Hi all, since starting levothyroxine I've had mental slowing which has been so disabling. I have also had chronic and continuous constipation. I'm thinking that my problems with digestion, insufficient absorption of levothyroxine resulting in low T3 could be linked to the actions of low serotonin. Serotonin has also been identified to alter mood.
My TSH does not indicate whether or not my thyroid levels are optimum for me. My TSH is 0.02 and I am currently desperate for an increase in levothyroxine as my FT4 is too low for me.
I am not a quack but has your TSH been suppressed by something which is not resulting in good thyroid health, then maybe you should look elsewhere. Like your other chemical messengers, too much dopamine can suppress TSH yet not increases your thyroid hormone,
No my TSH is suppressed because the feedback loop no longer works properly. To be well I need my FT4 and FT3 in the top third of their ranges. My thyroid hormones respond well to levo and lio and they increase. I am just not yet on enough levo. Because I was ill for so long after being hyperthyroid my endo said it would take at least a year for me to find my levels.
I hope your body can tolerate the desired amount of levo for your test levels to reach their desired location, upper top of range, i also hope that the desired quantity of levo does not exceed the maximum dose for your weight. I also hope you do not become thyroid toxicosis on your way or mentally unstable and requiring antipsychotics which may cause you to twitch, get fat and dribble, Good luck.
Im sorry i dont know your thyroid journey, but i would like too. Tell me your journey and please include your reactions to antipsychotics and doses of thyroid meds along the way. xx
Have you had a full thyroid test done....or just TSH and perhaps FT4?
Medics knowledge of thyroid disease is lamentable poor!
Do you have any thyroid labs that you can post....including ref ranges.
TSH, FT4, FT3, Folate, Ferritin,Vit D vit B12 and antibodies... all essential
Difficult to comment without them.
What makes you think you may not be absorbing Levo?
Do test results suggest that?
You need to find out if your conversion of T4 the storage hormone, to T3 the active hormone is adequate.....usually identified by high FT4 with low FT3
You need to optimise vit D, vit B12, folate and ferritin for healthy thyroid function
Your query about T3 being low....is that based on labs?
I'm afraid without full labs members cannot analyse your results. Personally I wouldn't choose serotonin as a way forward. It sounds as if you need replacement thyroid hormones......not "happy" hormones!
What would you recomend, increased dose? i was already on max dose for body weight with symptoms related to graves and over medicated. The issue was none of the other chemical messengers were checked or balanced with the high levels of levothyroxine which caused me serious mental health issues, and not only me but hundreds of people on this forum every day. Seotonin is required for the wave of contrations which moves food along the digestive tract, minw was not moving which increased the likelihood that the food lay rotting in my stomach which caused even more issues with toxicosis, hence why im sick.
Taking an SSRI which modern happy pills are reduce the effectiveness of levo because they alter the way the gut works. I was on citalopram for 5 years.
Sure if they affect levo levo effects the natural version. What goes up must come down. Doesnt it workvia active transport via the Atp, so no concentration gradients are met which could result in a massive imbalance. And I'm feeling it.
No ssris alter the way the receptors in the gut work. This alteration in gut function affects the absorption of levo. This means that folks taking ssris may need a higher dose of levo.
Serotonin causes the contractions along your digestive tract which moves your food along to be excreted if you don't have none or very little your digestive tract will be slow and you may become toxic as you can not rid waste products.
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