Help converting numbers!: I don’t do numbers... - Thyroid UK

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Help converting numbers!

Murphysmum profile image
9 Replies

I don’t do numbers, ever.

But really not now with my brain fog.

I’m trying to compare my recent B12 levels with ones done earlier in the year. My recent medichecks result was Active B12 66.6 pmol/L (37.50-188.00) and my previous result was in May, B12 418ng/L (180-2000 ng/L).

Difference between a nanomole and a picomole?? 🤯🤯

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Murphysmum profile image
Murphysmum
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SeasideSusie profile image
SeasideSusieRemembering

Murphysmum

You can't compare Active B12 with Serum B12, they're measuring different things.

Your Active B12 is actually rather low and it's suggested anything below 70 should be tested for B12 deficiency

viapath.co.uk/our-tests/act...

Murphysmum profile image
Murphysmum in reply toSeasideSusie

Aha!

Thank you susie, brilliant as always!

I am beginning to wonder if I should push the PA thing with the gp. I’m on another increased dose of levo and still the same symptoms remain. I’m wondering if I’m chasing down the wrong track.

Do you think it would be worth asking the gp... again?

Edited to add, I’ve been supplementing with b12, sublingual and spray and b complex since february....

SeasideSusie profile image
SeasideSusieRemembering in reply toMurphysmum

Check here for signs of B12 deficiency

b12deficiency.info/signs-an...

If you have any then I would ask GP to test.

However, looking at your previous post you are supplementing with a B Complex and the folate in that (or folic acid probably in the H&B one) will mask signs of B12 deficiency so you will have to think about symptoms prior to supplementing as well as current ones.

Reading through that previous post, I agree that all your nutrients need improving - Ferritin, Folate as well as B12 - but you have no Vit D result and that is important to know where you are with that.

I also agree that your conversion isn't as good as it should be, and that you don't really need an increase in Levo.

And as your raised TPO antibodies confirm autoimmune thyroid disease, aka Hashi's, are you going to address that with a strict gluten free diet. It seems that you are already taking selenium, hopefully not H&B as their own brand supplements tend to be pretty naff.

Murphysmum profile image
Murphysmum in reply toSeasideSusie

Thanks susie.

I did have far worse symptoms at the beginning of this year and probably up until around May/June. These included vertigo, pins and needles, numb parts of feet/toes etc. I still have many symptoms that I was 100% assuming were hashis: tinnitus, muscle weakness, vision/focussing problems, headaches and dizziness.

What I keep coming back to though is, up until September last year I had been hypo/hashis for about 13 years, treated with levo and never had any issues. With hindsight, I was a bit lax with when I took my levo - something I know now was really stupid if not dangerous. However, I think serious stress was what kicked everything off last year. So hence I keep wondering why is it I can’t get back to normal?

I have been continually supplementing with b complex, b12, c, d (+k2), zinc/selenium (not h&b!) and magnesium since feb this year. I’ve recently added iron, omega 3 and milk thistle to this. Admittedly, the b complex was h&b and therefore folic acid but I’ve recently replaced this with the Igennus b complex.

I’m reluctant to go gf... if I’ve got everything else to where it needs to be and I’m still having symptoms then i will give it a try but again I come back to “it wasn’t a problem before..” so why should it be that particularly?

I should also add I try to remember to take my betaine/hcl with my evening meal at least each day, but I do forget!

Do we think I should pursue the low b12 and folate with the gp?

SeasideSusie profile image
SeasideSusieRemembering in reply toMurphysmum

Do we think I should pursue the low b12 and folate with the gp?

These included vertigo, pins and needles, numb parts of feet/toes etc. I still have many symptoms that I was 100% assuming were hashis: tinnitus, muscle weakness, vision/focussing problems, headaches and dizziness.

Have you checked the list of signs and symptoms of B12 deficiency? I think you will find enough of these symptoms listed there to warrant further testing.

I'm not Hashi's so can't speak from experience, but many members with Hashi's benefit from a gluten free diet.

Murphysmum profile image
Murphysmum in reply toSeasideSusie

When I showed that list to my gp previously she just said “your levels are fine”.

I think the fact that I’m still moaning more than 6 months later after supplementing every day wpmight warrant some more investigation too!

SeasideSusie profile image
SeasideSusieRemembering in reply toMurphysmum

When I showed that list to my gp previously she just said “your levels are fine”.

With B12 deficiency/pernicious anaemia, it's symptoms that matter not numbers. There are people who have had Serum B12 level in the 300s who have ended up being prescribed B12 injections, so it's not down to numbers. Maybe see a different GP. One who actually cares about how you feel.

Murphysmum profile image
Murphysmum in reply toSeasideSusie

Mmmmm.

Easier said than done but I will go armed with much more knowledge this time thanks to this forum.

Gambit62 profile image
Gambit62

the units above are actually nanograms and picomole

one is measuring the weight of B12 and the other is measuring the number of B12 molecules.

Conversion for B12 is to multiply pmol/L by 1.355 to get the equivalent ng/L

The multiplier for other chemicals will be different

As Seaside Suzie says the two tests can't be directly compared even once you have converted the units as they are testing different things, though in general active B12 will be about 20% of total serum B12.

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