Feeling wired

[mrneduc]

I’m not aware of being over medicated but recently I’ve been feeling what I best describe as ‘wired ‘ on the edge, stressed for no reason and unwell. I’m wondering if others have this and in what circumstances?

[jamesal0]

take 25 mcg off your daily dose for 7 days - see if it helps

[Lynl in reply to jamesal0]

Please don’t try to switch somebody’s medication because that could cause a reaction that they are not used to if you are not a doctor or that person’s doctor

[NWA6 in reply to Lynl]

Lynl!! This is a board of ‘non’ professionals! (Even those who are qualified can’t give advise in a professional capacity) I have had more ‘advise’ from these members than from my so called professionals. Please don’t shoot down someone’s perception of what might be wrong or what might work. We are all trying to help each other and ‘experiment’ because nobody else is gonna help us.

[Lynl in reply to NWA6]

I in no way tried to play doctor, I was commenting on someone telling this person yo cut down on meds and I said to check with doctors on that . I give no medical advice . I was trying to help so they would not listen to the one who said cut the meds

[Lynl in reply to NWA6]

Look at jamesal0 advice

[Lynl in reply to NWA6]

I think you commented on the wrong person have you looked at the other comments below

[NWA6 in reply to Lynl]

No I was commenting on your reply. I think you’ll find that the majority of forum members would take advise from other forum members before they ever took advise from Dr’s. Dr’s are the Bain of our lives!

We are all grown adults here and should be treated as such. Something which out Dr’s don’t do. They treat us like children. They do not offer any choice. When forum members post ‘advise’ on this forum it is up to the poster to investigate and work out if that’s the direction they want to go.

I stand by what I said in reply to your post. No one wants to consult their Dr because the Dr’s are rubbish! That’s why they’re on this forum.

[Lynl in reply to NWA6]

Oh , I get it, yes I go to the doctors for so many health anxieties and sometimes feel they blow me off , I do have a couple that have empathy and try to re assure me . But I do understand what you meant. It does concern me if someone takes advise that might not be good for them , like medication , you have to be very careful when cutting back to stopping .

[NWA6 in reply to Lynl]

🤗 not all advise that we get on this forum is corrrect or suitable for that individual because we are all individuals. But if we warn each other off from and advise because ‘we’re not medically trained’ them were dies that leave us? Back to thinking only Dr’s know what they’re doing and I have first hand experience of Dr’s keeping me ill because they are not treating me as an individual.

Anyone on this forum MUST take control of their own health. They MUST understand that none of us can give qualified or professional advice. We’re all just a bunch of lay people trying to help each other out. And I’d love to know the actually % of forum members who have become optimally treated from ‘advice’ from this forum. I bet it’s a staggering amount and I bet it is a much higher % than those who sought their Dr’s counsel.

[Lynl in reply to NWA6]

True. But I do know if I cold turkey what I take j could go into a seizure , I have to wean off snd I’m actually doing that against doctors orders. Slowly though .

[SlowDragon Administrator]

Suggest you get full Thyroid and vitamin testing BEFORE considering changing your dose

Anxiety can be due to being under medicated or over medicated or low vitamin levels

For full Thyroid evaluation you need TSH, FT4 and FT3 plus both TPO and TG thyroid antibodies tested. Also important to test vitamin D, folate, ferritin and B12

Low vitamin levels are extremely common, especially if Thyroid antibodies are raised

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water . This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip, best not mentioned to GP or phlebotomist)

Last Levothyroxine dose should be 24 hours prior to test, (taking delayed dose immediately after blood draw).

If/when also on T3, make sure to take last dose 8-12 hours prior to test, even if this means adjusting time or splitting of dose day before test

Is this how you do your tests?

Private tests are available. Thousands on here forced to do this as NHS often refuses to test FT3 or antibodies or all vitamins

thyroiduk.org.uk/tuk/testin...

Medichecks Thyroid plus ultra vitamin or Blue Horizon Thyroid plus eleven are the most popular choice. DIY finger prick test or option to pay extra for private blood draw. Both companies often have special offers, Medichecks usually have offers on Thursdays, Blue Horizon its more random

[mrneduc in reply to SlowDragon]

Thankyou. I will get more tests done via Medicheck. I’m not optimal but in range regarding TSH, T3 and T4. Cortisol is fine. No idea about vits and minerals. I don’t have Hashimotos but since having most of thyroid removed 2.5 years ago I’ve never felt so unwell.

[SlowDragon Administrator in reply to mrneduc]

You say they're not optimal.......So what are your most recent TSH, FT3 and FT4 results and ranges?

[m1southbound in reply to SlowDragon]

Mid Aug 2019 results

TSH 2.25 (0.27-4.2)

FT3 4.43 (3.1-6.8)

FT4 17.7 (12-22)

[SlowDragon Administrator in reply to m1southbound]

So FT4 is 57% through range

FT3 is only 35% through range

Useful calculator for working out % through range

chorobytarczycy.eu/kalkulator

The aim of Levothyroxine is to increase the dose slowly in 25mcg steps upwards until TSH is under 2 (many need TSH significantly under one) and most important is that FT4 in top third of range and FT3 at least half way in range

[m1southbound in reply to SlowDragon]

Thankyou. I must sort this out and aim for better levels. This is great info. My Dr tends to let me decide how much I take!

[HLAB35]

A tired but wired feeling could be because you have some conversion issues, but you need an up to date panel to check. A minor conversion issue may be helped by improving vitamin and mineral status... but it really depends on what this looks like for you... it could be you're either very low or very high in b12, for example. If you have low vitamin d status it can also indicate a magnesium deficiency which would explain why you can't relax.

energizeorganics.com/cortis...

P.S. Just added a link that may help you understand the connections.

[m1southbound]

I did have a cortisol saliva test about a year ago which was normal. I try to cover most of the bases but not sure about minerals etc. I don’t know why I feel so awful . I’m taking self sourced T3 only 1/4 tab (6mg) each morning but I get palpitations almost every day. I’m not sure if it’s thyroid related as I’m on long term antibiotics which can affect the heart . Never had palps before my thyroid op and Levo replacement so I’ve assumed it’s in some way related. Cardiologist (year ago) says no underlying heart disease - my week is taken up with medical appointments- family think it’s a joke but it’s not

[SlowDragon Administrator in reply to m1southbound]

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water . This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip, best not mentioned to GP or phlebotomist)

Last Levothyroxine dose should be 24 hours prior to test, (taking delayed dose immediately after blood draw).

If/when also on T3, make sure to take last dose 8-12 hours prior to test, even if this means adjusting time or splitting of dose day before test

Is this how you do your tests?

The trouble with taking a single dose of a tiny amount of T3 is it may suppress thyroid output.

Many people (including myself) need 3 small doses of T3 roughly eight hours apart.

Palpitations can be due to being under medicated

[m1southbound in reply to SlowDragon]

I do all my tests as you suggest. I never knew about the small dose of T3. So it may be better to up the T3 by taking a small dose x2 or even 3.? Maybe worth trying. Obviously very slowly . Do you take Levo as well?

[SlowDragon Administrator in reply to m1southbound]

Yes.....full details on my profile

20mcg Liothyronine per day - 10mcg at 7am, 5mcg at 3pm and 11pm

125mcg Levothyroxine - I split Levothyroxine too. 100mcg at 11pm and 25mcg at 7am

All four vitamins optimal by continuously supplementing and absolutely strictly gluten free and soya free

Positive for Heterozygous DIO2 gene variation

Only made progress, by joining here and learning importance of regular full Thyroid and vitamin testing and just how prevalent gluten intolerance is.

[mrneduc in reply to SlowDragon]

Thankyou so much for this info. Quite a regime to follow but worth it to feel well. I’ve tried to adjust to feeling under par or downright ill but I want to feel well so I will make the effort. Been in a kind of torpor for last 18 months

[SlowDragon Administrator in reply to mrneduc]

I was virtually immobile on just Levothyroxine and before improving vitamins and addressing hidden food intolerances

Now can lead absolutely normal life,

I wear a Fitbit- 10,000 steps minimum per day average. Often far more

[m1southbound in reply to SlowDragon]

Seems T3 is the magic Ingredient + vits etc . So glad you have your life back. I’m going to start by adding in some more T3 maybe late afternoon. Unfortunately all the T3 supplies I have are out of date. Still seems to work though. Feel a bit of hope at last

[Alexkjones]

I think it’s the adrenal system maybe.

[NWA6]

Yes I’ve had this for about a 6mth period. I raised my T4 but didn’t know at the time that I had conversion issues. I had periods over a 10yr timeline where raising my T4 would help me get enough converted but then that stopped working a few years ago. My body tried to carry on until it ground to a halt.

This is a good time to get a full Thyriod and Vit/min check done to see exactly where you’re at. You’ll understand more when you see the results and then you’ll know what changes and/or reading to do.

[m1southbound]

Do you take T3?

[SlowDragon Administrator in reply to m1southbound]

Were you asking NWA6 This question?

You actually replied to yourself

[m1southbound in reply to SlowDragon]

I have two accounts apparently and I’m a bit confused. I thought I’d deleted one of them months ago but when I rejoined recently it seems to have conflated both. My most up to date is m1southbound (silly name I know) I will try and sort out again

[pennyannie]

Hello mrneduc going M1southsound :

Just as a point of reference a fully functioning working thyroid would be supporting you daily with approximately 100 T4 + 10 T3. I just think if there has been a medical intervention and the thyroid removed or ablated in situ with RAI both these vital hormones should be on the patients prescription for if, and probably when needed.

T3 is said to be about four times as powerful as T4 and is the active hormone that your body runs on. Your body needs to convert T4 into T3 and this can be compromised if your ferritin, folate, B12 and vitamin D are not optimal.

I am with Graves Disease, post thyroid ablation with RAI and am now self medicating with Natural Desiccated Thyroid. This was the treatment for hypothyroidism, for over 100 years, prior to the 1960's and the arrival of Big Pharma, blood tests, ranges, and a patented medication called Levothyroxine.

[m1southbound in reply to pennyannie]

I’ve tried NDT and sadly don’t feel great in it. My best is probably the T3/4 combo. I don’t think I’m having enough T3 but I’m on Levo 100/125 alternate days. I will try an extra 5 mg of T3

Like my new user name- trying to work out how to sort it

[pennyannie in reply to m1southbound]

Ok then, just remember everything is approximate and I think you loose a certain amount of any dose through digestion. It's not an exact science, and yes, the fixed ratio of T3/T4 in NDT isn't everybody's cup of tea.

Pity there's no satnav to confirm if you're going in the right direction up or down on the M1.

[m1southbound in reply to pennyannie]

I’m a Londoner moved north and always hankerings g for home

[pennyannie in reply to m1southbound]

I moved to Cornwall and long for London !!

[m1southbound in reply to pennyannie]

I understand- the Dales are beautiful but the small lanes with passing places make me long for the M25 - sad!!

[pennyannie in reply to m1southbound]

Golly, you're still awake - I hope not " wired " -

well yes, Cornwall is very scenic and all that, but I miss the immediacy of London

a transport system, and the 21st century facilities and people I found in the capital.

[m1southbound]

I understand re the immediacy and range of facilities in London. Miss that very much. I was feeling very wired last night and got to sleep at approx 3am. I’m going to increase my T3 starting with an extra 5mcg at midday starting tomorrow- it could go either way re my well being