Heart in pain from high dose levo : Heart... - Thyroid UK

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Heart in pain from high dose levo

Pinktijen profile image
3 Replies

Heart problems. I'm on a high suppression dose of levo and I am sick of my heart being strained and hurting. Since Feb.

Finally saw an Endo today who has reduced my dose.

My friend has an apple watch thing and did my heart rate and the mini ECG was totally abnormal!!!??? I am now panicking that I have done some damage.

I was on thc too so sent my heart racing even more.

How long after reducing my dose will i hopefully recover?

Anyone else had this happen? What should I do? I was on 125 levo...then 100 and now today will drop to 87.5.

History...had thyCan. TT Feb.

Fsh 81.1

Free t3 5.2 (3.1 - 6.8)

Free t4 29 (11-22)

Tsh 0.03 (0.27 - 4.20)

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SlowDragon profile image
SlowDragonAdministrator

For full Thyroid evaluation you need TSH, FT4 and FT3 tested. Also EXTREMELY important to test vitamin D, folate, ferritin and B12

Have you had vitamin levels tested?

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and fasting. This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip, best not mentioned to GP or phlebotomist)

Last Levothyroxine dose should be 24 hours prior to test, (taking delayed dose immediately after blood draw).

Is this how you do your tests?

Private tests are available. Thousands on here forced to do this as NHS often refuses to test FT3 or antibodies or all vitamins

thyroiduk.org.uk/tuk/testin...

Medichecks Thyroid plus ultra vitamin or Blue Horizon Thyroid plus eleven are the most popular choice. DIY finger prick test or option to pay extra for private blood draw. Both companies often have special offers, Medichecks usually have offers on Thursdays, Blue Horizon its more random

Your FT3 is nowhere near top of range

Dr Toft, past president of the British Thyroid Association and leading endocrinologist, states in Pulse Magazine,

"The appropriate dose of levothyroxine is that which restores euthyroidism and serum TSH to the lower part of the reference range - 0.2-0.5mU/l.

In this case, free thyroxine is likely to be in the upper part of its reference range or even slightly elevated – 18-22pmol/l.

Most patients will feel well in that circumstance. But some need a higher dose of levothyroxine to suppress serum TSH and then the serum-free T4 concentration will be elevated at around 24-28pmol/l.

This 'exogenous subclinical hyperthyroidism' is not dangerous as long as serum T3 is unequivocally normal – that is, serum total around T3 1.7nmol/l (reference range 1.0-2.2nmol/l)."

You can obtain a copy of the articles from Thyroid UK email print it and highlight question 6 to show your doctor

please email Dionne at

tukadmin@thyroiduk.org

Professor Toft recent article saying, T3 may be necessary for many. Note especially his comments on current inadequate treatment following thyroidectomy or RAI

rcpe.ac.uk/sites/default/fi...

It's likely your FT3 will drop significantly on reduced dose of FT4

Many patients after thyroidectomy or RAI need addition of small dose of T3

Email Dionne at Thyroid Uk for list of recommended thyroid specialist endocrinologists who will prescribe T3

20% Patients with no thyroid can not regain full health on just Levothyroxine

ncbi.nlm.nih.gov/pmc/articl...

Low TSH no heart issues

academic.oup.com/jcem/artic...

In summary, patients on long-term T4 with either an increased serum TSH (>4 mU/liter) or a suppressed TSH (<0.03 mU/liter) have an increased risk of cardiovascular disease, dysrhythmias, and fractures when compared with patients with a TSH within the laboratory reference range. Patients with a low, but not suppressed, TSH (0.04–0.4 mU/liter) had no increased risk of these outcomes in this study.

greygoose profile image
greygoose

What was the dose of levo you call 'high'? 125 mcg levo? And, are those results on 125 mcg levo? Sorry, for the questions, but it's not clear in your post.

So, assuming those results were on 125 mcg levo, your FT4 is high over-range, but as you are a poor converter, your FT3 is only about mid-range.

T3 is the active hormone, not T4 (levo), so that is the one that would 'hurt' your heart if it were over-range. It isn't. High T4 will not have any effect on your heart. So, it is not the 'high' dose of levo that has caused your heart pain either directly or indirectly.

Therefore, if you have a problem with your heart, it is due to something else other than the levo. (What is THC?) So, it is doubtful that reducing your levo will stop your heart hurting.

On the other hand, reducing your levo to such an extent will probably make you ill in other ways, because your FT3 will also reduce. So, it's probably not a good idea.

bantam12 profile image
bantam12

How do you know your ecg is abnormal? It's extremely difficult to read ecg's properly and those done on a watch are known to be inaccurate due to interference.

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