Antibodies : Hi just wondered if anyone could... - Thyroid UK

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Antibodies

Button11 profile image
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Hi just wondered if anyone could explain the antibodies to me please. My tsh,t4 and t3 have always been in range but this was a private test where they also carried out antibodies test.

Also keep having low vit d so on supplements now don’t know if there is link

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SlowDragon profile image
SlowDragonAdministrator

Your antibodies are slightly high this is Hashimoto's, (also known by medics here in UK more commonly as autoimmune thyroid disease).

Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone working

Low vitamin D is EXTREMELY common with Hashimoto's

How low was vitamin D and how much have you been prescribed?

It's trial and error what dose each person needs.

Once you Improve level, very likely you will need on going maintenance dose to keep it there. You will need to self supplement this, NHS doesn't prescribe ongoing maintenance dose

Aiming to improve vitamin D to at least 80nmol and around 100nmol may be better . Vitamin D mouth spray by Better You is good as avoids poor gut function

Retesting twice yearly via vitamindtest.org.uk

Local CCG guidelines

clinox.info/clinical-suppor...

Have you also had B12, folate and ferritin tested?

If not get these done

What were TSH, FT3 and FT4 results and ranges?

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

Ideally ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first

Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

scdlifestyle.com/2014/08/th...

drknews.com/changing-your-d...

restartmed.com/hashimotos-g...

For full Thyroid evaluation you need TSH, FT4 and FT3 plus both TPO and TG thyroid antibodies tested. Also extremely important to test vitamin D, folate, ferritin and B12

Low vitamin levels are extremely common, especially if Thyroid antibodies are raised

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and fasting. This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip, best not mentioned to GP or phlebotomist)

Private tests are available. Thousands on here forced to do this as NHS often refuses to test FT3 or antibodies or all vitamins

thyroiduk.org.uk/tuk/testin...

Medichecks Thyroid plus ultra vitamin or Blue Horizon Thyroid plus eleven are the most popular choice. DIY finger prick test or option to pay extra for private blood draw. Both companies often have special offers, Medichecks usually have offers on Thursdays, Blue Horizon its more random

Link about antibodies and Hashimoto's

thyroiduk.org.uk/tuk/about_...

thyroiduk.org.uk/tuk/about_...

List of hypothyroid symptoms

thyroiduk.org.uk/tuk/about_...

Button11 profile image
Button11 in reply to SlowDragon

SlowDragon waw thank you for all the info I’ll read up on all the links listed.

My vit d was 36.2 at Christmas he told me to just get over the counter vit d tablets which are 1000iu I take once a day. I’ve had gut problems for a while now being diagnosed with ibs and possible endometriosis.

My b12 slowly falls and in past 4/5 years I’ve not seen it above 400 now it’s at 229 (Xmas) and he wants a re test (which I’m getting next week) but 2016 I had injections after it fell to 188. Then year after I had low folate but none seem to fall drastically just very slowly over time.

This antibodies test was done 2016 privately (blue horizon) and my tsh at the time was 3.75 range 0.27-4.2, t4 was 14.29 range 12-22 and t3 4.3 range 3.1-6.8.

Last tsh was 2.3 range 0.35-4.94 my doctors never show t3&t4 just the tsh

I’ve stopped eating dairy as I felt that was upsetting my stomach and my partner is gluten sensitive so we eat a gf diet too.

My bloods are at 9.50 and I don’t know if they’ll just do the b12 as requested or the full bloods again

SlowDragon profile image
SlowDragonAdministrator in reply to Button11

The lower vitamins drop, the lower TSH goes, regardless of how hypothyroid you actually are

Getting vitamins optimal is essential

Highly likely that your vitamin D dose is inadequate

Aiming to improve vitamin D to at least 80nmol and around 100nmol may be better

Vitamin D mouth spray by Better You is good as avoids poor gut function of Hashimoto's

It's trial and error what dose each person needs. But with Hashimoto's we frequently need more than average

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Suggest you get vitamin D tested now

And Retesting twice yearly vitamindtest.org.uk

Local CCG guidelines clearly state GP should have prescribed 1600iu per day for 6 months

clinox.info/clinical-suppor...

Government recommends everyone supplement October to April

gov.uk/government/news/phe-...

Also read up on importance of magnesium and vitamin K2 Mk7 supplements when taking vitamin D

betterbones.com/bone-nutrit...

articles.mercola.com/sites/...

healthy-holistic-living.com...

sciencedaily.com/releases/2...

articles.mercola.com/sites/...

betterbones.com/bone-nutrit...

Do NOT supplement any vitamin K if you take any blood thinning medication

drsinatra.com/vitamin-k2-su...

Vitamin C and bones

healthimpactnews.com/2018/d...

The importance of sunshine

outsideonline.com/2380751/s...

Push GP got futher testing on low B12 and low folate

Ask advice on PAS healthunlocked

If you can't get B12 injections as treatment then will need to start self supplementing

Supplementing a good quality daily vitamin B complex, one with folate in not folic acid may be beneficial.

You may need daily sublingual B12 as well, certainly initially. Usually recommended to get a bottle of 5000mcg B12. When these are finished get 1000mcg dose

After a year you may be able to cut the B12 supplements out. Likely to need ongoing B complex

chriskresser.com/folate-vs-...

B vitamins best taken in the morning after breakfast

Recommended brands of B complex on here are Igennus Super B complex. (Often only need one tablet per day, not two). Or Jarrow B-right

If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before any blood tests, as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

You need ferritin tested

As vitamins improve you may see TSH rise so that you can get GP to see you need Levothyroxine

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