AstraZeneca announced it's testing the SGLT-2 inhibitor dapagliflozin (Farxiga) as a possible COVID-19 treatment in the phase III DARE-19 trial. (Reuters)
New research from Glytec suggests that in-hospital mortality is more than quadrupled in COVID-19 patients with diabetes and hyperglycemia.
People could change their diet to reduce the amount of carbs and sugar they eat, increase their healthy fats and protein they eat, reduce their intake of processed foods, and start eating real food, thus reducing the amount of insulin they need. Risk of death from coronavirus can be reduced in just a few weeks.
The current UK medical guidelines for treating people living with diabetes (T1 and T2) are here, in The Lancet: thelancet.com/journals/land...
It appears the study you mention is being carried out in the US, whereas, you will see some way into the body of the document above, in UK hospitals, patients utilising SGLT2 medication (Farxiga is in this class, as well as the 'Flozins) have these medications stopped, due to an increased chance of diabetic ketoacidosis, which can, in itself, be life threatening.
As I understand it, there no current proposal that individuals currently prescribed this medication who are at home, and well, should be discontinuing their medication. Anyone concerned about this should have a conversation with the GP, nurse, or Clinic for any personal guidance.
My take is anyone living with diabetes should be trying their hardest to maintain the best control they can at this time, by whatever means suits them best. I know that isn't necessarily easy for a million reasons.
Contracting COVID-19 appears to increase insulin resistance, therefore making control trickier.
The medics are feeling their way forward in all of this.
Please don't panic. That absolutely is not what I am saying.
What the guidance states is that those being admitted to hospital with COVID-19, who are already taking that class of medication would have that specific medication stopped, whilst in hospital, because in certain circumstances, a small number of people in those circumstances would be likely to develop diabetic ketoacidosis.
In all likelihood, persons having that medication stopped would be given another class of medication. What that would be would depend on the individual and their specific needs.
For an extremely high percentage of individuals, such a step would be purely precautionary, and if that individual carried on with their Flozins, they would be absolutely fine, but for the remaining extremely small percentage it is a step that could save their lives, at worst.
This just one example of why, when we go to hospital it is important the medics know about anything we take - prescription, or otherwise.
Until told otherwise, people living with diabetes should continue to manage it in their usual way, to the best of their abilities, and f course anyone with concerns for their own well-being should contact their GP or NHS 111.
That's not reassuring. What if this medication IS life-saving as far as COVID-19 is concerned? Thery are taking it away for fear the patient MIGHT get ketoacidosis. Unless they have data showing a higher incidence among COVID-19 patients taking the medication, it doesn't seem like a logical move to me.
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