T3 Liothyronine that doesn't contain sodium?

[MoJo4004]

Hi,

I am wondering if anyone knows of T3 that doesn't contain sodium chloride?

I have been suffering with water retention since starting on Tiromel and wondered if I'm sensitive to the fillers/sodium.

T3 definitely helps me and I don't want to stop, but would like to find one that doesn't cause this if possible...

[jimh111]

Tiromel like most synthetic T3 is liothyronine sodium. As far as I know it doesn't contain sodium chloride. Since a tablet weighs 20 microgrammes the sodium content will be a lot less (I'm not going to try to add up the weights of each atom in T3!). So, maybe there is two or three millionths of a gramme of sodium in each tablet which suggests your water retention is not due to the sodium content.

Thybon 20 Henning is liothyronine chloride but is only available on prescription.

[helvella Administrator Thyroid UK in reply to jimh111]

Although this is taken from details for a levothyroxine product, rather than liothyronine, the fundamental statement is applicable to both even if the number is slightly different.

2. Qualitative and quantitative composition

Each Levothyroxine Aristo 100 micrograms tablet contains 100 micrograms levothyroxine sodium anhydrous.

Excipient(s) with known effect

This medicinal product contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially 'sodium-free'.

medicines.org.uk/emc/produc...

Remember that the NHS says:

11 years and over – 6g salt a day (2.4g sodium)

nhs.uk/live-well/eat-well/s...

That is more than a hundred times the amount in one of these tablets.

I suggest you look elsewhere than the sodium content of the tablet itself.

[jimh111 in reply to helvella]

This is the figure for Aristo Levothyroxine which contains 'sodium starch glycolate type A' as an excipient. In any event it is a tiny amount as you point out.

Tiromel lists its excipients as: -

Lactose

Polyvinylpyrrolidone

Starch

Magnesium Stereat

I'm guessing none of these are high in sodium.

Water retention may be nothing to do with sodium levels, possibly Tiromel is correcting some metabolic mechanisms or other hormone levels, or it may be a temporary phenomenon.

[helvella Administrator Thyroid UK in reply to jimh111]

Absolutely agree.

Possibly the Tiromel is simply at too low a dose?