We know that the doctors most of us see are very sophisticated about using drugs to control disease but our condition needs more than that. We have to see where our genetic weaknesses have contributed and what we can do about it. Dr. Kalish has been on many of the functional summits and like most functional doctors wants to find the root cause.
I had friends who have had these lab tests done and analyzed by these professionals. I certainly did not understand them but I'm sure they are close to being the new diagnostic tests that will bring us some amazing information about our bodies.
You only need to view the first five minutes to see what I am talking about.
This is exactly what Dr Ben Lynch who is an expert on epigenetics talks about. He focuses on genetic SNPs and nutrition. Many of our health issues can be resolved by changing the expression of our genes and not dirtying our genes. We are in charge of this. Regardless of whether we have SNPs or not. His expertise is MTHFR.
I’ve yet to read his book Dirty Genes but I love his Facebook posts and his supplements.
Thanks for posting I’ll check out the rest of this video.
Hi Heloise and thanks as always. Really interesting. I know that the genetic information that I have had done has been eye-opening, making sense of my own and family symptoms from way back as well as giving me some help on where to go now (and hopefully how to help the next generation not go through all this!) Best wishes
It IS fascinating , isn't it? I heard one doctor state that there were so many type of supplements and if you were taking the wrong type of zinc it will not help you. But with the genetic test they can tell you which type would benefit you so they are now including the test with the rest of the diagnostics if you want them to. When I think of all the trial and error we have been cursed with, this should propel healing to a new level. Here's to your health!!
Hi, mine was pretty basic and I'm not sure I would recommend the company as I had some problems getting the results and they had missed some out (the fairly vital oestrogen section) and communication was awful. I tested with Optimal Health (the Pro Gene) through Micki Rose's site purehealthclinic.co.uk. Just a mouth swab through the post - very easy. I did let Micki know about the issues as I have done other tests with her with no problems and she has always been great, really helpful. It depends a bit what you are looking for. I was trying to check methylation (and there are plenty of options for doing that, both genetic and functional) and this seemed to offer a bit wider test for the money at the time. I'm glad to have done it, but another test than Optimal might be, well...optimal! I did a functional hepatic test (urine) at the same time so I knew that some of the genetic predisposition was actually affecting me, and I'm not just treating the genetic weakness. Micki also did a test report for me to give me some pointers on where to go next. Have a look at her site - you could always ask her for some advice if you can't find what you are looking for. Best wishes
It really depends on whether the SNPs are active in you - MTHFR variants are common and not necessarily a problem, you have to look both functionally and at the bigger picture of you own health (like normal!)
An RNA test would supply more information but we are assuming there is a problem with C677T A1298C MTRR A66G Definite health issues and the report says the rest are not problematic.
Hi - I became very ill when I hit 50 (the menopause I suppose but as I had been on HRT since 33 after a hysterectomy I didn't know exactly when - my whole body was breaking down - but I was unable to take drugs - not realising at the time my liver was being compromised by a slow moving if not nearly non existent metabolism due to thyroid +++ issues. Anyway to cut a long story short - because I had always studied the science of nutrition I used supplements to feed the body each time I got another symptom and got through and kept myself ticking over until I was diagnosed with Lupus/Hughes Syndrome/Hashi's and AI type II. The symptoms I was experiencing were actually deficiencies as the body desperately tried to keep me alive. So a way forward without drugs worked for me.
Just wondered if you have managed to treat the Lupus/Hughes'/Hashi's etc without drugs or can you now tolerate medication if you have to? Best wishes to you
Hi there - well for 7 years I didn't know it ~WAS Lupus - it was awful - I had the good fortune of having private healthcare at that time (no longer) and went to see a consultant who had a different approach and went back through my childhood ailments up to the present time and sent me to a company called Bio Lab in London - bearing in mind it wasn't like it is today where vitamin testing is quite commonplace - it wasn't back in 2000 ! My results came back dangerously low in zinc - magnesium b vitamins etc. - in fact he said I was suffering with malnutrition. Considering I took supplements every day and had a fantastic diet - unbeknown to me the thyroid gland and adrenals were grabbing everything they needed to keep me alive. I used Vitamin E to thin my blood as it was so sticky it was like chewing gum when I touched it. As it was another 13 years before I got diagnosed with Hashi's - I kept myself going in the same way - and then was put on thyroid hormone - another stage it was found I had adrenal issues so now on low dose steroids and DHEA - but apart from that and antibiotics took no other drugs as was unable to and still can't.
Curious if you've done any detoxing. When liver is overwhelmed which is very probable in your case, it can't handle any more chemicals. It seems that treating the liver with support supplements like alpha lipoic acid and silymarin might be a good start. Maybe a colon cleanse first.....
Hi there - tried all that sort of thing - but just gave me rashes etc. - I dont drink so liver issues were nothing to do with that - but tend not to take anything unless I know I am deficient so have regular tests every three months but damned expensive as I have no private healthcare any more.
Oooh, oooh, drinking doesn't have to be involved in fatty liver which is also a hypo problem. You liver has to clear all toxins but can be overwhelmed and it begins to store toxins in fat cells. Especially that roll under the rib cage. Toxins don't just go away, the body has to do the work.
Would you believe I have the added problem of not being able to metabolise choline - and guess what choline does - is the natural 'dissolver' of fat in the liver - so I am more prone to getting NAFLD You could not make it up.
Honestly, I'm not picking on you, post, but this article came up from NaturalHealth365 and I like his articles.
The importance of early screening for nonalcoholic fatty liver disease
Generally, nonalcoholic fatty liver disease is a silent disease that presents no symptoms. Even when cirrhosis develops, there are rarely symptoms until the liver sustains so much damage that a liver transplant is needed.
For this reason, it’s essential to pay attention to other conditions linked to fatty liver disease, such as high blood pressure, insulin resistance, high blood sugar levels, and obesity. If you have any of these components of metabolic syndrome, talk to your doctor about early screening.
The Fatty Liver Foundation advocates for early screening, and new technology offers a quick, economical, and easy method for early screening known as a FibroScreen. While many insurance companies may not pay for the scan unless you’re displaying symptoms, talk to your doctor about the option of early testing if you have metabolic syndrome.
The key to preventing liver failure is early detection (and immediate changes in lifestyle), so addressing this issue early can certainly save your life.
Hi thanks for your concern and advice - but I am lucky in one way that because of my health issues I am monitored by some 3 specialist hospitals and every three months i have blood tests as well - my health issues are those of monitoring as the issues are all body encompassing - I wish they weren't believe me. I cannot even eat blue cheese or take probiotics as my immune system goes on the attack thinking the mould and the bacteria in the probiotic are the enemy. Thanks again though.
OK, post, I understand. I can get a little carried away because this kind of forum often goes against conventional therapeutics and that is because as we have found doesn't work with chronic disease particularly autoimmune. I hope they help you in spite of that.
Hi there - believe me they might take blood tests but it has been me micro managing my illness with supplements and hormones and keeping an eye on their blood tests - as you say the establishment aren't a lot of good and I agree.
My son had a terrible food poisoning in a foreign country and was bloated for months. He did a 3 step cleanse by Dr. Natura which helped a lot. He's not a perfect eater unfortunately so I told him to try Monolaurin where he broke out in a rash on his bicep. My thought is that the Monolaurin killed bacteria but his body did not clear it out which is always the concern when attempting this. The functional doctors state that if you don't have two BMs a day, you are technically constipated so the least anyone should do to attack this by using cascara or some other assistance.
That's really interesting, thank you. Low zinc ties to high copper which won't help your thyroid and adrenal function although I'm sure you've dealt with that. I found magnesium really helped me and I too am using natural Vit E as a blood thinner although can't get a definite Hughes' diagnosis. Unidentified food intolerances were causing my poor absorption, both gluten and dairy, plus low stomach acid from the AIs. I have COMT and MTHFR variants which seem to make metabolising and detoxifying oestrogen difficult, which explains why contraceptive pill was such a problem - so I didn't risk HRT. My best wishes
I remember looking into them when you mentioned them once before but can't just at the moment remember why I didn't or haven't yet anyway. I'll have another look, thank you x
Gordon Bennet! Auto captions again. If I didn't already know that alpha ketoglutarate existed, what would I make of kitty glitter 8 and Kito Gouda rate?Plus diamond for thiamine - honestly, I wish people would do proper transcripts.
I know, sometimes I try to look them up. But mthfr is pretty lengthy and would be difficult to type out: MTHFR stands for methylenetetrahydrofolate reductase. It's getting attention due to a genetic mutation that may lead to high levels of homocysteine in the blood and low levels of folate and other vitamins.Aug 14, 2019
If you have the defect there are four b vitamins that need to be chosen in methyl formats.
I do usually look them up but I sometimes wonder if they (acronyms) would all come up when Googling. I do agree it would be too time consuming writing that out.
Hi, you really don't want to start supplements based only on genetic information. I don't know which genes you are interested in but a good place to begin with understanding MTHFR and methylation is purehealthclinic.co.uk/heal... and make sure you read the extra articles at the bottom. Whatever the genetic report indicates is only predisposition and if you are lucky may never affect you even if you don't do all the right things. If you know where your potential weaknesses lie you can try to avoid triggers because most of our overall health is down to epigenetics - lifestyle, diet, exercise, stress in all forms (food intolerances etc) as well as other health issues that you may have less control over like viruses and bacterial infections. The body needs balance. The genetic variants interract and it is the whole picture you need to look at. Much better to check functionally how the body's systems are working then address issues holistically, with diet wherever you can. I don't know anything about 23 and me I'm afraid. Once you've had a good read of Micki's site I'm sure you'll have some ideas from your own medical history of where to go next, but she will advise about which test if you are not sure and does offer test reports to help you understand the results. She can refer you to a colleague to help with your 23 and me result. (see the Support page). Hope that helps a bit.
I'm really not qualified to say but I don't think anyone should be advised to take B12 or folate without proper investigation first because it can make the whole picture very confusing and risk making your health very much worse. B12 deficiency and pernicious anaemia are serious (as I'm finding out) and supplementing skews the tests so that you will not get a diagnosis (and it is hard enough to get doctors to consider it anyway). I am taking methyl B12 and folate because I had already supplemented for years without knowing better so am getting much worse and struggling to get a diagnosis. If you haven't already started I'd say no, not without good qualified advice. High doses of folate are not a good idea. And it could be oestrogen, copper, magnesium, riboflavin.... I quote 'There is no standard approach to effectively assess the impacts of the MTHFR gene mutation, and automatic prescriptions based on diagnoses of the mutation can be detrimental' You can overmethylate, you need to start slow, and sometimes methyl forms can make you worse - depends what else you are dealing with I'm afraid.
I see what you are saying. You should withhold B12 for 3 days before testing. B vitamins are difficult for the body to hang onto which I assume means storing somewhere so overdosing doesn't seem to risky.
So far, there seems to be no definitive calculation for folate but I'll read up more
on it. It would be wonderful to determine all the implications for chronic disease and it seems it is getting closer.......if you can afford it. Thanks again, your comments are always helpful.
Just in case, the PA forum on here regularly states do not start supplementing until testing complete. You need to be off for a good bit longer than 3 days, or so I understood. And folate will mask an anaemia so it won't get picked up but not stop neurological damage continuing due to lack of B12. Proceed with care! Best wishes
Hi, I'm UK. I don't know much about Lyme, sorry (I know what you mean about thyroid and hormones though!). Micki Rose would still be my first point of call, have a look at purehealthclinic.co.uk/heal... and purehealthclinic.co.uk/2017... I am sure there is more, I just searched Lyme on the website. Have a look at Contact and Support Options and maybe email her for a view on how to proceed. She is very easy to talk to and has had lots of health issues herself so will know where you are coming from. Best wishes
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Help with Lab tests - first timer
GP / lab won’t test FT4 !!
The lab ignored the doctor's test request
HELP please with new 'private' blood test results compared to GP's. 
New private blood test labs Sussex/Surrey.
