Recording FT3 and FT4 reference ranges - Thyroid UK

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Recording FT3 and FT4 reference ranges

diogenes profile image
diogenesRemembering
7 Replies

On this forum there are several different ways of recording reference ranges for FT3 and FT4 which can cause the utmost confusion.

Just for the record, I compare the world's (Incl UK) ranges and the US ones as both come on to this forum with their own ranges:

Normal range for FT3 in pmol/L (UK and everywhere else sensible) 3.5-7.

In the USA 2.0-4.4 pg/ml

Normal range for FT4 in pmol/L (UK and everywhere else sensible) 10-25 pmol/L

In the USA 0.9-1.8 ng/dl

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diogenes profile image
diogenes
Remembering
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7 Replies
Hennerton profile image
Hennerton

My labs in the Thames Valley are different.

T3 is 3.9 - 6.7 and T4 is 12 - 22.

They have been like this for years. Are you familiar with these ranges?

diogenes profile image
diogenesRemembering in reply to Hennerton

Yes, it's not the exact ranges for the different ways (pmol/L. ng/dl etc) of expressing that I'm dealing with, but the actual basic difference in the units used and the confusion it causes to people trying to respond to posters. Eg in calculating FT4/FT3 ratios.

humanbean profile image
humanbean in reply to diogenes

I think I read something recently that you've written saying that the American units of measurement make it impossible to work out a Free T4/Free T3 ratio because they aren't in the same units, and are actually measuring something in a completely different way from the way that UK measurements are. Something to do with the molecular weights?

Can the American units of measurement be converted to pmol/L ?

Angel_of_the_North profile image
Angel_of_the_North in reply to humanbean

Easier just to work out how far through the range each one is and if the FT3 % age is way lower than the FT4 % age you have a conversion problem. If the FT3 is higher in range than FT4 and TSH is over 3, you have the beginnings of hypo. Not really sure if anything else really matters

humanbean profile image
humanbean in reply to Angel_of_the_North

Very good point!

BeachHut profile image
BeachHut

Not sure if I am missing something but searching for a converter on the internet I get the following, which would suggest you have the American T3 and T4 transposed.

3.5 pmol/L = 0.95 pg/mL

7 pmol/L = 1.91 pg/mL

10 pmol/L = 2.72 pg/mL

25 pmol/L = 6.81 pg/mL

diogenes profile image
diogenesRemembering in reply to BeachHut

The FT4 I quoted for the US is in ng/dl not pg/ml. You can see the horrible confusion all these different nomenclatures produce.

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