado 1 , Waka Yoshioka 1 , Akane Ide 1 , Takumi Kudo 1 , Eijun Nishihara 1 , Minoru Kihara 1 , Yasuhiro Ito 1 , Kaoru Kobayashi 1 , Akihiro Miya 1 , Shuji Fukata 1 , Mitsushige Nishikawa 1 , Hirotoshi Nakamura 1 , Nobuyuki Amino 1

PMID: 28056660 PMCID: PMC5385443 DOI: 10.1089/thy.2016.0426

[jimh111 in reply to diogenes]

Available for free here researchgate.net/publicatio... .

[Lilacsocks in reply to jimh111]

Thank you 😊

[radd]

Lilacsocks,

If you are medicating thyroid hormone replacement you will need a low TSH whilst pregnant. This not ensures you are medicating adequate thyroid hormone but helps regulate other hormones that fluctuate during pregnancy.

During the first trimester not only will your baby depend on your supply of thyroid hormone (as does not have his own supply until later) but your oestrogen levels will raise, encouraging TBG (thyroid binding globulin) to correspondingly raise and this binds to thyroid hormones, disabling a proportion.

A good read is "Your Healthy Pregnancy With Thyroid Disease" by Dana Trentini and Mary Shomon.

A good website is hypothyroidmom.com/hypothyr...

Also NICE guidelines cks.nice.org.uk/topics/hypo...