Has anyone experienced that their antidepressan... - Thyroid UK

Thyroid UK

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Has anyone experienced that their antidepressants work a lot better when taking levothyroxine or other thyroid meds for hypothyroid?

16 Replies

Anybody?

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16 Replies
Batty1 profile image
Batty1

Yes, it caused my thyroid labs to plummet into Neg territory and soon as I stop it bounced back about 6 weeks later at next lab.

SilverAvocado profile image
SilverAvocado

Feeling depressed can be a symptoms of being hypothyroid, so getting it properly treated will probably improve things in itself.

Batty1 profile image
Batty1 in reply toSilverAvocado

I don't know silver avocado these doctors seem to think depression is to blame for everything and your diagnoised hypothyroidism isn't the problem. I went to Endo complained about constant tiredness and he sent me for sleep study and my LDL levels are crazy high and seemed to increased when my dose changed and Endo said nope not thyroid related although the scientific evidence says otherwise.

We are like hamsters stuck in a wheel that never seems to stop until you fall off. Just crazy!

HashiFedUp profile image
HashiFedUp in reply toSilverAvocado

I agree completely. Thyroid probs cause depression. So you may fine that with thyroid meds your depression lifts anyway.

vocalEK profile image
vocalEK in reply toSilverAvocado

Thyroid problems also cause high cholesterol. medicalnewstoday.com/articl...

Doctors should test thyroid function of those with high cholesterol and treat the hypothyroidism first. This can "cure" the high cholesterol and avoid giving the patient statin drugs that cause nasty side effects. Muscle damage is more likely from statins in those who are hypothyroid.

Sarahlouise1980 profile image
Sarahlouise1980

No, but Sertraline did make my Levothyroxine less effective over time and I eventually needed to increase my dose and decrease it again when I stopped taking Sertraline x

greygoose profile image
greygoose

Depression is a symptom, not a disease. It's not that taking thyroid hormone replacement makes your anti-depressant work batter, it's that raising thyroid hormone levels gets rid of symptoms like depression.

tzracer profile image
tzracer in reply togreygoose

👍 My thoughts exactly, saved me typing it.

adin profile image
adin

I took Lexapro(5mg) some time ago to ease my anxiety and it really helped me. I took my levo+T3 in the morning and ssri in the evening. The only problem was that I gained weight and decreased my ft4 value, maybe they're related.

greygoose profile image
greygoose in reply toadin

Taking T3 will always decrease your FT4. :)

adin profile image
adin in reply togreygoose

So, now I understand why... I don't have depression but my anxy is on the roof

greygoose profile image
greygoose in reply toadin

Anxiety is a hypo symptom - like depression - so maybe you're under-medicated.

adin profile image
adin in reply togreygoose

I don't think so, why when I try to raise my levo dose or T3 I get anxiety ? I know what you're saying (Anxiety is a hypo symptom) but in my case I have anxiety if I raise the dose, too.

greygoose profile image
greygoose in reply toadin

Well, yes, you can get anxiety if your over-medicated, but my point was, it's to do with the thyroid, not a separate disease.

There are several studies that show that. I suspect that a lot of "depression" is actually low thyroid hormones, since there are no physical tests for depression and the silly questionnaire would have almost anyone who lives a normal life in the modern world down as at least mildly depressed

vocalEK profile image
vocalEK in reply toAngel_of_the_North

And fighting the symptoms of hypothyroidism can definitely make you feel depressed.

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