I've been taking thyroxine since my early childhood. It start with having to cut a 50microgram tablet in half. And no it wasn't easy.
But back to my question I've been on the new formulation Levothyroxine for 6 weeks and I don't feel they are as affective.
It could be just me but to find a clear answer has anyone else felt that the formulation is not as effective.?
Thanks
Angelone
What new formulation?
Are you in the UK?
What brand were you taking, what have you been changed to?
I live in the UK. Have been taking thyroxine all my life. Then it changed to levothyroxine .
However, the last two months I've been given new formulation. The chemist said it no longer contained lactose.
I think the company name is teva or it could be tevn its a funny logo.
I've been on a 100microgram dose for 12 years now. However, I don't feel the same. Hard to explain. I little more tired headache and sweating. ( although that could be my age lol)
Ask the doctor to write a new prescription and check with the pharmacist that they can supply a different formulation such as Actavis. Many people have found problems with TEVA. It is the only lactose free levothyroxine but no good if it doesn't work for you. If your present pharmacist cannot supply another brand then find a different pharmacy that can.
Do an MHRA yellow card report to help maintain quality levothyroxine. yellowcard.mhra.gov.uk/
Thank you that helps. The chesmist (well the person who handed over my medication ) told me they were the same. To which I answered if they were the same it wouldn't have new formulation on it. Are
They cheaper by any chance?
I don't know if they're cheaper. TEVA had its licence withdrawn around 2012 as their levothyroxine was poor quality and not bioequivalent to others. So they reformulated and were granted a licence by the MHRA and their levothyroxine is now available as a lactose free variety and presumably of sufficient quality for the medical regulators. Howevver, a lot of people on this forum reported problems when they switched. Everyone is different and it might be the fillers that don't suit you.
Angelone
Thyroxine is Levothyroxine.
It appears you have now been changed to a lactose free brand which is Teva.
Were you on Teva before, but before they reformulated to lactose free?
If you were doing well on a normal (not lactose free) levothyroxine before then all other brands will possibly suit (providing you don't react to any fillers).
UK brands are
Actavis
Almus from Boots (which is Actavis rebranded)
Northstar - again this is Actavis which I believe is rebranded for Lloyds pharmacies and former Sainsburys pharmacies
Wockhardt
Mercury Pharma - also sometimes branded as Eltroxin I believe
Many people have had adverse reactions to the new lactose free Teva. Do a yellow card report as Nanaedake has mentioned, and ask your pharmacist for a different brand next time you take your prescription in, if you can't have a different brand get your prescription back, ring round other pharmacies and find one that can supply another brand.
Thank you so much. I gave the tablets a try as they tried me on them before I thought it might be related to the onset of the change lucky me lol. Its the chemist I need to speak to. So I thank you for your advice. X
This post may answer your question 
healthunlocked.com/thyroidu...
I started on levothyroxine recently. First pack was the new Teva one. 2 tablets in....SO unwell. Changed to Mercury Pharma. No adverse effects so far. Teva contains Mannitol (e421) as a filler which is thought to be one possible culprit along with acacia. Neither of those are in Actavis or Wockhardt which anecdotally appear to be more widely tolerated on here from what I can see.
Thank you. My chemist tried to tell me they were the same. Affraid I was a tad sarcastic as it clearly states new formula on the box. However,I've now found out so much from this site. I will be checking if t
Well founded sarcasm is always a winner 
I've learnt so much from this forum in the few short weeks since I was finally diagnosed with Hypothyroidism, which I now realise I have probably been suffering with for years. I would never have got to the bottom of it had it not been for this forum and it's members who have been so generous with their time and knowledge.
Hypothyroidism is a tricky condition . I now have a new prescription and a different brand of levothyroxine. So hopefully I will start feeling better .
Its shocking that these drug companies get away with providing sub standard drugs.
Hundreds of people have had terrible reaction to Teva
healthunlocked.com/search/t...
Take it back to pharmacy tomorrow and get your normal brand
Also put in a yellow card
Last week I was told by three pharmacies that they all stock Teva only now because it is cheaper 
However I did manage to find one that was prepared to order an alternative so go elsewhere if necessary.
From what I've seen posted TEVA appears to work well for people you can't take Lactose so it's presumably doing what it is supposed to do yet it's being given to anybody and everybody! Go back to whatever you are happy with then asked the pharmacy to but that on your notes and if they are unwilling to do that then get your doctor to request _______ only. They should take note of that but if they still argue they can't do it then take back your prescription and fine somewhere that can. When I was advised by the pharmacy to stick to one brand as I was being given whatever they had each month and I could tell the slight different in potency-the formulas were made to a greater intolerance back then, I was asked which I preferred so I said testing can get me to the dose which is best for me so which brand were they sent most frequently. They suggested the one that has now become Mercury Pharmacy and I tweaked my dose to take that one and as asked got my doctors to put it on my first subscription. They also suggested I worked with 4 weeks in hand in case they had a problem getting it at anytime though told me doctors most probably wouldn't do that so get the request in 1-2 days earlier each month till I had enough in hand. If your GP adheres to the exact day then you may have to 'lose' a packet on holiday. Thankfully by being titrated against a more common brand it was always available but that was along time ago now.
Absolutely I have been on the new formulation for roughly 3 weeks now feeling so tired asked doc for bloods to check my thyroid as I too feel it’s not working as it was..
I persevered for six weeks but felt tired, headache and low mood. I spoke to my doctor and he gave me a new prescription. I am now back on the mercury pharmaceutical brand. I'm starting to feel a little better. Please ask your doctor to give you a new prescription.
I am filling out a yellow card as I found out from this site that teva had their license revoked previously for providing low quality levothyroxine.
I'm sorry for my late response. Hope this helps and that you get a new prescription let me know.
Take care
I have been taking thyroxine for nearly 30 years, and have been stable on 125mcgs Activis for a long time. My GP practice switched to the new Teva formulation some time ago. In Jan 2017 my TSH was 6.01 against 4.5, and my free T4 was lower than normal. My GP left it as it was as I have Hashimoto's. I soon felt unwell with appetite problems, but it improved. Same problems a couple of months ago I felt unwell again and asked for a blood test. My TSH had gone up to 8.1. Having read the thread here I queried this with the GP who has emailed my concerns to the Pharmaceutical Society. My dose has been increased to 150mcgs, although I do not know the outcome of the GPs email.
TEVA Levo New formulation 
New lactose free formulation for Teva
Levothyroxine getting less effective?
Has anyone noticed a change in symptoms with new formula Levothyroxine UK?
